anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) Anticorps

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. De plus, nous expédions Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Protéines (4) et Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
KCNA5 3741 P22460
KCNA5 16493 Q61762
KCNA5 25470 P19024
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Top anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 90 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 8 to 11 Days
340,48 €
Détails
Humain Lapin Inconjugué WB WB Suggested Anti-KCNA5 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué IP, WB 0.1 mL Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Humain Lapin Inconjugué WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Humain Lapin Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Chien Lapin Inconjugué IF (p), IHC (p), WB   100 μL Connectez-vous pour afficher 9 to 12 Days
304,36 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué WB KCNA5 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the KCNA5 antibody detected the KCNA5 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué IHC (fro), IF, IP, WB   0.1 mg Connectez-vous pour afficher 8 to 10 Days
418,00 €
Détails

KCNA5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Anticorps mieux référencés

  1. Human Polyclonal KCNA5 Primary Antibody pour WB - ABIN265025 : Mori, Matsubara, Folco, Siegel, Koren: The transcription of a mammalian voltage-gated potassium channel is regulated by cAMP in a cell-specific manner. dans The Journal of biological chemistry 1994 (PubMed)
    Show all 4 references for 265025

  2. Human Polyclonal KCNA5 Primary Antibody pour WB - ABIN610625 : OSullivan, Kennedy, Casey, Day, Corrigan, Wodak: Anabolic-androgenic steroids: medical assessment of present, past and potential users. dans The Medical journal of Australia 2000 (PubMed)
    Show all 4 references for 610625

  3. Dog (Canine) Polyclonal KCNA5 Primary Antibody pour IF (p), IHC (p) - ABIN735158 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. dans Basic research in cardiology 2014 (PubMed)

  4. Cow (Bovine) Polyclonal KCNA5 Primary Antibody pour IP, WB - ABIN449232 : Zhou, Ma, Huang: Specific antibodies to the external vestibule of voltage-gated potassium channels block current. dans The Journal of general physiology 1998 (PubMed)

  5. Human Polyclonal KCNA5 Primary Antibody pour ELISA, WB - ABIN1451442 : Curran, Landes, Keating: Molecular cloning, characterization, and genomic localization of a human potassium channel gene. dans Genomics 1992 (PubMed)

Plus d’anticorps contre Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 partenaires d’interaction

Human Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) interaction partners

  1. our finding indicated that KCNA5 protein may interact with Cav-1 (Montrer CAV1 Anticorps), thereby contributing to the proliferation and early transformation of mammary cells.

  2. Studies demonstrate that DNA hypermethylation contributes to epigenetic repression of the KCNA5 locus and that the resulting suppression of the Kv1.5 ion channel supports cancer cell proliferation.

  3. Kv1.5 expression is increased in osteosarcoma cells and tissues and shRNA mediated silencing of Kv1.5 results in cell proliferation inhibition, cell cycle arrest, and induces cell apoptosis.

  4. demonstrate that PK treatment cleaved mature membrane-bound (75kDa (Montrer INPP5B Anticorps)) Kv1.5 channels at a single locus in the S1-S2 linker, producing 42-kDa N-terminal fragments and 33-kDa C-terminal fragments

  5. These results indicate that CHIP decreases the Kv1.5 protein level and functional channel by facilitating its degradation in concert with chaperone Hsc70 (Montrer HSPA8 Anticorps)

  6. The expression of Kv1.5 channel protein changes with atrial fibrillation but not with age, rheumatic heart diseases, and sex in atrial fibrillation.

  7. One KCNA5 variant, H463R, was a novel mutation; the histidine at codon 463 is located in the S5-pore loop, in the vicinity of the pore of KV1.5 subunit. The other variant, T527M, showed a gain-of-function effect with an enhanced steady-state activation.

  8. The KCNA5 promoter is marked in cancer cells with PcG-dependent chromatin repressive modifications that increase in hypoxia.

