anti-Metastasis Associated in Colon Cancer 1 (MACC1) Anticorps

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. De plus, nous expédions MACC1 Kits (10) et MACC1 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  
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Top anti-MACC1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 40 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$307.45
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher 10 to 12 Days
$375.38
Détails
Humain Lapin Inconjugué IHC, IHC (p), SimWes Simple Western: MACC1 Antibody [NBP1-89352] - Simple Western lane view shows a specific band for MACC1 in 0.2 mg/ml of RT-4 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89352] - Staining of human endometrium shows strong cytoplasmic positivity in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$439.69
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Western Blot: MACC1 Antibody [NBP1-89351] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human cell line A-431 Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89351] - Staining of human duodenum shows cytoplasmic positivity in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$439.69
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 16 Days
$175.80
Détails
Humain Lapin Cy3 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$417.45
Détails
Humain Lapin Cy5 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$417.45
Détails
Humain Lapin Cy7 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$417.45
Détails
Humain Lapin Cy5.5 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$417.45
Détails

MACC1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine) , ,


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anti-MACC1 Anticorps mieux référencés

  1. Human Polyclonal MACC1 Primary Antibody pour IF (p), IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. dans Molecular medicine reports 2015 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MACC1 Primary Antibody pour IHC, IHC (p) - ABIN4332277 : Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. dans International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MACC1 Primary Antibody pour ELISA, IHC - ABIN5582886 : Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway. dans Journal of hematology & oncology 2016 (PubMed)

  4. Human Polyclonal MACC1 Primary Antibody pour IHC, IHC (p) - ABIN4332275 : Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. dans Neuro-oncology 2013 (PubMed)

Plus d’anticorps contre MACC1 partenaires d’interaction

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Metastasis-associated in colon cancer 1 is expressed at early stages of colorectal oncogenesis within the affected colonic tissue in colorectal cancer patient cohort.

  2. MACC1 is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer (CRC (Montrer CALR Anticorps)). Data suggest that some small molecules with antineoplastic activity inhibit MACC1 transcription in CRC (Montrer CALR Anticorps) and prevent liver metastasis in CRC (Montrer CALR Anticorps); lovastatin and rottlerin are the antineoplastic agents used here.

  3. MACC1 regulates Fas (Montrer FAS Anticorps) mediated apoptosis through STAT1 (Montrer STAT1 Anticorps)/3 - Mcl-1 (Montrer MCL1 Anticorps) signaling in solid cancers.

  4. High expression of MACC1 is associated with non-small cell lung cancer.

  5. MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.

  6. SPON2 (Montrer SPON2 Anticorps) is a transcriptional target of the metastasis gene MACC1. SPON2 (Montrer SPON2 Anticorps) induces cell motility in vitro and CRC (Montrer CALR Anticorps) metastasis in mice. In patients, SPON2 (Montrer SPON2 Anticorps) serves as prognostic indicator for CRC (Montrer CALR Anticorps) metastasis and survival, and might represent a promising target for therapeutic approaches.

  7. High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.

  8. Elevated Orai1 (Montrer ORAI1 Anticorps) and STIM1 (Montrer STIM1 Anticorps) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  9. Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  10. A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (Montrer FASN Anticorps) are positively correlated and responsible for the poor prognoses in gastric cancer patients.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 profil antigène

Profil protéine

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • metastasis associated in colon cancer 1 (MACC1) anticorps
  • metastasis associated in colon cancer 1 (Macc1) anticorps
  • 7a5 anticorps
  • 4732474O15Rik anticorps
  • Gm267 anticorps
  • RGD1309838 anticorps
  • SH3BP4L anticorps

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-MACC1 (MACC1) Anticorps
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