POC1 Centriolar Protein Homolog B (Chlamydomonas) Protéines (POC1B)

Required for ciliogenesis (By similarity).. De plus, nous expédions POC1B Anticorps (34) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
POC1B 282809 Q8TC44
POC1B 382406 Q8BHD1
POC1B    
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Top POC1B Protéines sur anticorps-enligne.fr

Showing 5 out of 5 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$7,759.50
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$7,759.50
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$405.71
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 10 to 12 Days
$785.40
Détails
Levure Poisson Zèbre His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,386.17
Détails

POC1B Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Zebrafish (Danio rerio)

Plus protéines pour POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) partenaires d'interaction

Human POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) interaction partners

  1. Depletion of CEP295 blocks the incorporation of POC5 (Montrer POC5 Protéines) and POC1B into the distal portion of centrioles and suppresses the post-translational modification of centriolar microtubules . Our study thus uncovers a new role for CEP295 during centriole elongation.

  2. Intronic SNP in POC1B/GALNT4 (Montrer GALNT4 Protéines) locus (rs11105306) was associated with NT-proBNP levels in patients with acute coronary syndrome (ACS (Montrer PLA2G15 Protéines)). The POC1B/GALNT4 (Montrer GALNT4 Protéines) SNP was not associated with higher risk of cardiovascular death.

  3. Study found that homozygous POC1B mutation, i.e., c.737C --> T(p.T246 M), cosegregated with the phenotype of a tested family, indicating that POC1B gene was the most possible pathogenic gene for paroxysmal kinesigenic dyskinesia

  4. Study indicates that POC1B is required for retinal integrity, and is proposed POC1B mutations as a probable cause for Joubert syndrome with severe polycystic kidney disease.

  5. POC1B is a novel gene for a new disease typical of cone-rod dystrophy except that patients did not report night blindness.

  6. POC1B mutations result in a defect of the photoreceptor sensory cilium and thus affect cone and rod photoreceptors.

  7. Poc1A (Montrer POC1A Protéines) and Poc1B play redundant, but essential, roles in generation of stable centrioles, but Poc1B may have additional independent functions during cell cycle progression.

  8. Poc1B is required for primary ciliogenesis; Poc1 provides a molecular link between the assembly and stability of centrioles for ciliary-based motility in T. thermophila and cilia formation and function in zebrafish and humans

  9. Based on these data, we propose that Pix1 and Pix2 (Montrer POC1A Protéines) are microtubule-associated adaptor proteins that likely contribute to a range of developmental and cell division processes.

Zebrafish POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) interaction partners

  1. data suggest that poc1b is required for normal development and ciliogenesis of retinal photoreceptor sensory cilia and other cilia

  2. Poc1B knockdown causes ciliary defects & morphological phenotype consistent with ciliopathies; Poc1 provides link between assembly & stability of centrioles for ciliary-based motility in Tetrahymena & cilia formation & function in D rerio & humans

Profil protéine POC1B

Profil protéine

Required for ciliogenesis (By similarity).

Gene names and symbols associated with POC1B

  • POC1 centriolar protein B (POC1B)
  • POC1 centriolar protein B (Poc1b)
  • POC1 centriolar protein B (poc1b)
  • 4933430F16Rik Protéine
  • fl36w17 Protéine
  • PIX1 Protéine
  • TUWD12 Protéine
  • wdr51b Protéine
  • wu:fl36w17 Protéine
  • zgc:63538 Protéine

Protein level used designations for POC1B

POC1 centriolar protein homolog B , WD repeat-containing protein 51B , WD repeat domain 51B

GENE ID SPECIES
282809 Homo sapiens
382406 Mus musculus
386932 Danio rerio
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