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Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. De plus, nous expédions RNF2 Protéines (7) et RNF2 Kits (1) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 64 products:
Human Monoclonal RNF2 Primary Antibody pour ChIPSeq, ChIP - ABIN2668629
Basu, Wilkinson, Colavita, Fennelly, Atchison: YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. dans Nucleic acids research 2014
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Human Monoclonal RNF2 Primary Antibody pour RNAi, ELISA - ABIN562662
Ohtsubo, Yasunaga, Ohno, Tsumura, Okada, Ishikawa, Shirao, Kikuchi, Nishitani, Kobayashi, Takihara: Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. dans Proceedings of the National Academy of Sciences of the United States of America 2008
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Human Polyclonal RNF2 Primary Antibody pour IHC, IHC (p) - ABIN4350772
Holdt, Hoffmann, Sass, Langenberger, Scholz, Krohn, Finstermeier, Stahringer, Wilfert, Beutner, Gielen, Schuler, Gäbel, Bergert, Bechmann, Stadler, Thiery, Teupser: Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. dans PLoS genetics 2013
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Human Polyclonal RNF2 Primary Antibody pour ELISA, WB - ABIN268569
Tuckfield, Clouston, Wilanowski, Zhao, Cunningham, Jane: Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. dans Molecular and cellular biology 2002
The polycomb group protein (Montrer CBX4 Anticorps) ring1b/rnf2 is specifically required for craniofacial development.
These results reveal that, in the absence of functional Ring1b, fin bud cells fail to execute the pectoral fin developmental program.
Study detected RNF2 expression to be overexpressed in esophageal carcinoma cell lines and was associated with the poor prognosis of esophageal carcinoma patients. Data also reflect its important role in the growth of esophageal carcinoma cells by shRNA silencing of RNF2 expression.
overexpression of RNF2, as examined by immunohistochemical analysis, might serve as a novel prognostic biomarker and potential therapeutic target for urothelial carcinoma of the bladder patients.
Our findings support the notion that epigenetic regulators, such as RNF2, directly and functionally control powerful gene networks that are vital in multiple cancer processes.
O-GlcNAc (Montrer OGT Anticorps) modifies and regulates an essential epigenetic tool, RING1B, which may contribute to human embryonic stem cells pluripotency maintenance and differentiation.
The enzymatic activity of BMI1 (Montrer BMI1 Anticorps) and RING1B were evaluated and compared.
Bmi1 (Montrer BMI1 Anticorps) and possibly RNF2 may be attractive biomarkers of gemcitabine resistance in the context of RRM1 (Montrer RRM1 Anticorps) expression.
combinatorial silencing along with Ezh2 (Montrer EZH2 Anticorps) depleted epigenetically modified H2- and H3-histones and inhibited pancreatic cancer cell growth in vitro and in vivo (xenograft model)
BAP1 deficiency causes increased expression of FoxK2 (Montrer FOXK2 Anticorps) target genes in a Ring1B-Bmi1 (Montrer BMI1 Anticorps)-dependent manner
Authors describe a critical role for the polycomb group protein Ring1b in nonhomologous end-joining (NHEJ)-mediated end-to-end chromosome fusions.
we identify p63 (Montrer RPE65 Anticorps) as a target of Ring1B to regulate Fak (Montrer PTK2 Anticorps) expression in breast cancer epithelial cells
the ability of RING1B, a core component of PRC1 (Montrer PRC1 Anticorps), to ubiquitinate histone H2A is dispensable for early mouse embryonic development and much of the gene repression activity of PRC1 (Montrer PRC1 Anticorps)
RNF2 associates with AMBRA1 (Montrer AMBRA1 Anticorps) to act as an E3 ligase to ubiquitinate AMBRA1 (Montrer AMBRA1 Anticorps) via K48 linkage.
The polycomb (Montrer CBX2 Anticorps) component Ring1B regulates the timed termination of Fezf2 (Montrer FEZF2 Anticorps) expression and thus subcerebral projection neuron production during mouse neocortical development.
Expansion of hepatic stem/progenitor cells requires Ring1B-mediated epigenetic silencing of Cdkn1a (Montrer CDKN1A Anticorps) and Cdkn2a (Montrer CDKN2A Anticorps), demonstrating that Ring1B simultaneously regulates multiple CDKIs in tissue stem/progenitor cells.
Af9 (Montrer MLLT3 Anticorps) mediates site-selective physical and functional recruitment of Rnf2 to the alpha-ENaC (Montrer SCNN1A Anticorps) promoter to constrain basal alpha-ENaC (Montrer SCNN1A Anticorps) transcription in collecting duct cells.
Ring1b mediates Meis2 (Montrer MEIS2 Anticorps) promoter and midbrain-specific enhancer association.
Aurora B (Montrer AURKC Anticorps) and Ring1B co-occupy active promoters in resting lymphocytes.
Fbxl10 (Montrer KDM2B Anticorps) has a key role in regulating Ring1B recruitment to its target genes and H2AK119 ubiquitylation in embryonic stem cells.
identification of gene-dosage-dependent roles in primordial germ cell development for Ring1 (Montrer RING1 Anticorps) and Rnf2, two central components of the Polycomb (Montrer CBX2 Anticorps) repressive complex 1 (PRC1 (Montrer PRC1 Anticorps))
Ring1b inactivation in differentiated islet beta cells (Ring1b(betaKO)) did not cause derepression, even after multiple rounds of cell division, suggesting a role for Ring1b in the establishment but not the maintenance of repression
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
E3 ubiquitin-protein ligase RING2
, ring finger protein 1b
, RING finger protein 1B
, HIP2-interacting protein 3
, RING finger protein BAP-1
, huntingtin-interacting protein 2-interacting protein 3
, protein DinG