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anti-Protein Kinase D2 (PKD2) Anticorps

The protein encoded by PKD2 belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. De plus, nous expédions PKD2 Kits (11) et PKD2 Protéines (11) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PKD2 5311 Q13563
PKD2 101540 Q8BZ03
PKD2 292658 Q5XIS9
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Top anti-PKD2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 125 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué IP, WB Detection of human PKD2 by Western blot and immunoprecipitation.  Western blot run on 30 ug of HEK293 whole cell lysate that were either untreated or transfected with expression constructs for PKD1 and PKD3 as controls for reactivity with these homologs using ABIN152061. Antibodies for IP were used at 0.01 ug/ug of lysate.  IP was detected by Western using NB 100-637.  10 second ECL exposure. Western Blot: Protein Kinase D2 Antibody [ABIN152061] - Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PKD2 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
385,00 €
Détails
Humain Lapin Inconjugué IHC (p), ELISA, WB Human Brain Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Human Brain Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
583,00 €
Détails
Humain Souris Inconjugué FACS, WB HEK293T cells transfected with either RC215335 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PRKD2 antibody (ABIN2453510), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PRKD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PRKD2. 100 μL Connectez-vous pour afficher 6 to 8 Days
366,67 €
Détails
Humain Souris Inconjugué FACS, IF, WB Anti-PRKD2 mouse monoclonal antibody (ABIN2453513) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PRKD2 (RC215335). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PRKD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PRKD2. 100 μL Connectez-vous pour afficher 6 to 8 Days
366,67 €
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PRKD2 mouse monoclonal antibody. (ABIN2453511, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PRKD2 mouse monoclonal antibody. (ABIN2453511, Dilution 1:50) 100 μL Connectez-vous pour afficher 6 to 8 Days
366,67 €
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PRKD2 mouse monoclonal antibody. (ABIN2453512, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PRKD2 mouse monoclonal antibody. (ABIN2453512, Dilution 1:50) 100 μL Connectez-vous pour afficher 6 to 8 Days
366,67 €
Détails

PKD2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , ,
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Mouse (Murine)


Rat (Rattus)
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anti-PKD2 Anticorps mieux référencés

  1. Human Polyclonal PKD2 Primary Antibody pour IP, WB - ABIN152061 : Liu, Evans, Britton, Zachary: The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis. dans Oncogene 2008 (PubMed)
    Show all 8 references for ABIN152061

  2. Human Polyclonal PKD2 Primary Antibody pour EIA, IHC (p) - ABIN360330 : Stayner, Zhou: Polycystin channels and kidney disease. dans Trends in pharmacological sciences 2001 (PubMed)
    Show all 5 references for ABIN360330

Plus d’anticorps contre PKD2 partenaires d’interaction

Human Protein Kinase D2 (PKD2) interaction partners

  1. Novel PKD2 mutations in Chinese autosomal dominant polycystic kidney disease patients

  2. Two neutral missense PKD2 variants indentified in exon1 c.83G>C (p.R28P) and c.568G>A (p.A190T), which the former segregate with the mutation in affected relatives, and two new intronic and 3'UTR (Montrer UTS2R Anticorps) variants, c.1548+63C>T and c.*363delA.

  3. this study presents the cryo-EM structure of PKD2 in lipid bilayers at 3.0 A resolution, which establishes PKD2 as a homotetrameric ion channel and provides insight into potential mechanisms for its activation.

  4. PCs expression and p53 (Montrer TP53 Anticorps) activation as a regulator of cell proliferation were further evaluated in vivo and in 69 advanced human carotid atherosclerotic plaques.

  5. PKD2 and RSK1 (Montrer RPS6KA1 Anticorps) regulate integrin beta4 phosphorylation at threonine 1736 to stabilize keratinocyte cell adhesion and its hemidesmosomes.

  6. The coiled-coil domain in the PC2 (Montrer KRT6B Anticorps) C-terminal forms a stable helix bundle regardless of the presence of Ca(2 (Montrer CA2 Anticorps)+).