  9. Mutations in KCNA5 gene is not associated with pulmonary arterial hypertension.

  10. Protein kinase C (Montrer PKC Anticorps) inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels

Mouse (Murine) Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) interaction partners

  1. Silencing of Kv1.5 improved endothelium-dependent vasodilatation in thoracic aorta from type 2 diabetes mice.

  2. Intracellular urate taken up by UATs enhanced Kv1.5 protein expression and function in HL-1 (Montrer ASGR1 Anticorps) atrial myocytes.

  3. JAK3 (Montrer JAK3 Anticorps) contributes to the regulation of membrane Kv1.5 protein abundance and activity, an effect sensitive to ouabain and thus possibly involving Na(+)/K(+) ATPase (Montrer ATP1A1 Anticorps) activity.

  4. KV1.5, a DPO-1-sensitive KDR (Montrer KDR Anticorps) channel, plays a major role in determining microvascular tone and the response to vasoconstrictors and vasodilators.

  5. Kv1.5 channels in vascular smooth muscle play a critical role in coupling myocardial blood flow to cardiac metabolism.

  6. the Kv1.5 subunit has a role in electrical remodeling of preoptic GABAergic neurons

  7. MYO5A (Montrer MYO5A Anticorps) and MYO5B control functionally distinct steps in the surface trafficking of Kv1.5.

  8. e-LXA4 promoted a modest upregulation of Kv1.5 mRNA that was suppressed by LPS (Montrer TLR4 Anticorps) or IL-4 (Montrer IL4 Anticorps)/IL-13 (Montrer IL13 Anticorps).

  9. The combined down-regulation of Kv4.2 (Montrer KCND2 Anticorps), Kv1.5 and KChIP2 (Montrer KCNIP2 Anticorps) prior to the onset of HF may play an important role in the premature sudden death in this DCM model.

  10. cortactin (Montrer CTTN Anticorps) was required for N-cadherin (Montrer CDH2 Anticorps)-mediated enhancement of Kv1.5 channel activity

Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) profil antigène

Profil protéine

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).

Gene names and symbols associated with KCNA5

  • potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5) anticorps
  • potassium voltage-gated channel, shaker-related subfamily, member 5 (kcna5) anticorps
  • potassium voltage-gated channel, shaker-related subfamily, member 5 (Kcna5) anticorps
  • ATFB7 anticorps
  • HCK1 anticorps
  • HK2 anticorps
  • HPCN1 anticorps
  • kcna5 anticorps
  • Kv1 anticorps
  • Kv1.5 anticorps
  • PCN1 anticorps

Protein level used designations for KCNA5

potassium voltage-gated channel, shaker-related subfamily, member 5 , potassium voltage-gated channel subfamily A member 5-like , cardiac potassium channel , insulinoma and islet potassium channel , potassium channel 1 , potassium voltage-gated channel subfamily A member 5 , voltage-gated potassium channel HK2 , voltage-gated potassium channel protein Kv1.5 , voltage-gated potassium channel subunit Kv1.5 , KV1-5 , Potassium (K+) channel protein alpha 5 , RCK7 , RK4 , potassium voltage gated channel, shaker related subfamily, member 5 , shaker subfamily potassium channel Kv1.5 alpha subunit , delayed rectifier K+ channel , Kv1.5 potassium channel , potassium voltage-gated channel shaker-related subfamily member 5 , potassium voltage-gated channel shaker-related subfamily 5 , potassium channel Kv1.5 , voltage-gated potassium channel Kv1.5

GENE ID SPECIES
466930 Pan troglodytes
496997 Xenopus (Silurana) tropicalis
100431806 Pongo abelii
3741 Homo sapiens
16493 Mus musculus
25470 Rattus norvegicus
395115 Gallus gallus
403995 Canis lupus familiaris
474166 Sus scrofa
508960 Bos taurus
100008684 Oryctolagus cuniculus
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