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anti-Myostatin (MSTN) Anticorps

The protein encoded by MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. De plus, nous expédions Myostatin Protéines (76) et Myostatin Kits (71) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MSTN 2660 O14793
MSTN 17700 O08689
MSTN 29152 O35312
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Top anti-Myostatin Anticorps sur anticorps-enligne.fr

Showing 10 out of 235 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Western blot analysis using Myostatin mouse mAb against truncated Myostatin-His recombinant protein (1) . 100 μL Connectez-vous pour afficher 6 to 8 Days
399,32 €
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-GDF8 N-term Pab (ABIN388821) in mouse liver tissue lysate. GDF8 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with GDF8 antibody (N-term )(ABIN388821), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Poulet Inconjugué EIA   50 μg Connectez-vous pour afficher 8 to 10 Days
319,00 €
Détails
Humain Souris Inconjugué WB 0.1 mL Connectez-vous pour afficher 8 to 10 Days
396,00 €
Détails
Humain Lapin Inconjugué EIA, IHC (p) 50 μg Connectez-vous pour afficher 8 to 10 Days
379,50 €
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 50 μL Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Bovine Inconjugué WB   0.1 mg Connectez-vous pour afficher 2 to 3 Days
289,14 €
Détails
Humain Souris Inconjugué IHC, WB Western Blot staining of a control protein  Lane 1: Recombinant protein 10 ng/Lane, Reducing  Lane 2: Recombinant protein 1 ng/Lane, Reducing  Recombinant protein Myostatin Propeptide Human (E.coli, Tag free) was subjected to SDS PAGE followed by Western Blot with ABIN2532791 (Myostatin Propeptide Human, , Mouse Monoclonal Antibody, Clone: 4B9) at a concentration of 1 μg/ml. Stained with DAB. Immunohistochemical staining of formalin-fixed paraffin-embedded human sceletal muscle using this product at a concentration of 2 µg/mL (original magnification, 20x (left) and 40x (right)). Detection DAB. Positive cytoplasmic staining in myocytes. 0.1 mg Connectez-vous pour afficher 2 to 3 Days
314,29 €
Détails
Humain Souris Inconjugué WB Western Blot staining of a control protein  Lane 1: Recombinant protein 10 ng/Lane, Reducing  Lane 2: Recombinant protein 1 ng/Lane, Reducing  Lane 3: Recombinant protein 1 ng/Lane, Non-reducing  Lane 4: Recombinant protein 10 ng/Lane, Non-reducing  Recombinant protein Myostatin Propeptide Human (E.coli, Tag free) was subjected to SDS PAGE followed by Western Blot with ABIN2532792 (Myostatin Propeptide Human, , Mouse Monoclonal Antibody, Clone: 6E8) at a concentration of 1 μg/ml. Stained with DAB. Immunohistochemical staining of formalin-fixed paraffin-embedded human sceletal muscle using this product at a concentration of 2 µg/mL (original magnification, 20x (left) and 40x (right)). Detection DAB.  Positive cytoplasmic staining in myocytes. 0.1 mg Connectez-vous pour afficher 2 to 3 Days
314,29 €
Détails

MSTN Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Myostatin Anticorps mieux référencés

  1. Human Polyclonal MSTN Primary Antibody pour EIA - ABIN115510 : Wolfman, McPherron, Pappano, Davies, Song, Tomkinson, Wright, Zhao, Sebald, Greenspan, Lee: Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. dans Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 4 references for ABIN115510

  2. Human Polyclonal MSTN Primary Antibody pour WB - ABIN108525 : McPherron AC,Lee SJ: Double muscling in cattle due to mutations in the myostatin gene. dans Proc Natl Acad Sci U S A 1997 (PubMed)
    Show all 3 references for ABIN108525

  3. Human Polyclonal MSTN Primary Antibody pour EIA, IHC (p) - ABIN357462 : Hamrick, McPherron, Lovejoy: Bone mineral content and density in the humerus of adult myostatin-deficient mice. dans Calcified tissue international 2002 (PubMed)
    Show all 3 references for ABIN357462

  4. Human Monoclonal MSTN Primary Antibody pour ELISA, WB - ABIN969306 : Awano, Takeshima, Okizuka, Saiki, Yagi, Matsuo: Wide ranges of serum myostatin concentrations in Duchenne muscular dystrophy patients. dans Clinica chimica acta; international journal of clinical chemistry 2008 (PubMed)
    Show all 2 references for ABIN969306

