anti-Ring Finger Protein 125 (RNF125) Anticorps

RNF125 encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. De plus, nous expédions RNF125 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RNF125 67664 Q9D9R0
RNF125 361296  
RNF125 54941 Q96EQ8
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Top anti-RNF125 Anticorps sur anticorps-enligne.fr

Showing 10 out of 51 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-RNF125 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: THP-1 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemical analysis of RNF125 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RNF125 expression in HEK293T (A), THP1 (B), 129Sv (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$221.76
Détails
Humain Souris Inconjugué ELISA, WB Detection limit for recombinant GST tagged RNF125 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: RNF125 Antibody [NBP1-83653] - Staining of human cell line A-431 shows positivity in nucleoli & golgi apparatus. Immunohistochemistry-Paraffin: RNF125 Antibody [NBP1-83653] - Staining of human pancreas shows moderate cytoplasmic and nuclear positivity in exocrine pancreas. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$439.69
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from K562/HT-29 cells, using RNF125 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Chien Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué IF, WB Immunofluorescence analysis of A549 cell using RNF125 antibody. Blue: DAPI for nuclear staining. Immunofluorescence analysis of A549 cell using RNF125 antibody. Blue: DAPI for nuclear staining. 100 μL Connectez-vous pour afficher 16 Days
$323.13
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB   50 μL Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails

RNF125 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Mouse (Murine) ,
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Rat (Rattus) ,
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anti-RNF125 Anticorps mieux référencés

  1. Human Polyclonal RNF125 Primary Antibody pour ICC, IF - ABIN4350731 : Kim, Frederick, Levesque, Cooper, Feng, Krepler, Brill, Samuels, Hayward, Perlina, Piris, Zhang, Halaban, Herlyn, Brown, Wargo, Dummer, Flaherty, Ronai: Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. dans Cell reports 2015 (PubMed)

Plus d’anticorps contre RNF125 partenaires d’interaction

Mouse (Murine) Ring Finger Protein 125 (RNF125) interaction partners

  1. study identifies new gene-type zinc finger protein 125 (RNF125) as a negative regulator of TRIM14 (Montrer TRIM14 Anticorps) in the innate antiviral immune response

  2. Data indicate that brain from Japanese encephalitis virus (JEV)-infection showed a (Montrer UTS2R Anticorps)reciprocal correlation between microRNA miR-15b levels and the ex (Montrer MLXIP Anticorps)pression of ring finger protein 125 (RNF125).

  3. RNF125 is enhanced by IFN, these functions constitute a negative regulatory loop circuit for IFN production

Human Ring Finger Protein 125 (RNF125) interaction partners

  1. study identifies new gene-type zinc finger protein 125 (RNF125) as a negative regulator of TRIM14 (Montrer TRIM14 Anticorps) in the innate antiviral immune response

  2. we identified the downregulation of the ubiquitin ligase RNF125 in BRAFi-resistant melanomas

  3. Results indicate that the nucleotide sequence in the 3' untranslated region (3' UTR (Montrer UTS2R Anticorps)) of ring finger protein 125 (RNF125) is a potential microRNA miR (Montrer MLXIP Anticorps)-15b targeting site.

  4. studies of the RNF125 pathway point to upregulation of RIG-I (Montrer DDX58 Anticorps)-IPS1 (Montrer MAVS Anticorps)-MDA5 (Montrer IFIH1 Anticorps) and/or disruption of the PI3K (Montrer PIK3CA Anticorps)-AKT (Montrer AKT1 Anticorps) and interferon (Montrer IFNA Anticorps) signaling pathways as the putative final effectors

  5. In controls, RNF125 is the highest expressed gene, whereas in HIV infection progressors, RIG-I (Montrer DDX58 Anticorps) is either the highest expressed gene or is expressed similarly to RNF125 and TRIM25 (Montrer TRIM25 Anticorps).

  6. study reports human bocavirus VP2 modulates IFN pathway by targeting the ring finger protein 125, a negative regulator of type I IFN signaling, which conjugates Lys (Montrer LYZ Anticorps)(48)-linked ubiquitination to retinoic acid-inducible gene-I (Montrer DDX58 Anticorps) and leads to the proteasome-dependent degradation of RIG-I (Montrer DDX58 Anticorps)

  7. These results suggest that RNF125/TRAC-1 could function to recruit host factor(s) controlling HIV-1 transcription to the ubiquitin-proteasome pathway.

  8. TRAC-1 associates with membranes and is excluded from the nucleus through myristoylation

RNF125 profil antigène

Profil protéine

This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.

Gene names and symbols associated with RNF125

  • ring finger protein 125 (RNF125) anticorps
  • ring finger protein 125 (Rnf125) anticorps
  • ring finger protein 125, E3 ubiquitin protein ligase (RNF125) anticorps
  • 4930553F04Rik anticorps
  • TRAC-1 anticorps
  • TRAC1 anticorps

Protein level used designations for RNF125

E3 ubiquitin-protein ligase RNF125 , T-cell RING activation protein 1 , T-cell ring protein identified in activation screen

GENE ID SPECIES
519541 Bos taurus
67664 Mus musculus
361296 Rattus norvegicus
54941 Homo sapiens
743809 Pan troglodytes
490498 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour anti-RNF125 (RNF125) Anticorps
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