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RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Kits ELISA

The protein encoded by RASA1 is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. De plus, nous expédions RASA1 Anticorps (97) et RASA1 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
RASA1 5921 P20936
RASA1 25676 P50904
RASA1 218397  
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Top RASA1 Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Quantité Fournisseur Livraison Prix Détails
Lapin 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Humain 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Rat 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Souris 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Cobaye 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Singe 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Chien 0.1 ng/mL 0.5-10 ng/mL 96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Porc
96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
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Mouton
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Boeuf (Vache)
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Plus Kits ELISA pour RASA1 partenaires d'interaction

Human RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. Data show that patients with low level of Ras GTPase-activating protein 1 (RASA1) expression correlated with a significantly poorer survival compared to those with high level of RASA1 expression.

  2. Results show that oncogenic KRAS can activate Rho through miR-31-mediated regulation of RASA1 indicating miR-31 acts as a KRAS effector to modulate invasion and migration in pancreatic cancer.

  3. PTP1B (Montrer PTPN1 Kits ELISA) dephosphorylates PITX1 (Montrer PITX1 Kits ELISA) to weaken its protein stability and the transcriptional activity for p120RasGAP gene expression

  4. Data suggest that, in response to netrin-1 (Montrer NTN1 Kits ELISA)/netrin receptor (DCC (Montrer DCC Kits ELISA)) signaling, p120RasGAP is recruited to growth cones and supports axon outgrowth; p120RasGAP Src (Montrer SRC Kits ELISA) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  5. Maternal and fetal capillary malformation-arteriovenous malformation due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis have been found.

  6. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ (Montrer GNAQ Kits ELISA) is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 disorders.

  7. Data showed that hypoxia regulated the expression of miR (Montrer MLXIP Kits ELISA)-182 and RASA1 to promote HCC (Montrer FAM126A Kits ELISA) angiogenesis.

  8. p120RasGAP shields Akt (Montrer AKT1 Kits ELISA) from deactivating phosphatases in FGF1 (Montrer FGF1 Kits ELISA) signaling, but loses this ability once cleaved by caspase-3 (Montrer CASP3 Kits ELISA).

  9. Capillary malformation-arteriovenous malformation syndrome (CM-AVM) is an autosomal dominant disorder caused by RASA1 mutations.

  10. Multifocal, small, round-to-oval, pinkish-to-red cutaneous capillary malformations are seen in more than 90% of people with RASA1 mutations.

Cow (Bovine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. The data suggest that nitrosylation of H-Ras (Montrer HRAS Kits ELISA) rearranges the adsorptive potential and intrinsic GTPase (Montrer RACGAP1 Kits ELISA) activity of H-Ras (Montrer HRAS Kits ELISA) through modification of C-terminal cysteines of molecule.

Mouse (Murine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. Double-deficient RASA1-neurofibromin 1 (Montrer NF1 Kits ELISA) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (Montrer NOTCH1 Kits ELISA) gene.

  2. Rasa1 may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  3. Regulation of Rasa1 translation by miR (Montrer MLXIP Kits ELISA)-132 was seen in severed axons, demonstrating local function within the axon.

  4. RASA1 mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS subject and in the animal model.

  5. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 GTPase activating protein 1 (RASA1)

  6. 14-3-3 (Montrer YWHAQ Kits ELISA) negatively regulates the RGC downstream of the PI3-kinase (Montrer PIK3CA Kits ELISA)/Akt (Montrer AKT1 Kits ELISA) signaling pathway

  7. Caspase-3 (Montrer CASP3 Kits ELISA) is a stress intensity sensor that controls cell fate by either initiating a RasGAP cleavage-dependent cell resistance program or a cell suicide response mediated by akt (Montrer AKT1 Kits ELISA).

  8. Data reveal a role for RASA1 as a physiological negative regulator of lymphatic endothelial cell growth that maintains the lymphatic vasculature in a quiescent functional state through its ability to inhibit Ras signal transduction.

  9. Ca2 (Montrer CA2 Kits ELISA)+-dependent monomer and dimer formation switches CAPRI (Montrer RASA4 Kits ELISA) Protein between Ras GTPase-activating protein (GAP) and RapGAP (Montrer RAP1GAP Kits ELISA) activities

  10. statins inhibit GGPP biosynthesis in the mevalonate pathway, and then inhibit signal transduction in the Ras/ERK (Montrer EPHB2 Kits ELISA) and Ras/Akt (Montrer AKT1 Kits ELISA) pathways, thereby inhibiting bFGF (Montrer FGF2 Kits ELISA), HGF (Montrer HGF Kits ELISA), TGF-beta (Montrer TGFB1 Kits ELISA) expression

RASA1 profil antigène

Antigen Summary

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Gene names and symbols associated with RASA1

  • vacuolar peduncle (vap) anticorps
  • RAS p21 protein activator (GTPase activating protein) 1 (RASA1) anticorps
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) anticorps
  • RAS p21 protein activator 1 (Rasa1) anticorps
  • CG9209 anticorps
  • CM-AVM anticorps
  • CMAVM anticorps
  • D-RasGAP anticorps
  • Dmel\\CG9209 anticorps
  • Gap anticorps
  • GAPX anticorps
  • p120GAP anticorps
  • p120RASGAP anticorps
  • PKWS anticorps
  • RAS-GAP anticorps
  • Rasa anticorps
  • RASGAP anticorps

Protein level used designations for RASA1

CG9209-PA , CG9209-PB , CG9209-PC , CG9209-PD , Ras GTPase-activating protein , vacuolar peduncule , vacuolar pedunculi , vap-PA , vap-PB , vap-PC , vap-PD , ras GTPase-activating protein 1 , triphosphatase-activating protein , GAP , GTPase-activating protein , RAS p21 protein activator (GTPase activating protein RAS p21) , p120GAP , rasGAP , RAS p21 protein activator 1 , p120-rasGAP

GENE ID SPECIES
32569 Drosophila melanogaster
5921 Homo sapiens
282032 Bos taurus
25676 Rattus norvegicus
427327 Gallus gallus
479158 Canis lupus familiaris
100627579 Sus scrofa
218397 Mus musculus
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