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Protein tyrosine Phosphatase, Receptor Type, O (PTPRO) Kits ELISA

PTPRO encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. De plus, nous expédions Protein tyrosine Phosphatase, Receptor Type, O Protéines (11) et Protein tyrosine Phosphatase, Receptor Type, O Anticorps (10) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PTPRO 50677  
PTPRO 19277 E9Q612
PTPRO 5800 Q16827
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Top Protein tyrosine Phosphatase, Receptor Type, O Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 19 products:

Catalogue No. Reactivité Sensibilité Gamme Quantité Fournisseur Livraison Prix Détails
Souris 0.469 ng/mL 0.781-50 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
600,00 €
Détails
Humain 0.188 ng/mL 0.313-20 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
600,00 €
Détails
Rat 0.938 ng/mL 1.563-100 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
600,00 €
Détails
Porc 0.188 ng/mL 0.313-20 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Cobaye 1.875 ng/mL 3.125-200 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Lapin 9.375 ng/mL 15.625-1000 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Poulet 9.375 ng/mL 15.625-1000 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Singe 0.188 ng/mL 0.313-20 ng/mL 96 Tests Connectez-vous pour afficher 6 to 8 Days
666,67 €
Détails
Mouton 0.1 ng/mL 1.0-25 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Chien 0.1 ng/mL 1.0-25 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails

Plus Kits ELISA pour Protein tyrosine Phosphatase, Receptor Type, O partenaires d'interaction

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, O (PTPRO) interaction partners

  1. PTPRO plays an important role in FH by interacting with TLR4 (Montrer TLR4 Kits ELISA).

  2. Study show that EphA4 (Montrer EPHA4 Kits ELISA) is a substrate for PTP-oc in osteoclasts and that the molecular mechanism contributing to the PTP-oc-induced up-regulation of the osteoclast activity in part involves its dephosphorylation and inactivation of the EphA4 (Montrer EPHA4 Kits ELISA) signaling.

  3. PTPRO truncated serves as an important tumor suppressor in hepatocellular carcinoma microenvironment.

  4. The loss of PTPRO in the tumor niche was correlated with larger tumor volume, more metastases, increased number of circulating tumor cells, less apoptosis and reduced necrosis rates in the orthotopic mouse model of breast cancer.

  5. PTPRO regulates insulin (Montrer INS Kits ELISA) and lipid metabolism via the PI3K/Akt (Montrer AKT1 Kits ELISA)/MDM4 (Montrer MDM4 Kits ELISA)/MDM2 (Montrer MDM2 Kits ELISA)/P53 (Montrer TP53 Kits ELISA) axis by affecting autophagy.

  6. Survival and inflammation promotion effect of PTPRO in fulminant hepatitis is associated with NF-kappaB ac (Montrer CTNNB1 Kits ELISA)tivation.

  7. PTPRO deficiency resulted in reduction of NF-kappaB activation in both hepatocytes and macrophages and was correlated to c-Src phosphorylation.

  8. PTPRO is expressed mainly in TrkB (Montrer NTRK2 Kits ELISA)-expressing (TrkB (Montrer NTRK2 Kits ELISA)(+)) and Ret (Montrer RET Kits ELISA)(+) mechanoreceptors within the trigeminal ganglia during embryogenesis.

  9. These results suggest that ptpro is a target gene of Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) signaling and that PTPRO may function as a novel receptor for Wnt (Montrer WNT2 Kits ELISA).

  10. Data indicate that PTPRO is required for peptidergic differentiation and process outgrowth of sensory neurons, as well as mature sensory function, and provide the first evidence that RPTPs regulate DRG development.

Human Protein tyrosine Phosphatase, Receptor Type, O (PTPRO) interaction partners

  1. PTPRO truncated serves as an important tumor suppressor in hepatocellular carcinoma microenvironment.

  2. These observations confirm that PTPRO plays a critical role in liver fibrogenesis by affecting PDGF (Montrer PDGFA Kits ELISA) signaling in HSC (Montrer FUT1 Kits ELISA) activation and might be developed into a feasible therapeutic approach for the treatment of chronic fibrotic liver diseases.

  3. The optimal pH value of PTP-oc is approximately 7.0.

  4. Loss of PTPRO expression is associated with chronic lymphocytic leukemia.

  5. Results highlight the PTPRO contribution in negative regulation of SRC (Montrer SRC Kits ELISA)/EGFR (Montrer EGFR Kits ELISA) signaling in colon cancer.

  6. PTPRO was drastically decreased in fulminant hepatitis, and this was associated with enhanced beta-catenin (Montrer CTNNB1 Kits ELISA) accumulation but reduced IFN-gamma (Montrer IFNG Kits ELISA) secretion.

  7. Our study suggests an interesting PTPRO/TLR4 (Montrer TLR4 Kits ELISA)/NF-kappaB (Montrer NFKB1 Kits ELISA) signaling feedback loop in Hhepatocellular carcinomcarcinogenesis and progression

  8. PTPRO level was decreased in the early phase but reversed in the late phase of hepatic ischemia reperfusion injury.

  9. PTPRO methylation is associated with poor survival only in HER2 (Montrer ERBB2 Kits ELISA)-positive patients.

  10. methylation and downregulation of PTPRO in a subset of primary human HCC (Montrer FAM126A Kits ELISA) and establish VCP (Montrer vcp Kits ELISA) as a novel functionally important substrate of this tyrosine phosphatase that could be a potential molecular target for HCC (Montrer FAM126A Kits ELISA) therapy.

Protein tyrosine Phosphatase, Receptor Type, O (PTPRO) profil antigène

Antigen Summary

This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.

Gene names and symbols associated with PTPRO

  • receptor-type tyrosine-protein phosphatase-like (PTP) anticorps
  • protein tyrosine phosphatase, receptor type, O (Ptpro) anticorps
  • protein tyrosine phosphatase, receptor type, O (PTPRO) anticorps
  • D28 anticorps
  • GLEPP1 anticorps
  • NPHS6 anticorps
  • PTP-OC anticorps
  • PTP-U2 anticorps
  • PTPBK anticorps
  • Ptpn15 anticorps
  • PTPoc anticorps
  • PTPphi anticorps
  • PTPROT anticorps
  • PTPU2 anticorps
  • R-PTP-O anticorps
  • RPTP-BK anticorps

Protein level used designations for PTPRO

glomerular epithelial protein 1 , osteoclastic phosphotyrosyl phosphatase , Glomerular epithelial protein 1 , receptor-type protein tyrosine phosphatase D30 , receptor-type tyrosine-protein phosphatase O , PTPase U2 , protein tyrosine phosphatase U2 , protein tyrosine phosphatase, non-receptor type 15 , receptor protein tyrosine phosphatase RO , PTP phi , osteoclastic transmembrane protein-tyrosine phosphatase , phosphotyrosine phosphatase U2 , protein tyrosine phosphatase PTP-U2

GENE ID SPECIES
100009529 Oryctolagus cuniculus
50677 Rattus norvegicus
19277 Mus musculus
5800 Homo sapiens
100714951 Cavia porcellus
100524563 Sus scrofa
486664 Canis lupus familiaris
541043 Bos taurus
373911 Gallus gallus
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