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anti-Poly(rC) Binding Protein 2 (PCBP2) Anticorps

The protein encoded by PCBP2 appears to be multifunctional.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain PCBP2 PCBP2 5094 Q15366
Anti-Souris PCBP2 PCBP2 18521 Q61990
Anti-Rat PCBP2 PCBP2 363005  
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Top anti-PCBP2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 57 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PCBP2 Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-PCBP2 Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Humain Souris Inconjugué WB PCBP2 monoclonal antibody (M02), clone 1B6. Western Blot analysis of PCBP2 expression in K-562. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry: PCBP2 Antibody [NBP1-83241] - Immunofluorescence: [NBP1-83241] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: PCBP2 Antibody [NBP1-83241] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Humain Lapin Inconjugué ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2, antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 10% SDS PAGE antibody diluted at 1:500 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Humain Souris Inconjugué IF, IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to PCBP2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Connectez-vous pour afficher 7 to 8 Days
369,60 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell (antibody concentration 10 µg/mL). Western blot analysis of PCBP2 over-expressed 293 cell line, cotransfected with PCBP2 Validated Chimera RNAi used as specificity and loading control. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Souris Inconjugué EIA, IF, IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
583,00 €
Détails

Plus d’anticorps contre PCBP2 partenaires d’interaction

Human Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. BC200 RNA interacts with hnRNP E1 (Montrer PCBP1 Anticorps) and E2 mainly through its unique 3' C-rich domain.

  2. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  3. These results suggest that FPN1 (Montrer SLC40A1 Anticorps) exports iron received from the iron chaperone PCBP2. Therefore, it was found that PCBP2 modulates cellular iron export, which is an important physiological process.

  4. PCBP2 was overexpressed in esophageal squamous cell carcinoma tissues and cell lines. PCBP2 expression promoted proliferation of ESCC cells. We also found that reduced PCBP2 expression might induce ESCC cell apoptosis with increased cleaved caspase3 expression. Overall, our findings indicated that PCBP2 might be involved in the ESCC progression and be considered as a new treatment target in ESCC.

  5. High expression of PCBP2 may contribute to sorafenib resistance in hepatocellular carcinoma cells.

  6. our data indicate that miR (Montrer MLXIP Anticorps)-214 may function as tumor suppressor in glioma by targeting PCBP2

  7. beta2-adrenergic receptor (Montrer ADRB2 Anticorps) signaling promotes pancreatic ductal adenocarcinoma progression by facilitating PCBP2-dependent c-myc (Montrer MYC Anticorps) expression.

  8. PCBP2 knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 overexpression obtained oppose effects.

  9. Protein and mRNA levels of PCBP2 were down-regulated under insulin (Montrer INS Anticorps)-resistant conditions. Over-expression of PCBP2 inhibits HIF1alpha (Montrer HIF1A Anticorps) and STAT3 (Montrer STAT3 Anticorps) pathway.

  10. STAT3 (Montrer STAT3 Anticorps) functions via cellular PCBP2 to regulate B-cell lytic susceptibility by restraining Epstein-Barr Virus lytic activation.

Mouse (Murine) Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  2. data suggest that PCBP2 regulates p73 (Montrer ARHGAP24 Anticorps) expression via mRNA stability and p73 (Montrer ARHGAP24 Anticorps)-dependent biological function in ROS (Montrer ROS1 Anticorps) production and cellular senescence.

  3. PCBP2 overexpression rescues the Meis1 (Montrer MEIS1 Anticorps) effects of Akt (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps) pathway and hypertrophy of cardiomyocytes.

  4. These data reveal that Pcbp1 (Montrer PCBP1 Anticorps) and Pcbp2 are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.

  5. PCBP2 knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 overexpression obtained oppose effects.

  6. Our analysis of PCBP1 (Montrer PCBP1 Anticorps) and PCBP2 expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.

  7. This study demonstrates for the first time that alpha-CP2 functions as a transcriptional activator by binding to a single-stranded poly(C) sequence.

  8. This study provides evidence that PCBP2 and hnRNP A1 (Montrer HNRNPA1 Anticorps) bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.

  9. PCBP2-AIP4 (Montrer ITCH Anticorps) axis defines a new signaling cascade for MAVS (Montrer MAVS Anticorps) degradation and 'fine tuning' of antiviral innate immunity.

Pig (Porcine) Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. These results indicated that Nsp1beta of porcine reproductive and respiratory syndrome virus is able to bind and interact with cellular PCBP2 strongly in both the infected cells and plasmid transfected cells.

  2. Overall, the results presented here point toward an important role for PCBP1 (Montrer PCBP1 Anticorps) and PCBP2 in regulating porcine reproductive and respiratory syndrome virus RNA synthesis via binding to viral nonstructural protein 1beta.

PCBP2 profil antigène

Profil protéine

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PCBP2

  • poly(rC) binding protein 3 (pcbp3) anticorps
  • poly(rC) binding protein 2 (pcbp2) anticorps
  • poly(rC) binding protein 2 (PCBP2) anticorps
  • poly(rC) binding protein 2 (Pcbp2) anticorps
  • poly(rC) binding protein 3 (PCBP3) anticorps
  • alphaCP-2 anticorps
  • AW412548 anticorps
  • fb36h02 anticorps
  • hnRNP-E2 anticorps
  • HNRNPE2 anticorps
  • HNRPE2 anticorps
  • Hnrpx anticorps
  • PCBP2 anticorps
  • PCBP3 anticorps
  • wu:fb36h02 anticorps
  • zgc:55964 anticorps

Protein level used designations for PCBP2

poly(rC) binding protein 2 , poly(rC) binding protein 3 , poly(rC)-binding protein 2 , PolyrC-binding protein 2 , poly(rc)-binding protein 2 , alpha-CP2 , heterogeneous nuclear ribonucleoprotein E2 , heterogenous nuclear ribonucleoprotein E2 , hnRNP E2 , CBP , CTBP , heterogeneous nuclear ribonucleoprotein X , hnRNP X , putative heterogeneous nuclear ribonucleoprotein X , heterogeneous nuclear ribonucleoprotein

GENE ID SPECIES
448044 Xenopus (Silurana) tropicalis
733863 Xenopus (Silurana) tropicalis
100194880 Salmo salar
100528911 Ictalurus punctatus
5094 Homo sapiens
477596 Canis lupus familiaris
540653 Bos taurus
18521 Mus musculus
363005 Rattus norvegicus
321844 Danio rerio
399399 Xenopus laevis
397665 Sus scrofa
420965 Gallus gallus
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