anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Anticorps

The protein encoded by PAK7 is a member of the PAK family of Ser/Thr protein kinases. De plus, nous expédions PAK7 Protéines (13) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PAK7 57144 Q9P286
PAK7 241656 Q8C015
PAK7 311450 D4A280
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Top anti-PAK7 Anticorps sur anticorps-enligne.fr

Showing 10 out of 99 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB Anti- PAK5 Picoband antibody, IHC(P) IHC(P): Human Glioma Tissue 100 μg Connectez-vous pour afficher 8 to 11 Days
340,48 €
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-PAK5 Pab (ABIN392438) in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK5 (arrow) was detected using purified polyclonal antibody. Data is kindly provided by Drs. Z.M. Jaffer and J. Chernoff from the Fox Chase Cancer Center (Philadelphia, PA). Formalin-fixed and paraffin-embedded human brain tissue reacted with PAK5 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué EIA, IP, WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Chien Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 6 to 8 Days
337,56 €
Détails
Humain Lapin Inconjugué IHC (p), WB Mouse Pak7 Antibody (N-term) (ABIN657995) western blot analysis in mouse stomach tissue lysates (35 µg/lane). This demonstrates the Pak7 antibody detected the Pak7 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western Blot (WB) analysis of specific cells using PAK5 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué EIA, IF, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Lapin Inconjugué IF, IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti PAK7/PAK5/MBT Polyclonal Antibody, Unconjugated (ABIN671496) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti PAK7/PAK5/MBT Polyclonal Antibody, Unconjugated (ABIN671496) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 9 to 12 Days
304,36 €
Détails

PAK7 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine) ,


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Rat (Rattus) ,


anti-PAK7 Anticorps mieux référencés

  1. Human Polyclonal PAK7 Primary Antibody pour ICC, ELISA - ABIN1002958 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. dans The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre PAK7 partenaires d’interaction

Human P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. Data suggest expression of ECAD (E-cadherin (Montrer CDH1 Anticorps)) in bladder cancer cell lines correlates with presence of intercellular junctions and level of PAK5 (Montrer PAK6 Anticorps) (p21 (Montrer CDKN1A Anticorps)-activated kinase PAK5 (Montrer PAK6 Anticorps) protein) expression; endogenous PAK5 (Montrer PAK6 Anticorps) is localized to intercellular junctions and interacts with ECAD (Montrer CDH1 Anticorps); depletion of PAK5 (Montrer PAK6 Anticorps) expression reduces integrity of intercellular junctions; PAK5 (Montrer PAK6 Anticorps) mRNA levels are reduced in bladder cancer compared with normal controls.

  2. model suggests PAK5 self-association interferes with AID binding to the catalytic domain, thus maintaining its high activity.

  3. PAK7 expression is significantly downregulated in human masticatory mucosa during wound healing

  4. PAK7 is overexpressed in human esophageal squamous cell cancer samples and correlated with lymph node metastasis.

  5. E47 (Montrer TCF3 Anticorps) is a novel substrate of PAK5 (Montrer PAK6 Anticorps), and PAK5 (Montrer PAK6 Anticorps)-mediated phosphorylation of E47 (Montrer TCF3 Anticorps) promotes epithelial-mesenchymal transition and metastasis of colon cancer.

  6. Aurora-A induced PAK7 expression in esophageal cancer cells.

  7. results suggest that the inhibition of PAK5 by RNA interference might efficiently suppress tumor development of glioma cells with PAK5 high expression.

  8. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma.

  9. PAK7 promotes cell proliferation and tumorigenesis

  10. It inhibits glioma cell migration and invasion potentially through the PAK5 (Montrer PAK6 Anticorps)-Egr1 (Montrer EGR1 Anticorps)-MMP2 (Montrer MMP2 Anticorps) signaling pathway.

Xenopus laevis P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. Xenopus PAK5 regulates convergent extension movements in vivo by modulating the calcium-mediated cell-cell adhesion in blastomeres.

Mouse (Murine) P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. PAK-7 p21-activated kinase 5 knockout mice are more sensitive to the stimulant effects of amphetamine

  2. functional deficits in PAK5, PAK6 (Montrer PAK6 Anticorps) and PAK5/PAK6 (Montrer PAK6 Anticorps) knockout mice

  3. PAK 5 is involved in formalin-induced inflammatory nociception through regulation of MAPK-induced c-Fos-activation and formalin-specific transient receptor potential-channels.

  4. These results implicate Pak5 in Pacsin1 (Montrer PACSIN1 Anticorps)- and Synaptojanin1-mediated synaptic vesicle trafficking.

  5. PAK5 may provide a molecular rationale for late-stage complications in diabetes.

  6. Our results indicate that Pak5 and Pak6 (Montrer PAK6 Anticorps) together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

PAK7 profil antigène

Profil protéine

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with PAK7

  • p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7) anticorps
  • p21 protein (Cdc42/Rac)-activated kinase 7 (pak7) anticorps
  • p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) anticorps
  • p21-activated kinase 7 (LOC100340742) anticorps
  • 2900083L08Rik anticorps
  • 6430627N20 anticorps
  • PAK-5 anticorps
  • PAK-7 anticorps
  • Pak5 anticorps

Protein level used designations for PAK7

PAK-5 , PAK-7 , p21(CDKN1A)-activated kinase 7 , p21-activated kinase 5 , p21-activated kinase 7 , p21CDKN1A-activated kinase 7 , protein kinase PAK5 , serine/threonine-protein kinase PAK 7 , serine/threonine-protein kinase PAK7 , p21 (CDKN1A)-activated kinase 7

GENE ID SPECIES
57144 Homo sapiens
398224 Xenopus laevis
241656 Mus musculus
100340742 Oryctolagus cuniculus
311450 Rattus norvegicus
469876 Pan troglodytes
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