Naked Cuticle Homolog 2 (Drosophila) (NKD2) Kits ELISA

NKD2 encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. De plus, nous expédions Naked Cuticle Homolog 2 (Drosophila) Anticorps (52) et Naked Cuticle Homolog 2 (Drosophila) Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Souris NKD2 NKD2 72293 Q8VE28
Anti-Humain NKD2 NKD2 85409 Q969F2
Anti-Rat NKD2 NKD2 308068  
Comment commander chez anticorps-enligne
  • +33 (0)1 76 63 32 65
  • +33 (0)1 74 18 08 22
  • Commandez enligne
  • orders@anticorps-enligne.fr

Plus Kits ELISA pour Naked Cuticle Homolog 2 (Drosophila) partenaires d'interaction

Zebrafish Naked Cuticle Homolog 2 (Drosophila) (NKD2) interaction partners

  1. data indicate that zebrafish Nkd1 (Montrer NKD1 Kits ELISA) and Nkd2 function to limit both canonical and non-canonical Wnt (Montrer WNT2 Kits ELISA) signaling

Mouse (Murine) Naked Cuticle Homolog 2 (Drosophila) (NKD2) interaction partners

  1. studies provide compelling evidence that downregulation of NKD2 expression and alterations in associated regulated pathways have a significant role in driving OS tumor growth and metastasis

  2. Mouse naked cuticle 2 (mNkd2) is a direct transcriptional target of Hoxc8 (Montrer HOXC8 Kits ELISA) in vivo.

Human Naked Cuticle Homolog 2 (Drosophila) (NKD2) interaction partners

  1. NKD2 is the key molecular marker to study the progression of osteosarcoma development, and it may be used for better prognosis of the disease in early stage

  2. curcumin significantly inhibited the proliferation of colorectal cancer cells and upregulated the expression of NKD2 in SW620 colorectal cancer cells.

  3. NKD2 regulates osteosarcoma cell proliferation and apoptosis by inhibiting the Wnt (Montrer WNT2 Kits ELISA) signaling.MiR-130b targets NKD2 and regulates the Wnt (Montrer WNT2 Kits ELISA) signaling to promote proliferation and inhibit apoptosis of osteosarcoma cells.

  4. NKD2 is frequently methylated in human breast cancer, and the expression of NKD2 is regulated by promoter region methylation.

  5. NKD2 methylation is associated with cell differentiation, TNM (Montrer ODZ1 Kits ELISA) stage and distant metastasis significantly (all P < 0.05), and the overall survival time is longer in NKD2 unmethylated group compared to NKD2 methylated group (P < 0.05).

  6. NKD2 antagonizes Wnt signaling: myristoylated NKD2 interacts with Dvl-1 at the plasma membrane, and this interaction leads to their mutual ubiquitin-mediated proteasomal degradation.

  7. NKD2 represents a candidate target of 5p amplifications in soft tissue sarcomas and might play a crucial role during the progression of this disease.

  8. Naked2 acts as a cargo recognition and targeting (CaRT) protein to ensure proper delivery, tethering, and fusion of TGF-alpha (Montrer TGFA Kits ELISA)-containing vesicles to a distinct region at the basolateral surface of polarized epithelial cells.

  9. identify an EGFR (Montrer EGFR Kits ELISA)-independent action of TGF-alpha (Montrer TGFA Kits ELISA), in which it protects Naked2 from proteasomal degradation, thus ensuring its delivery to the basolateral surface of polarized epithelial cells

Naked Cuticle Homolog 2 (Drosophila) (NKD2) profil antigène

Antigen Summary

This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NKD2

  • naked cuticle homolog 2b (nkd2b) anticorps
  • naked cuticle 2 homolog (Drosophila) (Nkd2) anticorps
  • naked cuticle homolog 2 (Drosophila) (NKD2) anticorps
  • naked cuticle homolog 2 (Drosophila) (Nkd2) anticorps
  • naked cuticle homolog 2a (nkd2a) anticorps
  • 2210403L10Rik anticorps
  • AW212591 anticorps
  • Naked2 anticorps
  • nkd2 anticorps
  • nkd2l anticorps

Protein level used designations for NKD2

naked cuticle homolog 2 , protein naked cuticle homolog 2-like , mNkd2 , naked cuticle 1 homolog , naked-2 , protein naked cuticle homolog 2 , Dvl-binding protein NKD2 , naked cuticle 2 homolog , naked 2a

GENE ID SPECIES
794221 Danio rerio
72293 Mus musculus
85409 Homo sapiens
308068 Rattus norvegicus
100049175 Danio rerio
Avez-vous cherché autre chose?