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MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. De plus, nous expédions MACC1 Kits (10) et MACC1 Protéines (4) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 40 products:
Human Polyclonal MACC1 Primary Antibody pour IF (p), IHC (p) - ABIN706526
Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. dans Molecular medicine reports 2015
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Human Polyclonal MACC1 Primary Antibody pour IHC, IHC (p) - ABIN4332277
Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. dans International journal of clinical and experimental medicine 2015
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Human Polyclonal MACC1 Primary Antibody pour ELISA, IHC - ABIN5582886
Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway. dans Journal of hematology & oncology 2016
Human Polyclonal MACC1 Primary Antibody pour IHC, IHC (p) - ABIN4332275
Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. dans Neuro-oncology 2013
Metastasis-associated in colon cancer 1 is expressed at early stages of colorectal oncogenesis within the affected colonic tissue in colorectal cancer patient cohort.
MACC1 is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer (CRC (Montrer CALR Anticorps)). Data suggest that some small molecules with antineoplastic activity inhibit MACC1 transcription in CRC (Montrer CALR Anticorps) and prevent liver metastasis in CRC (Montrer CALR Anticorps); lovastatin and rottlerin are the antineoplastic agents used here.
MACC1 regulates Fas (Montrer FAS Anticorps) mediated apoptosis through STAT1 (Montrer STAT1 Anticorps)/3 - Mcl-1 (Montrer MCL1 Anticorps) signaling in solid cancers.
High expression of MACC1 is associated with non-small cell lung cancer.
MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.
SPON2 (Montrer SPON2 Anticorps) is a transcriptional target of the metastasis gene MACC1. SPON2 (Montrer SPON2 Anticorps) induces cell motility in vitro and CRC (Montrer CALR Anticorps) metastasis in mice. In patients, SPON2 (Montrer SPON2 Anticorps) serves as prognostic indicator for CRC (Montrer CALR Anticorps) metastasis and survival, and might represent a promising target for therapeutic approaches.
High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.
Elevated Orai1 (Montrer ORAI1 Anticorps) and STIM1 (Montrer STIM1 Anticorps) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.
Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.
A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (Montrer FASN Anticorps) are positively correlated and responsible for the poor prognoses in gastric cancer patients.
Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.
HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer
MACC1 has a role in colorectal cancer and can be used for imaging in xenografts
MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009
SH3 domain-containing protein 7a5
, metastasis-associated in colon cancer protein 1
, putative binding protein 7a5