anti-Ribonuclease H2, Subunit B (RNASEH2B) Anticorps

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. De plus, nous expédions Ribonuclease H2, Subunit B Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RNASEH2B 79621 Q5TBB1
RNASEH2B 67153 Q80ZV0
RNASEH2B 361056 Q5XI96
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Top anti-Ribonuclease H2, Subunit B Anticorps sur anticorps-enligne.fr

Showing 10 out of 31 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of RNASEH2B Antibody (Center) (ABIN650970) in CEM cell line lysates (35 µg/lane). RNASEH2B (arrow) was detected using the purified polyclonal antibody. RNASEH2B Antibody (Center) (ABIN650970) IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué WB Western Blot: RNASEH2B Antibody (673) [NBP2-43776] - Analysis of Ferroportin in human fibroblasts using Ferroportin antibody. Image from verified customer review. Western Blot: RNASEH2B Antibody (673) [NBP2-43776] - Analysis of HeLa whole cell extracts and nuclear extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with RNaseH2B antibody at a dilution of 1:1000. 0.1 mL Connectez-vous pour afficher 4 to 7 Days
426,25 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: RNASEH2B Antibody [NBP1-90865] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human cell line MOLT-4 Immunocytochemistry/Immunofluorescence: RNASEH2B Antibody [NBP1-90865] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Humain Lapin Inconjugué ICC, IF Immunocytochemistry/Immunofluorescence: RNASEH2B Antibody  - Staining of human cell line A-431 shows localization to nucleoplasm. 100 μL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Humain Lapin Inconjugué ELISA, IHC, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
941,11 €
Détails
Humain Lapin PE IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
1.203,02 €
Détails
Humain Lapin FITC IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
1.203,02 €
Détails
Humain Lapin APC IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
1.203,02 €
Détails
Humain Lapin Biotin IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
1.203,02 €
Détails
Humain Lapin Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
1.203,02 €
Détails

RNASEH2B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,
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Mouse (Murine)


Rat (Rattus)


Plus d’anticorps contre Ribonuclease H2, Subunit B partenaires d’interaction

Human Ribonuclease H2, Subunit B (RNASEH2B) interaction partners

  1. This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2B in patients with Aicardi-Goutieres Syndrome.

  2. Aicardi-Goutieres syndrome 2 is caused by mutations in the ribonuclease H2 subunit B gene RNASEH2B.

  3. RNase H2 complex is assembled in the cytosol and imported into the nucleus in an RNase H2B-dependent manner.

  4. A genome-wide search for homozygosity in Aicardi-Goutieres syndrome patients in the Faroe Islands revealed one single 15.6 Mb region of homozygosity on chromosome 13, which included RNASEH2B, where a splice site mutation c.322-3C>G was identified.

  5. This study demonistrated that ribonuclease H2 mutation releated to Aicardi-Goutieres syndrome.

  6. Congenital infection is seen with preserved neurological function, most frequently due to RNASEH2B mutations.

  7. Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the B subunit of RNase H2.

Mouse (Murine) Ribonuclease H2, Subunit B (RNASEH2B) interaction partners

  1. Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

  2. Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review]

  3. Study performed targeted mutagenesis of the mouse Rnaseh2b gene to gain insight into the in vivo role of the mammalian RNase H2 enzyme. Ablation of Rnaseh2b in mice leads to early embryonic lethality due to elevated DNA damage and reduced cellular proliferation during gastrulation.

  4. Data show that the interwoven architecture of RNase H2B and RNase H2C (Montrer RNASEH2C Anticorps) that interface with RNase H2A (Montrer RNASEH2A Anticorps) in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs.

Ribonuclease H2, Subunit B (RNASEH2B) profil antigène

Profil protéine

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Gene names and symbols associated with RNASEH2B

  • ribonuclease H2, subunit B (RNASEH2B) anticorps
  • ribonuclease H2, subunit B (Rnaseh2b) anticorps
  • ribonuclease H2, subunit B (rnaseh2b) anticorps
  • 1110019N06Rik anticorps
  • 2610207P08Rik anticorps
  • AGS2 anticorps
  • Dleu8 anticorps

Protein level used designations for RNASEH2B

Aicardi-Goutieres syndrome 2 protein , RNase H2 subunit B , deleted in lymphocytic leukemia 8 , ribonuclease H2 subunit B , ribonuclease HI subunit B , deleted in lymphocytic leukemia 8 homolog

GENE ID SPECIES
79621 Homo sapiens
67153 Mus musculus
361056 Rattus norvegicus
509258 Bos taurus
496343 Xenopus laevis
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