  7. Results show that some of the previously reported missense or synonymous mutations in PKD2 gene caused altered pre-mRNA splicing.

  8. PKD2 is a core factor in the formation of this multiprotein complex at the TGN (Montrer TG Anticorps) that controls constitutive secretion of matrix metalloproteinase (Montrer MMP20 Anticorps) cargo.

  9. Human polycystin-2 transgene dose-dependently rescues autosomal-dominant polycystic kidney disease phenotypes in Pkd2 mutant mice

  10. FLNA (Montrer FLNA Anticorps) anchors PC2 (Montrer KRT6B Anticorps) to the actin cytoskeleton through complex PC2 (Montrer KRT6B Anticorps)-FLNA (Montrer FLNA Anticorps)-actin to reduce degradation and increase stability, and possibly regulate PC2 (Montrer KRT6B Anticorps) function in a Ca-dependent manner.

Mouse (Murine) Protein Kinase D2 (PKD2) interaction partners

  1. Our studies demonstrate that PKD1 (Montrer PKD1 Anticorps)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (Montrer DGKA Anticorps) effect on MVB secretory traffic.

  2. Results reveal that whereas protein kinase D1 (Montrer PRKD1 Anticorps) and protein kinase D2 are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  3. PKD2 acted as an amplification checkpoint for antigen-stimulated digital cytokine responses and translated the differential strength of TCR signaling to determine the number of naive CD8 (Montrer CD8A Anticorps)(+) T cells that became effector cells.

  4. Protein kinase D2 promotes in vitro osteoclast differentiation and fusion

  5. A bioinformatic screen identified the serine-threonine kinase (Montrer CDK4 Anticorps) protein kinase D2 (PRKD2) as a potential effector of GABP in hematopoietic stem cells

  6. Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by alpha/beta mature TCR complexes in peripheral T-cells.

  7. PKD2 is a common signaling target downstream of various agonist receptors in platelets and G(q)-mediated signals along with calcium and novel PKC (Montrer PKC Anticorps) isoforms, in particular, PKCdelta (Montrer PKCd Anticorps) activate PKD2 in platelets.

  8. Data demonstrate that, unlike PKD1 (Montrer PKD1 Anticorps), PKD2 catalytic activity is dispensable for normal embryogenesis.

  9. PKD2, like PKD (Montrer PRKD1 Anticorps), facilitates mitogenesis in 3T3 cells

PKD2 profil antigène

Profil protéine

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with anti-Protein Kinase D2 (PKD2) Anticorps

  • protein kinase D2 (PRKD2) anticorps
  • polycystic kidney disease 2 (autosomal dominant) (PKD2) anticorps
  • protein kinase D2 (Prkd2) anticorps
  • AI325941 anticorps
  • APKD2 anticorps
  • nPKC-D2 anticorps
  • Pc-2 anticorps
  • PC2 anticorps
  • PKD2 anticorps
  • PKD4 anticorps
  • PRKD2 anticorps
  • RGD1308054 anticorps
  • TRPP2 anticorps

Protein level used designations for anti-Protein Kinase D2 (PKD2) Anticorps

protein kinase D2 , serine/threonine-protein kinase D2-like , R48321 , autosomal dominant polycystic kidney disease type II protein , polycystin-2 , polycystwin , transient receptor potential cation channel, subfamily P, member 2 , serine/threonine-protein kinase D2 , nPKC-D2

GENE ID SPECIES
468929 Pan troglodytes
782793 Bos taurus
100407181 Callithrix jacchus
100471375 Ailuropoda melanoleuca
5311 Homo sapiens
25865 Homo sapiens
101540 Mus musculus
292658 Rattus norvegicus
484427 Canis lupus familiaris
100517036 Sus scrofa
100355908 Oryctolagus cuniculus
100717067 Cavia porcellus
Fournisseurs de qualité sélectionnés pour anti-PKD2 (PKD2) Anticorps
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