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The protein encoded by RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. De plus, nous expédions RAB8A Protéines (17) et RAB8A Kits (7) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 86 products:
Dog (Canine) Monoclonal RAB8A Primary Antibody pour IF, IP - ABIN968210
Bahadoran, Aberdam, Mantoux, Buscà, Bille, Yalman, de Saint-Basile, Casaroli-Marano, Ortonne, Ballotti: Rab27a: A key to melanosome transport in human melanocytes. dans The Journal of cell biology 2001
Show all 5 references for ABIN968210
Human Polyclonal RAB8A Primary Antibody pour FACS, IHC (p) - ABIN1881723
Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: Construction of a human full-length cDNA bank. dans Gene 1995
Show all 2 references for ABIN1881723
Cow (Bovine) Polyclonal RAB8A Primary Antibody pour ELISA, WB - ABIN374945
Yoshimura, Egerer, Fuchs, Haas, Barr: Functional dissection of Rab GTPases involved in primary cilium formation. dans The Journal of cell biology 2007
Chicken Polyclonal RAB8A Primary Antibody pour WB - ABIN2792290
Roland, Kenworthy, Peranen, Caplan, Goldenring: Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. dans Molecular biology of the cell 2007
Rab8 can induce Rac1- and Tiam1 (Montrer TIAM1 Anticorps)-dependent cortical actin polymerization and focal adhesion disassembly through the proteases MT1-MMP (Montrer MMP14 Anticorps) and calpain, and Rho-GTPase (Montrer RACGAP1 Anticorps)-dependent mechanisms
Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (Montrer BIN1 Anticorps)-dynamin (Montrer DNM1 Anticorps) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.
Further exploration of the NINL (Montrer NINL Anticorps)-associated interactome identifies MICAL3, a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.
The small GTPase (Montrer RACGAP1 Anticorps) Rab8 interacts with VAMP-3 (Montrer VAMP3 Anticorps) to regulate the delivery of recycling T-cell receptors to the immune synapse.
the role of Rabin8 (Montrer RAB3IP Anticorps) (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.
DLC3 (Montrer STARD8 Anticorps) is recruited to Rab8-positive membrane tubules and is required for the integrity of the Rab8 and Golgi compartments.
Rab8A GTPase (Montrer RACGAP1 Anticorps) Ser (Montrer SIGLEC1 Anticorps)(111) phosphorylation is not directly regulated by PINK1 (Montrer PINK1 Anticorps) in vitro and demonstrate in cells the time course of Ser (Montrer SIGLEC1 Anticorps)(111) phosphorylation of Rab8A, 8B and 13 is markedly delayed compared to phosphorylation of Parkin (Montrer PARK2 Anticorps) at Ser (Montrer SIGLEC1 Anticorps)(65).
Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.
High expression of RAB8A is associated with endometrial cancer.
Study established a direct interaction between alpha-synclein and Rab8a and provided unique insights into the molecular mechanisms of alpha-synclein toxicity
Cc2d2a (Montrer CC2D2A Anticorps), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.
Data show that elipsa (Montrer TRAF3IP1 Anticorps) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (Montrer RACGAP1 Anticorps), known to localize to cilia.
Results highlight a novel role of Rab8, downstream of IFT20, in the pathway that regulates T cell receptor (TCR) recycling, through recruiting VAMP-3 and promoting the fusion with the synaptic membrane of endosomes carrying TCR cargoes.
Rab8a thus controls Wnt (Montrer WNT2 Anticorps) delivery in producing cells and is crucial for Paneth cell maturation.
Rab8a acts as an activator of Fsp27 (Montrer CIDEC Anticorps)-mediated LD fusion and growth.
Simultaneous loss of Rab8a and Rab8b (Montrer RAB8B Anticorps) has little effect on ciliogenesis, whereas additional loss of Rab10 (Montrer RAB10 Anticorps) greatly affects ciliogenesis.
acidosis-induced NBCe1 (Montrer SLC4A4 Anticorps)-A, but not NBCe1 (Montrer SLC4A4 Anticorps)-B/C, trafficking is mediated by Rab8a.
AS160 (Montrer TBC1D4 Anticorps) and Rab8a regulate membrane recruitment of CD36 (Montrer CD36 Anticorps).
Cdc42 (Montrer CDC42 Anticorps) and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice
Rab8a colocalizes with IL-1b (Montrer IL1B Anticorps) and LC3 (Montrer MAP1LC3A Anticorps) and controls IL-1b (Montrer IL1B Anticorps) secretion
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
, hematopoietic SH2 domain containing
, ras-related protein Rab-8A
, RAB8A, member RAS oncogene family
, member RAS oncogene family
, Ras-related protein Rab-8A
, mel transforming oncogene (RAB8 homolog)
, mel transforming oncogene (derived from cell line NK14)
, mel transforming oncogene (derived from cell line NK14)- RAB8 homolog
, oncogene c-mel
, ras-associated protein RAB8
, RAB8, member RAS oncogene family
, cell line NK14 derived transforming oncogene