Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) Kits ELISA

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). De plus, nous expédions Protein Phosphatase 4, Regulatory Subunit 2 Anticorps (44) et Protein Phosphatase 4, Regulatory Subunit 2 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain PPP4R2 PPP4R2 151987 Q9NY27
Anti-Souris PPP4R2 PPP4R2 232314 Q0VGB7
Anti-Rat PPP4R2 PPP4R2 297486  
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Plus Kits ELISA pour Protein Phosphatase 4, Regulatory Subunit 2 partenaires d'interaction

Human Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) interaction partners

  1. PPP4R2 affects the survival of neuronal cells in response to DNA damage.

  2. PP4R2, a regulatory subunit of PP4 (Montrer ANXA5 Kits ELISA), mediates the DNA damage-dependent association between RPA2 (Montrer RPA2 Kits ELISA) and the PP4C (Montrer PPP4C Kits ELISA) catalytic subunit.

  3. A three-protein PP4 phosphatase complex in mammalian cells, containing PP4C, PP4R2, and PP4R3beta, specifically dephosphorylates ATR-mediated gamma-H2AX generated during DNA replication.

Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) profil antigène

Antigen Summary

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage- dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).

Gene names and symbols associated with PPP4R2

  • protein phosphatase 4, regulatory subunit 2a (ppp4r2a) anticorps
  • Serine/threonine-protein phosphatase 4 regulatory subunit 2 (ppp4r2) anticorps
  • protein phosphatase 4, regulatory subunit 2 (PPP4R2) anticorps
  • protein phosphatase 4, regulatory subunit 2 (Ppp4r2) anticorps
  • BE691708 anticorps
  • C230060M08Rik anticorps
  • fe11b04 anticorps
  • PP4R2 anticorps
  • ppp4r2 anticorps
  • wu:fe11b04 anticorps

Protein level used designations for PPP4R2

serine/threonine-protein phosphatase 4 regulatory subunit 2-A , protein phosphatase 4, regulatory subunit 2 , serine/threonine-protein phosphatase 4 regulatory subunit 2

GENE ID SPECIES
326723 Danio rerio
496569 Xenopus (Silurana) tropicalis
693479 Macaca mulatta
151987 Homo sapiens
232314 Mus musculus
297486 Rattus norvegicus
416098 Gallus gallus
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