  5. Human Monoclonal MSTN Primary Antibody pour WB - ABIN1108369 : Wójcik, Nogalska, Engel, Askanas: Myostatin and its precursor protein are increased in the skeletal muscle of patients with Type-II muscle fibre atrophy. dans Folia morphologica 2008 (PubMed)

Plus d’anticorps contre Myostatin partenaires d’interaction

Zebrafish Myostatin (MSTN) interaction partners

  1. improving muscle growth in a fish species by mixing a classical strategy, such as compensatory growth, and a biotechnological approach, such as the use of recombinant proteins for inhibiting the biological actions of MSTN(Myostatin)

  2. the expression of myostatin during development and the effects of its knock-down on various genes such as muscle regulatory transcription factors (MRFs), muscle-specific (Montrer EIF3K Anticorps) proteins (MSP (Montrer MST1 Anticorps)), and insulin (Montrer INS Anticorps)-like growth factors (IGFs).

  3. Epistatic analyses suggest a possible genetic interaction between Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) and Myostatin in regulation of slow and fast twitch muscle myofibrillogenesis

Medaka Myostatin (MSTN) interaction partners

  1. TALENs-mediated gene disruption of myostatin produces a larger phenotype of medaka with an apparently compromised immune system

  2. Findings suggest that myostatin (MSTN) function is required for regulating the appropriate growth of skeletal muscle in medaka

Human Myostatin (MSTN) interaction partners

  1. Myostatin mRNA expression in skeletal muscle was significantly reduced compared with pre-exercise values at all time points with no difference between exercise intensity.

  2. Low expression of serum MSTN is associated with Cachexia Prevention in Patients with Medullary Thyroid Cancer.

  3. Myostatin was differentially expressed in the muscle and adipose tissue in relation to physical activity and dysglycaemia

  4. Our results suggest that serum levels of myostatin and irisin (Montrer FNDC5 Anticorps) are related in patients with type 2 diabetes

  5. Matrix metalloproteinase 14 (Montrer MMP14 Anticorps) was highly expressed in uterine leiomyoma and correlated with myostatin and activin A (Montrer INHBA Anticorps) mRNA expression. Moreover, MMP14 (Montrer MMP14 Anticorps) and myostatin mRNA expression correlated significantly and directly with the intensity of dysmenorrhea.

  6. A synthetic peptide corresponding to this decorin (Montrer DCN Anticorps) region dose-dependently inhibited the response to myostatin in cardiomyocytes

  7. Findings suggest that GDF8 and CTGF (Montrer CTGF Anticorps) may play critical roles in the regulation of proliferative events in human granulosa cells.

  8. Myostatin concentrations in plasma and protein expression in placental tissue are significantly higher in women with preeclampsia. Cytokine production by first-trimester placental tissues was altered following myostatin treatment.

  9. Myostatin is a well-described negative regulator of postnatal skeletal and cardiac muscle mass and modulates metabolic processes. It functions in the heart, skeletal muscle, and brain. Review.

  10. Plasma myostatin levels are increased in chronic obstructive pulmonary disease patients who have cor pulmonale.

Mouse (Murine) Myostatin (MSTN) interaction partners

  1. A role for Nfix (Montrer MLZE Anticorps) in postnatal skeletal muscle development and regeneration and Myostatin gene expression regulation.

  2. Myostatin deletion specifically affects skeletal muscle mitochondrial function and redox status. Decreased mitochondrial function and oxidative markers persisted in aged mstn KO mice. However, muscle hypertrophy and the redox status related to this genotype appeared as beneficial side effects attenuating the age effect, as metabolic changes become less pronounced in comparison with WT mice.

  3. A synthetic peptide corresponding to this decorin (Montrer DCN Anticorps) region dose-dependently inhibited the response to myostatin in cardiomyocytes

  4. myostatin may play an important role in maintaining ankle and wrist joint health.

  5. Agouti-related peptide (AgRP (Montrer AGRP Anticorps)) neuron activation acutely reprograms gene expression in BAT (Montrer BAAT Anticorps) toward a myogenic signature, including increased expression of myostatin. Interference with myostatin activity improves insulin (Montrer INS Anticorps) sensitivity that was impaired by AgRP (Montrer AGRP Anticorps) neurons activation.

  6. Increased expression of myostatin in heart muscle cells caused interstitial fibrosis via activation of the TAK-1 (Montrer NR2C2 Anticorps)-MKK3 (Montrer MAP2K3 Anticorps)/6-p38 (Montrer CRK Anticorps) signaling pathway

  7. study is the first to report an in vivo association between vitamin D, myostatin, and the regulation of muscle mass

  8. Report myostatin expression in early postnatal mouse masseter and rectus femoris muscles.

  9. An age-dependent decline in serum Gdf8 levels was identified.

  10. Mstn may negatively regulate Igf2 expression to control postnatal skeletal muscle growth, however differences in growth between male and female mice are not readily explained by changes in expression of Igf family members.

