Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Kits ELISA

POLR3B encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. De plus, nous expédions Polymerase (RNA) III (DNA Directed) Polypeptide B Anticorps (42) et Polymerase (RNA) III (DNA Directed) Polypeptide B Protéines (3) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Rat POLR3B POLR3B 362858  
Anti-Humain POLR3B POLR3B 55703 Q9NW08
Anti-Souris POLR3B POLR3B 70428 P59470
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Plus Kits ELISA pour Polymerase (RNA) III (DNA Directed) Polypeptide B partenaires d'interaction

Human Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) interaction partners

  1. Multicenter retrospective study to collect neuroradiologic, clinical, and molecular data of patients with mutations in POLR3A (Montrer POLR3A Kits ELISA) and POLR3B without the classic MRI (Montrer C7ORF49 Kits ELISA) phenotype: diffuse hypomyelination is not an obligatory feature of POLR3-related disorders; two distinct patterns, selective involvement of the corticospinal tracts and cerebellar atrophy, are added to the MRI (Montrer C7ORF49 Kits ELISA) presentation of POLR3-related disorders

  2. first reports of long deletions causing POLR3-related leukodystrophy, suggesting that deletions and duplications in POLR3A (Montrer POLR3A Kits ELISA) or POLR3B should be investigated in patients with a compatible phenotype

  3. Mutations in POLR3A (Montrer POLR3A Kits ELISA) or POLR3B are rare in patients with unclassified hypomyelination.

  4. INMAP as a model regulator of CENP-B (Montrer CENPB Kits ELISA)

  5. These results suggest that INMAP might function through p53 (Montrer TP53 Kits ELISA)/p21 (Montrer CDKN1A Kits ELISA) pathways.

  6. Most patients with 4H leukodystrophy carried the common c.1568T>A POLR3B mutation on one allele.

  7. MRI (Montrer C7ORF49 Kits ELISA) in patients with POLR3B mutations revealed smaller cerebellar structures, especially vermis, than those in POLR3A (Montrer POLR3A Kits ELISA) mutations. MRI (Montrer C7ORF49 Kits ELISA) also showed milder hypomyelination in patients with POLR3B mutations than those with POLR3A (Montrer POLR3A Kits ELISA) mutations

  8. Investigated POLR3A (Montrer POLR3A Kits ELISA) and POLR3B mutations in patients with genetically unexplained hypomyelinating leukodystrophies with features of Pol III-related leukodystrophies. Recessive mutations in POLR3A (Montrer POLR3A Kits ELISA) or POLR3B were uncovered in all 14 patients.

  9. study reports INMAP is a truncated version of POLR3B, and is up-regulated in several human cancer cell lines; results suggest that INMAP may function through the p53 (Montrer TP53 Kits ELISA) and AP-1 (Montrer FOSB Kits ELISA) pathways, providing a possible link of its activity with tumourigenesis

  10. Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy

Mouse (Murine) Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) interaction partners

  1. The Polr3b in the hippocampus in the prefrontal cortex of the DBA (Montrer RPS19 Kits ELISA)/2 J strain were up-regulated.

Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) profil antigène

Antigen Summary

This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with POLR3B

  • polymerase (RNA) III (DNA directed) polypeptide B (Polr3b) anticorps
  • polymerase (RNA) III (DNA directed) polypeptide B (POLR3B) anticorps
  • 2700078H01Rik anticorps
  • A330032P03Rik anticorps
  • C128 anticorps
  • C85372 anticorps
  • HLD8 anticorps
  • RGD1565311 anticorps
  • RPC2 anticorps

Protein level used designations for POLR3B

DNA-directed RNA polymerase III subunit RPC2 , DNA-directed RNA polymerase III 127.6 kDa polypeptide , DNA-directed RNA polymerase III subunit B , RNA polymerase III subunit C2 , C128 , DNA-directed RNA polymerase III B , RNA polymerase III subunit RPC2 homolog

GENE ID SPECIES
362858 Rattus norvegicus
418071 Gallus gallus
474531 Canis lupus familiaris
55703 Homo sapiens
70428 Mus musculus
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