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Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) Kits ELISA

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. De plus, nous expédions PCSK9 Anticorps (152) et PCSK9 Protéines (61) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PCSK9 255738 Q8NBP7
PCSK9 100102 Q80W65
PCSK9 298296 P59996
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Top PCSK9 Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 66 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.11 ng/mL 0.45-30 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 9 to 12 Days
772,39 €
Détails
Souris 10pg/mL 62.5-4000 pg/mL Mouse PCSK9 PicoKine ELISA Kit standard curve 96 Tests Connectez-vous pour afficher 8 to 11 Days
507,05 €
Détails
Singe 1.1 pg/mL 1.1-800 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 9 to 12 Days
874,71 €
Détails
Rat 1.19 ng/mL 3.12-200 ng/mL 96 Tests Connectez-vous pour afficher 7 to 10 Days
804,23 €
Détails
Poulet 4.688 ng/mL 7.813-500 ng/mL   96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Lapin 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Porc 0.469 ng/mL 0.781-50 ng/mL   96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Cobaye 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Souris 94-6000 pg/mL   1 kit Connectez-vous pour afficher 8 to 9 Days
768,00 €
Détails
Chien
  96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails

PCSK9 Kits ELISA mieux référencés

  1. Mouse (Murine) PCSK9 Kit ELISA pour Sandwich ELISA - ABIN2685159 : Seidah, Benjannet, Wickham, Marcinkiewicz, Jasmin, Stifani, Basak, Prat, Chretien: The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation. dans Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 references for ABIN2685159

  2. Human PCSK9 Kit ELISA pour Sandwich ELISA - ABIN820112 : Dogan, Akman, Simsek, Ozdem, Comak, Gokceoglu, Kardelen, Koyun: Assessment of left ventricular function by tissue Doppler echocardiography in pediatric chronic kidney disease. dans Renal failure 2015 (PubMed)
    Show all 2 references for ABIN820112

Plus Kits ELISA pour PCSK9 partenaires d'interaction

Human Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. Low LDL cholesterol levels due to PCSK9 and HMGCR (Montrer HMGCR Kits ELISA) variants had no causal effect on high risk of Alzheimer's disease, vascular dementia, any dementia, or Parkinson's disease; however, low LDL cholesterol levels may have a causal effect in reducing the risk of Alzheimer's disease.

  2. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (Montrer CA2 Kits ELISA)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (Montrer LDLR Kits ELISA) degradation and promoting LDLR (Montrer LDLR Kits ELISA)-dependent hepatic cholesterol uptake.

  3. Even though LDLR (Montrer LDLR Kits ELISA)-R410S and LDLR (Montrer LDLR Kits ELISA)-WT were similar in levels of cell surface and total receptor and bound equally well to LDL or extracellular PCSK9, the LDLR (Montrer LDLR Kits ELISA)-R410S was resistant to exogenous PCSK9-mediated degradation in endosomes/lysosomes and showed reduced LDL internalization and degradation relative to LDLR (Montrer LDLR Kits ELISA)-WT.

  4. Lipid therapy today and tomorrow: anti-PCSK9

  5. First human antibodies were recently approved as the first immunotherapeutic agents for the treatment of severe hypercholesterolemia and in patients with statin intolerance. An additional PCSK9 antibody is presently being studied in phase III clinical trials.[review]

  6. Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to low-density lipoprotein (LDL) receptors leading to their degradation in the liver. Inhibition of PCSK9 leads to an increase in LDL receptors and as a result to a reduction of LDL cholesterol in blood. [review]

  7. Furthermore, the effect of reduction of LDL-C by proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition and by the cholesteryl ester transfer protein (CETP (Montrer CETP Kits ELISA)) inhibitor anacetrapib on cardiovascular events is currently being investigated in large clinical outcome study programs. [review]

  8. Further information on long-term efficacy, tolerability and cost-effectiveness of PCSK9 inhibition and possibilities of implementation in the healthcare system are awaited from ongoing clinical outcome trials, such as FOURIER, ODYSSEY OUTCOMES, SPIRE 1 (Montrer SPIRE1 Kits ELISA) and 2 involving more than 70,000 high-risk patients. [review]

  9. The 2 or 4week subcutaneous therapy with the recently approved antibodies alirocumab and evolocumab for inhibition of proprotein convertase subtilisin-kexin type 9 (PCSK9) reduces low-density lipoprotein cholesterol (LDL-C) in addition to statins and ezetimibe by 50-60 %. [review]

  10. study provides the first evidence that GPC3 (Montrer GPC3 Kits ELISA) can modulate the PCSK9 extracellular activity as a competitive binding partner to the LDLR (Montrer LDLR Kits ELISA) in HepG2 cells.