Pig (Porcine) Myostatin (MSTN) interaction partners

  1. These results indicate that myostatin mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 (Montrer FOXO3 Anticorps) and glucocorticoid receptor (Montrer NR3C1 Anticorps) binding to its promoter.

  2. Loss of MSTN increases muscle mass in pigs, which may help increase pork production for consumption in the future.

  3. Data show that the protein level of The protein level of myostatin (MSTN) was decreased in the mutant cloned pigs compared with the wild-type controls.

  4. Single nucleotide polymorphisms in the MYOD1 (Montrer MYOD1 Anticorps) and GDF8 genes are associated with genetic transcription during myogenesis in pigs.

  5. The level of myostatin inversely correlated with miR (Montrer MYLIP Anticorps)-27a in fat and heart of pigs and also in proliferating porcine myoblasts. Overexpression of miR (Montrer MYLIP Anticorps)-27a in porcine myoblasts promoted cell proliferation by reducing the expression of myostatin.

  6. MSTN g.435G>A and g.447A>G affected carcass traits in pigs

  7. The genotypes of MSTN g.435G > A and g.447A > G SNPs in Duroc pigs were studied. The 435GG/447AA (Montrer COL16A1 Anticorps) individually had significantly higher average daily gain, body weight at 70 d and 150 d , and a lower age at 110 kg than 435AA/447GG individuals.

  8. Porcine MSTN could be upregulated by isobutyl-1-methylxanthine , MyoD (Montrer MYOD1 Anticorps), and PPARgamma (Montrer PPARG Anticorps) but downregulated by C/EBPalpha (Montrer CEBPA Anticorps) and C/EBPbeta (Montrer CEBPB Anticorps).

  9. a vital enhancer region was identified between nucleotides -218 and -137 in promoter region of porcine myostatin

  10. It was concluded that myostatin is a factor broadly expressed in the internal organs and muscle tissues of pigs.

Cow (Bovine) Myostatin (MSTN) interaction partners

  1. Data indicate that the the promoter trap vector PIII-myostatin could knock out the bovine myostatin gene.

  2. The effects of myostatin and myogenic factor 5 (Montrer MYF5 Anticorps) polymorphisms on growth and muscle traits of Marchigiana breed were assessed.

  3. we demonstrate zygote injection of TALEN mRNA can also produce gene-edited cattle and sheep. In both species we have targeted the myostatin (MSTN) gene.

  4. proof-of-concept study is the first to produce MSTN mutations in cattle, and may allow the development of genetically modified strains of double-muscled cattle.

  5. Mutations in the leader peptide of the bovine myostatin gene effectively promote the proliferation of bovine fibroblast cells.

  6. there were 18 SNPs identified in the Qinchuan cattle promoter region compared with those of other cattle compared to the Red Angus cattle myostatin promoter region.

  7. A 3-way interaction of myostatin genotype (MG), season, and trigonometric function periodicities of 24 h and 12 h indicate that a genotype x environment interaction exists for MG.

  8. These results show for the first time that myostatin regulates the differential expression of chemokines in skeletal muscle cells.

  9. bovine myostatin is a specific target of miR (Montrer MYLIP Anticorps)-27b and that miRNAs contribute to explain additive phenotypic hypertrophy in Piedmontese cattle selected for the MSTN gene mutation

  10. Mutations in the myostatin gene, responsible for the double muscling condition in cattle, were targeted to estimate the time since the most recent common ancestor. Each myostatin allele had a recent common ancestor (<400 years ago).

Goat Myostatin (MSTN) interaction partners

  1. The reduced expression of myostatin gene was achieved and measured in clonal fibroblast cells by real-time PCR.

  2. This study also suggests the importance of siRNA-mediated knockdown of MSTN as a potential alternative to increase muscle mass and meat production.

  3. A study of the MSTN 5' upstream region and investigation of 5'UTR (Montrer UTS2R Anticorps) TTTTA deletion was carried out in seven different Indian goat breeds. An 1181 bp fragment of 5' upstream region of MSTN gene was PCR amplified, cloned, and sequenced.

  4. myostatin plays a negative role in regulating the expression of adipogenesis related genes in goat fetal fibroblasts.

  5. Polymorphisms of myostatin gene as markers associated with growth in Boer goats.

Horse (Equine) Myostatin (MSTN) interaction partners

  1. The effect of an Equine Repetitive Element 1 insertion in the promoter of the myostatin gene, which is involved in muscle development, was also investigated.

