anti-Poly(rC) Binding Protein 2 (PCBP2) Anticorps

The protein encoded by PCBP2 appears to be multifunctional. De plus, nous expédions PCBP2 Protéines (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PCBP2 5094 Q15366
PCBP2 18521 Q61990
PCBP2 363005  
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Top anti-PCBP2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 62 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-PCBP2 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-PCBP2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Souris Inconjugué WB PCBP2 monoclonal antibody (M02), clone 1B6. Western Blot analysis of PCBP2 expression in K-562. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of hnRNP E2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry: PCBP2 Antibody [NBP1-83241] - Immunofluorescence: [NBP1-83241] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: PCBP2 Antibody [NBP1-83241] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$439.69
Détails
Humain Lapin Inconjugué ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2, antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 10% SDS PAGE antibody diluted at 1:500 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Humain Souris Inconjugué IF, IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to PCBP2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$430.00
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell (antibody concentration 10 µg/mL). Western blot analysis of PCBP2 over-expressed 293 cell line, cotransfected with PCBP2 Validated Chimera RNAi used as specificity and loading control. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails

PCBP2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human ,
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Mouse (Murine)


Rat (Rattus)


anti-PCBP2 Anticorps mieux référencés

  1. Human Monoclonal PCBP2 Primary Antibody pour IF, IHC (p) - ABIN562121 : Fujimura, Kano, Murata: Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies. dans RNA (New York, N.Y.) 2008 (PubMed)
    Show all 9 Pubmed References

  2. Cow (Bovine) Polyclonal PCBP2 Primary Antibody pour IHC, WB - ABIN2778923 : Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. dans Mammalian genome : official journal of the International Mammalian Genome Society 2005 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal PCBP2 Primary Antibody pour ICC, IF - ABIN4344023 : Flynn, Martin, Spitale, Do, Sagan, Zarnegar, Qu, Khavari, Quake, Sarnow, Chang: Dissecting noncoding and pathogen RNA-protein interactomes. dans RNA (New York, N.Y.) 2014 (PubMed)

  4. Human Monoclonal PCBP2 Primary Antibody pour WB - ABIN394008 : Kim, Chang, Yun, Yang, Hong, Kim, Um, Lee, Lee, Hwang: Chloride intracellular channel 1 identified using proteomic analysis plays an important role in the radiosensitivity of HEp-2 cells via reactive oxygen species production. dans Proteomics 2010 (PubMed)

Plus d’anticorps contre PCBP2 partenaires d’interaction

Human Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. Data suggest that the interaction between PCBP2 and the 3'UTR (Montrer UTS2R Anticorps) of the ARHGDIA (Montrer ARHGDIA Anticorps) mRNA may induce a local change in RNA structure that favors subsequent binding of miR (Montrer MLXIP Anticorps)-151-5p and miR-16 (Montrer GDE1 Anticorps), thus leading to the suppression of ARHGDIA (Montrer ARHGDIA Anticorps) expression.

  2. To promote intracellular iron flux, an iron chaperone appears to be essential for receiving iron from heme catabolism. Data suggest that PCBP2 competes with CPR (Montrer POR Anticorps) for binding HO1 (Montrer HMOX1 Anticorps); PCBP2 K homology 3 domain is important for HO1 (Montrer HMOX1 Anticorps)/PCBP2 interaction; heme prompts HO1 (Montrer HMOX1 Anticorps)/CPR (Montrer POR Anticorps) multimer and decreases HO1 (Montrer HMOX1 Anticorps)/PCBP2 multimer. [PCBP2 = poly(rC) binding protein 2; CPR (Montrer POR Anticorps) = cytochrome P450 reductase (Montrer POR Anticorps); HO1 (Montrer HMOX1 Anticorps) = heme oxidase 1]

  3. BC200 RNA interacts with hnRNP E1 (Montrer PCBP1 Anticorps) and E2 mainly through its unique 3' C-rich domain.

  4. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  5. These results suggest that FPN1 (Montrer SLC40A1 Anticorps) exports iron received from the iron chaperone PCBP2. Therefore, it was found that PCBP2 modulates cellular iron export, which is an important physiological process.

