PITPNM Family Member 3 (PITPNM3) Kits ELISA

PITPNM3 encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. De plus, nous expédions PITPNM Family Member 3 Anticorps (34) et PITPNM Family Member 3 Protéines (3) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain PITPNM3 PITPNM3 83394 Q9BZ71
Anti-Souris PITPNM3 PITPNM3 327958 Q3UHE1
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Plus Kits ELISA pour PITPNM Family Member 3 partenaires d'interaction

Human PITPNM Family Member 3 (PITPNM3) interaction partners

  1. CCL18 can increase the invasive ability of non-small cell lung cancer cells by binding to its receptor Nir1.

  2. CCL18 (Montrer CCL18 Kits ELISA) enhances hepatocellular carcinoma (HCC (Montrer FAM126A Kits ELISA)) cell migration, invasion, and epithelial-mesenchymal transition (EMT (Montrer ITK Kits ELISA)) through the expression of PITPNM3 and the activation of the NF-kappaB (Montrer NFKB1 Kits ELISA) signaling pathway.

  3. Data indicate that PYK2 N-terminal domain interacting receptor 1 (Nir1) could induce epithelial-mesenchymal transition by stabilising Snail (Montrer SNAI1 Kits ELISA) via the PI3K (Montrer PIK3CA Kits ELISA)/Akt (Montrer AKT1 Kits ELISA)/GSK3beta (Montrer GSK3b Kits ELISA)/Snail (Montrer SNAI1 Kits ELISA) signalling pathway through binding to CCL18 (Montrer CCL18 Kits ELISA).

  4. Our observations of the PITPNM3 p.Q626H mutation carriers confirm that CORD5 (Montrer GUCY2D Kits ELISA) is a disease not to mix with other retinal degenerations mapped to 17p13.

  5. CCL18 (Montrer CCL18 Kits ELISA) derived from Tumor-associated macrophages (TAMs) lays a critical role in promoting breast cancer metastasis via its receptor, PITPNM3.

  6. Thus, mutations in PITPNM3 do not appear to be a major cause of cone or cone-rod dystrophy.

  7. Our finding on the first mutation in the human homologue of Drosophila rdgB (Montrer PITPNM1 Kits ELISA) indicates novel pathways and a potential important role of the PITPNM3 in mammalian phototransduction.

  8. Mutation in the PYK2 (Montrer PTK2B Kits ELISA)-binding domain of PITPNM3 causes autosomal dominant cone dystrophy (CORD5 (Montrer GUCY2D Kits ELISA)) in two Swedish families.

PITPNM Family Member 3 (PITPNM3) profil antigène

Antigen Summary

This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PITPNM3

  • PITPNM family member 3 (PITPNM3) anticorps
  • PITPNM family member 3 (Pitpnm3) anticorps
  • A330068P14Rik anticorps
  • Ackr6 anticorps
  • AI848332 anticorps
  • CORD5 anticorps
  • Gm880 anticorps
  • NIR1 anticorps
  • RDGBA3 anticorps

Protein level used designations for PITPNM3

NIR-1 , PITPnm 3 , PYK2 N-terminal domain-interacting receptor 1 , atypical chemokine receptor 6 , cone rod dystrophy 5 , membrane-associated phosphatidylinositol transfer protein 3 , phosphatidylinositol transfer protein, membrane-associated 3 , retinal degeneration B alpha 3 , pyk2 N-terminal domain-interacting receptor 1

GENE ID SPECIES
83394 Homo sapiens
327958 Mus musculus
489445 Canis lupus familiaris
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