anti-Phosphomannomutase 2 (PMM2) Anticorps

The protein encoded by PMM2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. De plus, nous expédions PMM2 Protéines (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PMM2 5373 O15305
PMM2 54128 Q9Z2M7
PMM2 302915  
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Top anti-PMM2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 62 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PMM2 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: MCF7 Whole Cell <br /> PMM2 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB PMM2 Antibody (C-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PMM2 antibody detected the PMM2 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Cobaye Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Souris Inconjugué WB Western Blot analysis of PMM2 expression in transfected 293T cell line by PMM2 monoclonal antibody (M01), clone 2E9. Lane 1: PMM2 transfected lysate(28.1 KDa). Lane 2: Non-transfected lysate. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Souris Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Souris Inconjugué WB PMM2 monoclonal antibody (M02), clone 2A5. Western Blot analysis of PMM2 expression in K-562. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cells, using PMM2 antibody. Immunohistochemistry of paraffin-embedded human prostate using PMM2 antibody at dilution of 1:100 (x40 lens). 100 μL Connectez-vous pour afficher 16 Days
$476.15
Détails

PMM2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human ,
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Mouse (Murine)


Rat (Rattus)


anti-PMM2 Anticorps mieux référencés

  1. Human Polyclonal PMM2 Primary Antibody pour ELISA, WB - ABIN562290 : Yuste-Checa, Brasil, Gámez, Underhaug, Desviat, Ugarte, Pérez-Cerdá, Martinez, Pérez: Pharmacological Chaperoning: A Potential Treatment for PMM2-CDG. dans Human mutation 2016 (PubMed)

Plus d’anticorps contre PMM2 partenaires d’interaction

Zebrafish Phosphomannomutase 2 (PMM2) interaction partners

  1. Morphant embryos had developmental abnormalities consistent with Congenital disorder of glycosylation resulting from mutations in pmm2, including craniofacial defects and impaired motility associated with altered motor neurogenesis.

Xenopus laevis Phosphomannomutase 2 (PMM2) interaction partners

  1. The data show for the first time that a knockdown of phosphomannomutase 2 influences in vivo the non-canonical Wnt (Montrer WNT2 Anticorps) signalling during early embryogenesis.

Human Phosphomannomutase 2 (PMM2) interaction partners

  1. Four patients were diagnosed with PMM2-CDG at the age of 8 years or later as their neurological symptoms were quite mild and they had been able to participate in regular school programs. We report patients with p.Val231Met/p.Arg239Trp and p.Ile120Thr/p.Gly228Cys genotypes which may cause milder variants of PMM2-CDG

  2. This functional mouse model of PMM2-CDG, in vitro assays and identification of the novel gp130 biomarker all shed light on the human disease, and moreover, provide the essential tools to test potential therapeutics for this untreatable disease.

  3. We propose that the PMM2 promoter mutation alters tissue-specific chromatin loop formation, with consequent organ-specific deficiency of PMM2 leading to the restricted phenotype of HIPKD. Our findings extend the spectrum of genetic causes for both HI and PKD (Montrer PRKD1 Anticorps) and provide insights into gene regulation and PMM2 pleiotropy

  4. work describes the functional analysis of 9 PMM2 mutant proteins frequently found in congenital disorder of glycosylation type Ia(PMM2-CDG)patients; results suggest that some loss-of-function mutations detected in PMM2-CDG patients could be destabilizing

  5. A mild neurological phenotype of PMM2-CDG marked by preserved ambulatory ability and autonomy and associated with L32R mutation is particularly frequent in Italy.

  6. Data indicate genome-wide significant association at multiple single nucleotide polymorphism (SNPs) near ATP binding cassette transporter 1 (ABCA1 (Montrer ABCA1 Anticorps)) at 9q31.1 and suggestive evidence of association in phosphomannomutase 2 (PMM2) at 16p13.2.

  7. We conclude that electroretinogram signs of on-pathway dysfunction can be detected in the early stages of PMM2-Congenital disorder of glycosylation.

  8. Hypertrophic cardiomyopathy with cardiac rupture and tamponade caused by congenital disorder of glycosylation type Ia with PMM2 mutations in two siblings.

  9. The presence of this deletion-insertion mutation at cDNA position 565 suggests that this site in the PMM2 gene may be a hotspot for chromosomal breakage.

  10. A Japanese patient with congenital disorder of glycosylation type Ia had a novel nonsense mutation (R194X) in the PMM2 gene.

Mouse (Murine) Phosphomannomutase 2 (PMM2) interaction partners

  1. This functional mouse model of PMM2-CDG, in vitro assays and identification of the novel gp130 biomarker all shed light on the human disease, and moreover, provide the essential tools to test potential therapeutics for this untreatable disease.

  2. Pmm2 activity in jejunum increased during the early stages of life, and it decreased at 1 month old, as does the amount of mannose incorporated into glycoproteins, whereas in the ileum, they were not affected by age.

  3. Pmm2 immunoreactivity seen in prenatal brain until postnatal and adult stage and restricted in neuronal cell bodies.

  4. These results indicate that Pmm2 is essential for early development of mice.

PMM2 profil antigène

Profil protéine

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Gene names and symbols associated with PMM2

  • phosphomannomutase 2 (pmm2) anticorps
  • phosphomannomutase 2 (PMM2) anticorps
  • phosphomannomutase 2 S homeolog (pmm2.S) anticorps
  • phosphomannomutase 2 (PTRG_02815) anticorps
  • phosphomannomutase 2 (Tsp_00480) anticorps
  • phosphomannomutase 2 (Pmm2) anticorps
  • AI585868 anticorps
  • C86848 anticorps
  • cb626 anticorps
  • CDG1 anticorps
  • CDG1a anticorps
  • CDGS anticorps
  • MGC82869 anticorps
  • PMI anticorps
  • PMI1 anticorps
  • PMM 2 anticorps
  • pmm2 anticorps
  • zgc:56149 anticorps

Protein level used designations for PMM2

phosphomannomutase 2 , phosphomannose isomerase 1 , PMM 2

GENE ID SPECIES
368229 Danio rerio
427679 Gallus gallus
444370 Xenopus laevis
6341038 Pyrenophora tritici-repentis Pt-1C-BFP
10901767 Trichinella spiralis
100196649 Salmo salar
100216238 Xenopus (Silurana) tropicalis
100528607 Ictalurus punctatus
5373 Homo sapiens
54128 Mus musculus
302915 Rattus norvegicus
510978 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-PMM2 (PMM2) Anticorps
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