  6. PCBP2 was overexpressed in esophageal squamous cell carcinoma tissues and cell lines. PCBP2 expression promoted proliferation of ESCC cells. We also found that reduced PCBP2 expression might induce ESCC cell apoptosis with increased cleaved caspase3 expression. Overall, our findings indicated that PCBP2 might be involved in the ESCC progression and be considered as a new treatment target in ESCC.

  7. High expression of PCBP2 may contribute to sorafenib resistance in hepatocellular carcinoma cells.

  8. our data indicate that miR (Montrer MLXIP Anticorps)-214 may function as tumor suppressor in glioma by targeting PCBP2

  9. beta2-adrenergic receptor (Montrer ADRB2 Anticorps) signaling promotes pancreatic ductal adenocarcinoma progression by facilitating PCBP2-dependent c-myc (Montrer MYC Anticorps) expression.

  10. PCBP2 knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 overexpression obtained oppose effects.

Mouse (Murine) Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  2. data suggest that PCBP2 regulates p73 (Montrer ARHGAP24 Anticorps) expression via mRNA stability and p73 (Montrer ARHGAP24 Anticorps)-dependent biological function in ROS (Montrer ROS1 Anticorps) production and cellular senescence.

  3. PCBP2 overexpression rescues the Meis1 (Montrer MEIS1 Anticorps) effects of Akt (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps) pathway and hypertrophy of cardiomyocytes.

  4. These data reveal that Pcbp1 (Montrer PCBP1 Anticorps) and Pcbp2 are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.

  5. PCBP2 knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 overexpression obtained oppose effects.

  6. Our analysis of PCBP1 (Montrer PCBP1 Anticorps) and PCBP2 expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.

  7. This study demonstrates for the first time that alpha-CP2 functions as a transcriptional activator by binding to a single-stranded poly(C) sequence.

  8. This study provides evidence that PCBP2 and hnRNP A1 (Montrer HNRNPA1 Anticorps) bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.

  9. PCBP2-AIP4 (Montrer ITCH Anticorps) axis defines a new signaling cascade for MAVS (Montrer MAVS Anticorps) degradation and 'fine tuning' of antiviral innate immunity.

Pig (Porcine) Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. These results indicated that Nsp1beta of porcine reproductive and respiratory syndrome virus is able to bind and interact with cellular PCBP2 strongly in both the infected cells and plasmid transfected cells.

  2. Overall, the results presented here point toward an important role for PCBP1 (Montrer PCBP1 Anticorps) and PCBP2 in regulating porcine reproductive and respiratory syndrome virus RNA synthesis via binding to viral nonstructural protein 1beta.

PCBP2 profil antigène

Profil protéine

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PCBP2

  • poly(rC) binding protein 3 (pcbp3) anticorps
  • poly(rC) binding protein 2 (pcbp2) anticorps
  • poly(rC) binding protein 2 (PCBP2) anticorps
  • poly(rC) binding protein 2 (Pcbp2) anticorps
  • poly(rC) binding protein 2 L homeolog (pcbp2.L) anticorps
  • alphaCP-2 anticorps
  • AW412548 anticorps
  • fb36h02 anticorps
  • hnRNP-E2 anticorps
  • HNRNPE2 anticorps
  • HNRPE2 anticorps
  • Hnrpx anticorps
  • PCBP2 anticorps
  • PCBP3 anticorps
  • wu:fb36h02 anticorps
  • zgc:55964 anticorps

Protein level used designations for PCBP2

poly(rC) binding protein 2 , poly(rC) binding protein 3 , poly(rC)-binding protein 2 , PolyrC-binding protein 2 , poly(rc)-binding protein 2 , alpha-CP2 , heterogeneous nuclear ribonucleoprotein E2 , heterogenous nuclear ribonucleoprotein E2 , hnRNP E2 , CBP , CTBP , heterogeneous nuclear ribonucleoprotein X , hnRNP X , putative heterogeneous nuclear ribonucleoprotein X , heterogeneous nuclear ribonucleoprotein

GENE ID SPECIES
448044 Xenopus (Silurana) tropicalis
733863 Xenopus (Silurana) tropicalis
100194880 Salmo salar
100528911 Ictalurus punctatus
5094 Homo sapiens
477596 Canis lupus familiaris
540653 Bos taurus
18521 Mus musculus
363005 Rattus norvegicus
321844 Danio rerio
399399 Xenopus laevis
397665 Sus scrofa
420965 Gallus gallus
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