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Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) Kits ELISA

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. De plus, nous expédions PCSK9 Anticorps (152) et PCSK9 Protéines (61) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PCSK9 255738 Q8NBP7
PCSK9 100102 Q80W65
PCSK9 298296 P59996
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Top PCSK9 Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 72 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.11 ng/mL 0.45-30 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 13 to 17 Days
772,39 €
Détails
Souris 10pg/mL 62.5-4000 pg/mL Mouse PCSK9 PicoKine ELISA Kit standard curve 96 Tests Connectez-vous pour afficher 8 to 11 Days
507,05 €
Détails
Singe 1.1 pg/mL 1.1-800 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 13 to 17 Days
874,71 €
Détails
Rat 1.19 ng/mL 3.12-200 ng/mL 96 Tests Connectez-vous pour afficher 11 to 15 Days
643,39 €
Détails
Porc 0.469 ng/mL 0.781-50 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Lapin 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Poulet 4.688 ng/mL 7.813-500 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Cobaye 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Souris 94-6000 pg/mL   1 kit Connectez-vous pour afficher 7 to 8 Days
768,00 €
Détails
Chien
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails

PCSK9 Kits ELISA mieux référencés

  1. Mouse (Murine) PCSK9 Kit ELISA pour Sandwich ELISA - ABIN2685159 : Seidah, Benjannet, Wickham, Marcinkiewicz, Jasmin, Stifani, Basak, Prat, Chretien: The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation. dans Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 references for ABIN2685159

  2. Human PCSK9 Kit ELISA pour Sandwich ELISA - ABIN820112 : Dogan, Akman, Simsek, Ozdem, Comak, Gokceoglu, Kardelen, Koyun: Assessment of left ventricular function by tissue Doppler echocardiography in pediatric chronic kidney disease. dans Renal failure 2015 (PubMed)
    Show all 2 references for ABIN820112

Plus Kits ELISA pour PCSK9 partenaires d'interaction

Human Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. the zymogen form of PCSK9 adopts a structure that is distinct from the processed form and is unable to bind a mimetic peptide based on the EGF (Montrer EGF Kits ELISA)-A domain of the LDLr (Montrer LDLR Kits ELISA).

  2. CRP (Montrer CRP Kits ELISA) increased PCSK9 expression by activating p38MAPK (Montrer MAPK14 Kits ELISA)-HNF1alpha (Montrer HNF1A Kits ELISA) pathway, with a certain downstream impairment in LDL metabolism in HepG2 cells.

  3. PCSK9 C-terminal domain (CTD) was found to be essential to induce LDLR (Montrer LDLR Kits ELISA) degradation both upon its overexpression in cells or via the extracellular pathway.

  4. Results show that circulating PCSK9 concentration increases with the severity of hepatic fat accumulation in patients at risk of nonalcoholic fatty liver disease.

  5. PCSK9 inhibition with alirocumab on top of statin treatment has the potential to lower LDL cholesterol in some autosomal recessive hypercholesterolemia patients.

  6. CRISPR-Cas9 therapy targeting the human PCSK9 gene in chimeric liver-humanized mice bearing human hepatocytes.

  7. PCSK9 regulates monocyte CCR2 expression and chemotaxis.

  8. PCSK9 is down-regulated in patients with rheumatoid arthritis.

  9. Carriers of the PCSK9 R46L genetic variant have lower very low-density lipoprotein and low-density lipoprotein particle concentrations, lower lipoprotein(a) levels, and lower secretory phospholipase A2 (Montrer YWHAZ Kits ELISA) and lipoprotein-associated phospholipase A2 activity, reducing cardiovascular risk.

  10. PCSK9 R46L carriers have lower levels of lipoprotein(a) and LDL cholesterol and is associated with reduced risk of aortic valve stenosis and myocardial infarction.

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. AdipoR activation by agonists regulated PCSK9 expression and inhibits atherosclerosis in apoE (Montrer APOE Kits ELISA)(-/-) mice.

  2. Adeno (Montrer ADORA2A Kits ELISA)-associated virus mediated infection with a mouse PCSK9 gain-of-function mutation is a rapid, easy, and efficient approach for inducing hypercholesterolemia and promoting abdominal aortic aneurysms in C57BL/6 mice infused with angiotensin II.

  3. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (Montrer CA2 Kits ELISA)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (Montrer LDLR Kits ELISA) degradation and promoting LDLR (Montrer LDLR Kits ELISA)-dependent hepatic cholesterol uptake.

  4. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor (Montrer LDLR Kits ELISA) Degradation.

  5. PCSK9 increases hepatic lipid and lipoprotein production via apoE (Montrer APOE Kits ELISA)- and LDLR (Montrer LDLR Kits ELISA)-dependent mechanisms

  6. Podocyte damage triggers marked inductions in plasma PCSK9, and knockout of Pcsk9 ameliorates dyslipidemia in a mouse model of nephrotic syndrome.

  7. polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating PCSK9.

  8. binding of PCSK9 to GRP94 (Montrer HSP90B1 Kits ELISA) protects LDLR (Montrer LDLR Kits ELISA) from degradation likely by preventing early binding of PCSK9 to LDLR (Montrer LDLR Kits ELISA)

  9. The absence of PCSK9 results in a sex- and tissue-specific subcellular distribution of the LDLR (Montrer LDLR Kits ELISA) and VLDLR (Montrer VLDLR Kits ELISA), which is determined by estradiol levels.

  10. that ox-LDL receptor-1 (Montrer OLR1 Kits ELISA) and PCSK9 positively influence each other's expression, especially during an inflammatory reaction

PCSK9 profil antigène

Antigen Summary

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Gene names and symbols associated with PCSK9

  • proprotein convertase subtilisin/kexin type 9 (pcsk9) anticorps
  • proprotein convertase subtilisin/kexin type 9 (PCSK9) anticorps
  • proprotein convertase subtilisin/kexin type 9 (Pcsk9) anticorps
  • proprotein convertase subtilisin/kexin type 9-like (LOC100620501) anticorps
  • AI415265 anticorps
  • AI747682 anticorps
  • FH3 anticorps
  • HCHOLA3 anticorps
  • LDLCQ1 anticorps
  • NARC-1 anticorps
  • Narc1 anticorps
  • PC9 anticorps

Protein level used designations for PCSK9

proprotein convertase subtilisin/kexin type 9 , convertase subtilisin/kexin type 9 preproprotein , neural apoptosis regulated convertase 1 , subtilisin/kexin-like protease PC9 , NARC-1 , convertase subtilisin , neural apoptosis-regulated convertase 1 , proprotein convertase 9 , proprotein convertase PC9 , proprotein convertase subtilisin/kexin type 9 preproprotein , Proprotein convertase 9 , Subtilisin/kexin-like protease PC9

GENE ID SPECIES
495509 Xenopus laevis
100150316 Danio rerio
100544916 Meleagris gallopavo
255738 Homo sapiens
100102 Mus musculus
298296 Rattus norvegicus
424664 Gallus gallus
100731533 Cavia porcellus
717147 Macaca mulatta
100971792 Pan paniscus
456880 Pan troglodytes
100395116 Callithrix jacchus
100620501 Sus scrofa
Fournisseurs de qualité sélectionnés pour PCSK9 (PCSK9) Kits ELISA
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