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (Montrer CA2 Kits ELISA)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (Montrer LDLR Kits ELISA) degradation and promoting LDLR (Montrer LDLR Kits ELISA)-dependent hepatic cholesterol uptake.

  2. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor (Montrer LDLR Kits ELISA) Degradation.

  3. PCSK9 increases hepatic lipid and lipoprotein production via apoE (Montrer APOE Kits ELISA)- and LDLR (Montrer LDLR Kits ELISA)-dependent mechanisms

  4. Podocyte damage triggers marked inductions in plasma PCSK9, and knockout of Pcsk9 ameliorates dyslipidemia in a mouse model of nephrotic syndrome.

  5. polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating PCSK9.

  6. binding of PCSK9 to GRP94 (Montrer HSP90B1 Kits ELISA) protects LDLR (Montrer LDLR Kits ELISA) from degradation likely by preventing early binding of PCSK9 to LDLR (Montrer LDLR Kits ELISA)

  7. The absence of PCSK9 results in a sex- and tissue-specific subcellular distribution of the LDLR (Montrer LDLR Kits ELISA) and VLDLR (Montrer VLDLR Kits ELISA), which is determined by estradiol levels.

  8. that ox-LDL receptor-1 (Montrer OLR1 Kits ELISA) and PCSK9 positively influence each other's expression, especially during an inflammatory reaction

  9. Data show that leptin (Montrer LEP Kits ELISA) treatment suppresses proprotein convertase subtilisin/kexin type 9 (PCSK9) in male, but fails to suppress PCSK9 in female.

  10. The Liver Clock Controls Cholesterol Homeostasis through Trib1 (Montrer TRIB1 Kits ELISA) Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR (Montrer LDLR Kits ELISA)) Axis.

PCSK9 profil antigène

Antigen Summary

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Gene names and symbols associated with PCSK9

  • proprotein convertase subtilisin/kexin type 9 (pcsk9) anticorps
  • proprotein convertase subtilisin/kexin type 9 (PCSK9) anticorps
  • proprotein convertase subtilisin/kexin type 9 (Pcsk9) anticorps
  • proprotein convertase subtilisin/kexin type 9-like (LOC100620501) anticorps
  • AI415265 anticorps
  • AI747682 anticorps
  • FH3 anticorps
  • HCHOLA3 anticorps
  • LDLCQ1 anticorps
  • NARC-1 anticorps
  • Narc1 anticorps
  • PC9 anticorps

Protein level used designations for PCSK9

proprotein convertase subtilisin/kexin type 9 , convertase subtilisin/kexin type 9 preproprotein , neural apoptosis regulated convertase 1 , subtilisin/kexin-like protease PC9 , NARC-1 , convertase subtilisin , neural apoptosis-regulated convertase 1 , proprotein convertase 9 , proprotein convertase PC9 , proprotein convertase subtilisin/kexin type 9 preproprotein , Proprotein convertase 9 , Subtilisin/kexin-like protease PC9

GENE ID SPECIES
495509 Xenopus laevis
100150316 Danio rerio
100544916 Meleagris gallopavo
255738 Homo sapiens
100102 Mus musculus
298296 Rattus norvegicus
424664 Gallus gallus
100731533 Cavia porcellus
717147 Macaca mulatta
100971792 Pan paniscus
456880 Pan troglodytes
100395116 Callithrix jacchus
100620501 Sus scrofa
Fournisseurs de qualité sélectionnés pour PCSK9 (PCSK9) Kits ELISA
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