  2. Myostatin mRNA but not protein was increased in skeletal muscle of obese compared with lean animals. Myostatin mRNA was increased in crest fat of obese animals and protein was undetectable. Serum myostatin was higher in obese than lean animals.

  3. The tissue-specific presence of myostatin, the moystatin receptor (activin receptor IIB (Montrer ACVR2B Anticorps), ActRIIB (Montrer ACVR2B Anticorps)), follistatin (Montrer FST Anticorps) and perilipin (Montrer PLIN1 Anticorps), genes and proteins across a range of equine tissues, were examined.

  4. The candidate for racing performance genomic region contained eight genes annotated by ENSEMBL, including the myostatin gene (MSTN).

  5. Polymorphisms of the MSTN promoter region in 5 horse breeds in Poland are reported.

  6. significant association observed between genotype and mRNA abundance for untrained horses with the C/C cohort having highest MSTN mRNA levels,T/T group lowest levels and C/T group intermediate levels; following training there was significant decrease in MSTN mRNA which was most apparent for the C/C cohort

  7. Exon 2 of the MSTN gene, which encodes part of the TGF-beta (Montrer TGFB1 Anticorps) pro-peptide, was sequenced in 332 horses of 20 different breeds and compared with the horse MSTN gene sequence deposited in GenBank. The sequences obtained revealed the presence of 11 haplotypes represented by 10 variable nucleotide mutations, eight of them corresponding to amino acid sequence changes.

  8. Variation at the MSTN gene influences speed in Thoroughbred horses.

  9. This study demonstrates that the g.66493737C>T single nucleotide polymorphism in MSTN provides the most powerful genetic marker for prediction of race distance aptitude in Thoroughbreds.

  10. Characterized the horse (Equus caballus) MSTN gene and identified and analysed single nucleotide polymorphisms (SNPs) in breeds of different morphological types.

Rabbit Myostatin (MSTN) interaction partners

  1. Alignment of sequence data with the GenBank sequence of the rabbit MSTN gene identified three single nucleotide polymorphisms (SNPs). Significant linkage was found between the novel SNP c.373+234G>A and nine carcass composition traits.

  2. These results suggest that the mutations in the upstream regulatory region of the MSTN gene are beneficial to the rabbit soma development, and the mutations can be used as molecular markers for the selection of the meat quality of rabbits.

  3. Studied and compared mRNA levels of myostatin (MSTN), myogenin (MyoG (Montrer MYOG Anticorps)), and myosin heavy chain (MyHC (Montrer MYH13 Anticorps)) in skeletal muscles of two rabbit breeds with different body sizes and growth rates.

  4. indicated that MSTN is not an important source of variability for performance traits, at least in the rabbit population

Myostatin (MSTN) profil antigène

Profil protéine

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Gene names and symbols associated with anti-Myostatin (MSTN) Anticorps

  • myostatin (MSTN) anticorps
  • myostatin b (mstnb) anticorps
  • myostatin (AaeL_AAEL003224) anticorps
  • myostatin (BRAFLDRAFT_290840) anticorps
  • myostatin (Mstn) anticorps
  • myostatin (mstn) anticorps
  • myostatin (LOC100125998) anticorps
  • Cmpt anticorps
  • GDF-8 anticorps
  • Gdf8 anticorps
  • MSLHP anticorps
  • mstn anticorps
  • NV13143 anticorps
  • zgc:109749 anticorps

Protein level used designations for anti-Myostatin (MSTN) Anticorps

Growth/differentiation factor 8 , growth/differentiation factor-8 , GDF-8 , growth differentiation factor 8 , growth/differentiation factor 8 , mstn-1 , myostatin-1 , myostatin-B , zfMSTN-1 , myostatin , compact

GENE ID SPECIES
100303659 Meleagris gallopavo
798441 Danio rerio
5577632 Aedes aegypti
7221321 Branchiostoma floridae
100118233 Nasonia vitripennis
100379652 Ictalurus punctatus
100529165 Oryzias latipes
2660 Homo sapiens
17700 Mus musculus
29152 Rattus norvegicus
373964 Gallus gallus
399534 Sus scrofa
281187 Bos taurus
403433 Canis lupus familiaris
100860887 Capra hircus
100033832 Equus caballus
443449 Ovis aries
100735599 Cavia porcellus
100125998 Oryctolagus cuniculus
710114 Macaca mulatta
100968757 Pan paniscus
470605 Pan troglodytes
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