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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. De plus, nous expédions Olfactory Receptor, Family 51, Subfamily E, Member 2 Anticorps (35) et Olfactory Receptor, Family 51, Subfamily E, Member 2 Protéines (4) et beaucoup plus de produits pour cette protéine.
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Transgenic mice overexpressing PSGR in the prostate were reported to develop an acute inflammatory response followed by emergence of low grade prostatic intraepithelial neoplasia, whereas mice with compound PSGR overexpression and loss of PTEN exhibited accelerated formation of invasive prostate adenocarcinoma. (Review)
Olfr78 is involved in the regulation of hormone secretion from such cells, as evoked by nutritional compounds
in addition to its role in olfaction, Olfr78 acts as a hypoxia sensor in the breathing circuit by sensing lactate produced when oxygen levels decline
SCFAs produced by the gut (Montrer GUSB Kits ELISA) microbiota modulate blood pressure via Olfr78 and Gpr41 (Montrer FFAR3 Kits ELISA).
Two genes, OR51E2 and SIM2 (Montrer SIM2 Kits ELISA), and two miRNAs, miR (Montrer MLXIP Kits ELISA)-200c and miR (Montrer MLXIP Kits ELISA)-200b, showed significant association with prostate cancer.
Plasma membrane preparations showed that OR51E2 protein is present at the melanocyte cell surface.
PSGR overexpression synergizes with loss of PTEN to accelerate prostate cancer development, and present a novel bigenic mouse model that mimics the human condition
Pyk2-NDRG1 axis is possibly involved in conveying the anti-proliferative effect of beta-ionone in prostate cancer cells.
Increased expression of prostate-specific G-protein-coupled receptor is associated with prostate intraepithelial neoplasia and prostate cancers
two functional promoters regulate the transcriptional expression of PSGR in human prostate tissues, and PSGR is a new target for IL-6 (Montrer IL6 Kits ELISA) transcriptional regulation
PSGR overexpression is associated with higher percentage of pathologic stage, pT3, and a higher level of preoperative serum PSA in Prostate Cancer
expression of PSGR and PSGR2 (Montrer OR51E1 Kits ELISA) relative to AMACR (Montrer AMACR Kits ELISA) in prostate cancer; AMACR (Montrer AMACR Kits ELISA) was the most overexpressed, but in some cases expression of AMACR (Montrer AMACR Kits ELISA) was not significantly elevated while PSGR and/or PSGR2 (Montrer OR51E1 Kits ELISA) were substantially elevated
We identified androstenone derivatives as ligands for the recombinant receptor PSGR
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
G-protein coupled receptor RA1c
, olfactory receptor 51E2
, olfactory receptor 78
, olfactory receptor MOR18-2
, olfactory receptor OR11-16
, olfactory receptor, family 51, subfamily E, member 3 pseudogene
, olfactory receptor, family 52, subfamily A, member 2
, prostate specific G-protein coupled receptor
, prostate-specific G-protein coupled receptor