Protease, serine, 12 (Neurotrypsin, Motopsin) Protéines (PRSS12)

PRSS12 encodes a member of the trypsin family of serine proteases. De plus, nous expédions Protease, serine, 12 (Neurotrypsin, Motopsin) Anticorps (30) et Protease, serine, 12 (Neurotrypsin, Motopsin) Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PRSS12 8492 P56730
PRSS12 19142 O08762
PRSS12 85266 G3V801
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Top Protease, serine, 12 (Neurotrypsin, Motopsin) Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$11,073.30
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$11,073.30
Détails
Escherichia coli (E. coli) Souris His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$701.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$405.71
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$4,163.50
Détails
Escherichia coli (E. coli) Humain T7 tag,His tag   100 μg Connectez-vous pour afficher 15 to 18 Days
$704.00
Détails

PRSS12 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Plus protéines pour Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) partenaires d'interaction

Human Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) interaction partners

  1. 4-base pair deletion in the neurotrypsin gene was associated with autosomal recessive nonsyndromic mental retardation; findings suggest that neurotrypsin-mediated proteolysis is required for normal synaptic function

Mouse (Murine) Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) interaction partners

  1. This study identifies Tequila and neurotrypsin as new genes repressed by presenilins and reveals a novel mechanism used by presenilins to modulate CREB (Montrer CREB1 Protéines) signaling based on controlling CREB (Montrer CREB1 Protéines) recruitment.

  2. co-expression of sez-6 with motopsin restored the effect of motopsin at the basal level, while sez-6 expression alone showed no effects on cell morphology. Our results suggest that the interaction of motopsin and sez-6 modulates neuronal cell morphology

  3. Our results indicate that an extracellular protease, motopsin, preferentially affects social behaviors, and modulates the functions of hippocampal neurons.

  4. motopsin has multiple functions, such as axon outgrowth, arranging perineuronal environment, and maintaining neuronal plasticity, partly in coordination with other proteases including tissue plasminogen activator (Montrer PLAT Protéines).

  5. neurotrypsin exclusively cleaves glycanated variants of agrin (Montrer AGRN Protéines); neurotrypsin-dependent cleavage of agrin (Montrer AGRN Protéines) was concentrated at synapses, where the most heavily glycanated variants of agrin (Montrer AGRN Protéines) predominate

  6. Detailed analyses indicated that presynaptic action potential firing is necessary for the release of neurotrypsin, whereas postsynaptic NMDA receptor activation is necessary for the neurotrypsin-dependent cleavage of agrin (Montrer AGRN Protéines).

Profil protéine Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12)

Profil protéine

This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1).

Gene names and symbols associated with PRSS12

  • protease, serine 12 (PRSS12)
  • 26S proteasome regulatory SU (prsS12)
  • prsS12 (HAN_3g451)
  • neurotrypsin (CpipJ_CPIJ005457)
  • neurotrypsin (CpipJ_CPIJ005852)
  • protease, serine 12 neurotrypsin (motopsin) (Prss12)
  • protease, serine 12 (Prss12)
  • Bssp-3 Protéine
  • BSSP3 Protéine
  • motopsin Protéine
  • MRT1 Protéine
  • Nt Protéine
  • PRSS12 Protéine

Protein level used designations for PRSS12

protease, serine, 12 (neurotrypsin, motopsin) , 26S proteasome regulatory SU , prsS12 , neurotrypsin , brain-specific serine protease 3 , leydin , serine protease 12 , peptidase, serine, 12 (neurotrypsin, motopsin)

GENE ID SPECIES
422685 Gallus gallus
512034 Bos taurus
857479 Guillardia theta
5739504 Hemiselmis andersenii
6037525 Culex quinquefasciatus
6037801 Culex quinquefasciatus
10447290 Cryptomonas paramecium
100353449 Oryctolagus cuniculus
100524882 Sus scrofa
8492 Homo sapiens
704461 Macaca mulatta
471291 Pan troglodytes
19142 Mus musculus
85266 Rattus norvegicus
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