Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) Kits ELISA

MMADHC encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. De plus, nous expédions Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria Anticorps (52) et Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria Protéines (6) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
MMADHC 27249 Q9H3L0
MMADHC 109129  
MMADHC 362134  
Comment commander chez anticorps-enligne
  • +33 (0)1 76 63 32 65
  • +33 (0)1 74 18 08 22
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria Kits ELISA sur anticorps-enligne.fr

Showing 4 out of 4 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Rat
  96 Tests Connectez-vous pour afficher 13 to 17 Days
788,70 €
Détails
Humain
  96 Tests Connectez-vous pour afficher 13 to 17 Days
788,70 €
Détails
Souris
  96 Tests Connectez-vous pour afficher 13 to 17 Days
788,70 €
Détails
Poulet
  96 Tests Connectez-vous pour afficher 13 to 17 Days
1.013,20 €
Détails

Plus Kits ELISA pour Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria partenaires d'interaction

Human Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) interaction partners

  1. the MMACHC (Montrer MMACHC Kits ELISA)-MMADHC complex is a 1:1 heterodimer, where the interaction region overlaps with the MMACHC (Montrer MMACHC Kits ELISA)-Cbl (Montrer CBL Kits ELISA) binding site

  2. analysis of crystal structure of the globular C-terminal domain of human CblD, which is sufficient for its interaction with MMADHC or CblC (Montrer CBLC Kits ELISA), and for supporting the cytoplasmic cobalamin trafficking pathway

  3. specific regions of MMADHC are involved in differential regulation of adenosylcobalamin and methylcobalamin synthesis

  4. Subcellular location of MMACHC (Montrer MMACHC Kits ELISA) and MMADHC, two human proteins central to intracellular vitamin B(12) metabolism.

  5. The function of MMADHC is exerted through its structured C-terminal domain via interactions with MMACHC (Montrer MMACHC Kits ELISA).

  6. MMADHC mutations are associated with methylmalonic aciduria and homocystinuria.

  7. MMADHC was confirmed as a binding partner for MMACHC (Montrer MMACHC Kits ELISA) both in vitro (SPR (Montrer SPR Kits ELISA)) and in vivo (bacterial two-hybrid system).

  8. mutations in a gene designated MMADHC (currently named C2orf25) are responsible for the cblD defect in vitamin B12 (Montrer NDUFB3 Kits ELISA) metabolism; various mutations are associated with each of the three biochemical phenotypes of the disorder

Mouse (Murine) Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) interaction partners

  1. During organogenesis Mmachc (Montrer MMACHC Kits ELISA) and Mmadhc may interact in only a subset of cells.

Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) profil antigène

Antigen Summary

This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.

Gene names and symbols associated with MMADHC

  • methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria (MMADHC) anticorps
  • methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria (Mmadhc) anticorps
  • 2010311D03Rik anticorps
  • AI314967 anticorps
  • C2orf25 anticorps
  • cblD anticorps
  • CL25022 anticorps
  • RGD1303272 anticorps

Protein level used designations for MMADHC

methylmalonic aciduria and homocystinuria type D homolog, mitochondrial , methylmalonic aciduria and homocystinuria type D protein, mitochondrial , protein C2orf25, mitochondrial , likely ortholog of H. sapiens chromosome 2 open reading frame 25 (C2orf25)

GENE ID SPECIES
424311 Gallus gallus
27249 Homo sapiens
109129 Mus musculus
362134 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) Kits ELISA
Avez-vous cherché autre chose?