Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Kits ELISA

RASSF1 encodes a protein similar to the RAS effector proteins. De plus, nous expédions Ras Association (RalGDS/AF-6) Domain Family Member 1 Anticorps (140) et Ras Association (RalGDS/AF-6) Domain Family Member 1 Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
RASSF1 11186 Q9NS23
RASSF1 56289 Q99MK9
Anti-Rat RASSF1 RASSF1 363140  
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.059 ng/mL 0.15-10 ng/mL 96 Tests Connectez-vous pour afficher 11 to 15 Days
592,59 €
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  96 Tests Connectez-vous pour afficher 13 to 17 Days
788,70 €
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Plus Kits ELISA pour Ras Association (RalGDS/AF-6) Domain Family Member 1 partenaires d'interaction

Human Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) interaction partners

  1. Data suggest that the overexpression of DNMT3B4 may play an important role in human kidney tumorigenesis through chromosomal instability and methylation of RASSF1A.

  2. Methylation status of the RASSF1A gene promoter was strongly related to melanoma susceptibility but no significant difference was found between RASSF1A gene promoter methylation and the prognosis and clinical-pathological features of melanoma.

  3. In response to TGF-beta (Montrer TGFB1 Kits ELISA), RASSF1A is recruited to TGF-beta (Montrer TGFB1 Kits ELISA) receptor I and targeted for degradation by the co-recruited E3 ubiquitin ligase ITCH. RASSF1A degradation is necessary to permit Hippo pathway effector YAP1 (Montrer YAP1 Kits ELISA) association with SMADs and subsequent nuclear translocation of receptor-activated SMAD2 (Montrer SMAD2 Kits ELISA).

  4. Our results suggest a multifactorial role of RASSF1A in suppression of liver carcinogenesis

  5. For the first time, we performed analysis of DNA methylation (Montrer HELLS Kits ELISA) in SMARCB1/INI1 (Montrer SMARCB1 Kits ELISA)-deficient sinonasal carcinomas, reporting on significantly higher methylation of RASSF1 gene in this neoplasm.

  6. High methylation in the RASSF1A promoter region is associated with lung cancer.

  7. GSTP1 (Montrer GSTP1 Kits ELISA), APC (Montrer APC Kits ELISA) and RASSF1 gene methylation in prostate cancer samples: comparative analysis of MS-HRM method and Infinium HumanMethylation450 BeadChip beadchiparray diagnostic value

  8. Compared with adjacent normal tissues, the methylation frequencies of WIF-1 (Montrer WIF1 Kits ELISA), RASSF1A, and CDH13 (Montrer CDH13 Kits ELISA) genes were significantly higher but the mRNA levels of these 3 genes were significantly lower in EC tissues. The survival rates of patients with WIF-1 (Montrer WIF1 Kits ELISA), RASSF1A, and CDH13 (Montrer CDH13 Kits ELISA) methylations were significantly lower than those of patients without methylation

  9. The presence of higher RASSF1A methylation levels in fine-needle aspiration cytology specimens of nodular goitre may be useful in the assessment of oncological risk.

  10. this meta-analysis demonstrated that RASSF1A promoter methylation is significantly associated with increased risk of renal cell cancer

Mouse (Murine) Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) interaction partners

  1. essential role of RASSF1A in regulating TNF-alpha (Montrer TNF Kits ELISA) signalling in cardiomyocytes, with RASSF1A being key in the formation of the TNFR (Montrer TNFRSF1A Kits ELISA) complex and in signal transmission to the downstream targets

  2. RASSF1A may function to interfere and restrict TLR-driven activation of NF-kappaB (Montrer NFKB1 Kits ELISA) and is essential for protection against inflammation-induced injury.

  3. nickel-smelting fumes upregulated the expression of RASSF1A. This suggest that nickel-smelting fumes could be toxic to cells, inducing cell apoptosis and necrosis.

  4. Loss of RASSF1A synergizes with deregulated RUNX2 (Montrer RUNX2 Kits ELISA) signaling in tumorigenesis.

  5. Concomitant with the loss of Rassf1a, the loss of p53 (Montrer TP53 Kits ELISA) (which causes unrestrained propagation of tetraploids into aneuploid cells) further undermines genomic stability and accelerates tumorigenesis.

  6. Data show that methylation of CCND-2 (Montrer CCND2 Kits ELISA), p16, RAR-beta (Montrer RARB Kits ELISA) and RASSF-1a was significantly more prevalent in tumor than in normal tissue specimens.

  7. Rassf1A acts as a tumor suppressor gene.

  8. cooperation between inactivation of Rassf1a and Apc (Montrer APC Kits ELISA) resulting in accelerated intestinal tumourigenesis.

  9. RASSF1A mediates p21Cip1/Waf1 (Montrer CDKN1A Kits ELISA)-dependent cell cycle arrest and senescence through modulation of the Raf (Montrer RAF1 Kits ELISA)-MEK (Montrer MDK Kits ELISA)-ERK (Montrer EPHB2 Kits ELISA) pathway and inhibition of Akt (Montrer AKT1 Kits ELISA).

  10. data establish RASSF1A as a novel inhibitor of cardiac hypertrophy by modulating the extracellular regulated kinase 1/2 pathway.

Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) profil antigène

Antigen Summary

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with RASSF1

  • nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) anticorps
  • Ras association (RalGDS/AF-6) domain family 1 (rassf1) anticorps
  • Ras association (RalGDS/AF-6) domain family member 1 (RASSF1) anticorps
  • rassf1 (Smp_157340) anticorps
  • Ras association (RalGDS/AF-6) domain family member 1 (rassf1) anticorps
  • Ras association (RalGDS/AF-6) domain family member 1 (Rassf1) anticorps
  • 123F2 anticorps
  • AA536941 anticorps
  • AU044980 anticorps
  • NORE2A anticorps
  • RASSF1 anticorps
  • Rassf1A anticorps
  • Rassf1B anticorps
  • Rassf1C anticorps
  • RDA32 anticorps
  • REH3P21 anticorps
  • wu:fc17f02 anticorps
  • zgc:92505 anticorps
  • zgc:112224 anticorps

Protein level used designations for RASSF1

Ras association (RalGDS/AF-6) domain family 1 , Ras association (RalGDS/AF-6) domain family member 1 , ras association domain-containing protein 1 , Ras association domain family 1 , rassf1 , WUGSC:H_LUCA12.5 , cardiac-specific ras association domain family 1 protein , pancreas-specific ras association domain family 1 protein , tumor suppressor protein RDA32 , 123F protein , RASSF1A tumor suppressor , protein 123F2

GENE ID SPECIES
425132 Gallus gallus
447811 Danio rerio
702385 Macaca mulatta
744944 Pan troglodytes
8344706 Schistosoma mansoni
100036863 Xenopus laevis
100302080 Ovis aries
11186 Homo sapiens
56289 Mus musculus
363140 Rattus norvegicus
607929 Canis lupus familiaris
510276 Bos taurus
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