anti-Ring Finger Protein 2 (RNF2) Anticorps

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. De plus, nous expédions RNF2 Protéines (7) et RNF2 Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RNF2 6045 Q99496
RNF2 19821 Q9CQJ4
RNF2 304850 Q4KLY4
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Top anti-RNF2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 64 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-RNF2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Daudi cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-RNF2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Souris Inconjugué WB Western Blot analysis of RNF2 expression in transfected 293T cell line by RNF2 monoclonal antibody (M01), clone 6C2. Lane 1: RNF2 transfected lysate(37.7 KDa). Lane 2: Non-transfected lysate. Western blot analysis of RNF2 over-expressed 293 cell line, cotransfected with RNF2 Validated Chimera RNAi used as specificity and loading control. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Hamster Souris Inconjugué IP, WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$456.50
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN184925 staining (0.5 µg/ml) of K562 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$326.89
Détails
Humain Souris Inconjugué WB RNF2 monoclonal antibody (M14), clone 2B4. Western Blot analysis of RNF2 expression in A-549. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of RING2/RING1B/RNF2 expression in rat brain extract (lane 1), and HELA whole cell lysates (lane 2). RING2/RING1B/RNF2 at 38KD was detected using rabbit anti- RING2/RING1B/RNF2 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method RING2/RING1B/RNF2 was detected in paraffin-embedded sections of human mammary cancer tissues using rabbit anti- RING2/RING1B/RNF2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Connectez-vous pour afficher 4 to 6 Days
$200.00
Détails
Poulet Chèvre Inconjugué EIA, IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$419.10
Détails
Humain Lapin Inconjugué IHC, IHC (p), IP, WB Western Blot: RNF2 Antibody [NBP1-49966] - Detection of Human and Mouse RNF2 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from K562 (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-RNF2 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. RNF2 was also immunoprecipitated by rabbit anti-RNF2 antibody, which recognizes a downstream epitope. For blotting immunoprecipitated RNF2 was used. Detection: Chemiluminescence with exposure times of 30 seconds (A and B). Immunohistochemistry-Paraffin: RNF2 Antibody [NBP1-49966] - Human prostate carcinoma. Antibody used at a dilution of 1:1,000. 100 μL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Souris Inconjugué ChIPSeq, ChIP, ICC, IF, IP, WB Ring1B antibody (mAb) tested by ChIP-chip. ChIP was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with chromatin from 4.5 million human embryonic stem cells and 4 µl of antibody. ChIP DNA was amplified by WGA, labeled and hybridized to a human tiling array. The two images show regions of strong binding on chromosomes 2 and 9. 100 μg Connectez-vous pour afficher 1 to 2 Days
$507.50
Détails

RNF2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine)
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Rat (Rattus)
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anti-RNF2 Anticorps mieux référencés

  1. Human Monoclonal RNF2 Primary Antibody pour ChIPSeq, ChIP - ABIN2668629 : Basu, Wilkinson, Colavita, Fennelly, Atchison: YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. dans Nucleic acids research 2014 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF2 Primary Antibody pour RNAi, ELISA - ABIN562662 : Ohtsubo, Yasunaga, Ohno, Tsumura, Okada, Ishikawa, Shirao, Kikuchi, Nishitani, Kobayashi, Takihara: Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal RNF2 Primary Antibody pour IHC, IHC (p) - ABIN4350772 : Holdt, Hoffmann, Sass, Langenberger, Scholz, Krohn, Finstermeier, Stahringer, Wilfert, Beutner, Gielen, Schuler, Gäbel, Bergert, Bechmann, Stadler, Thiery, Teupser: Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. dans PLoS genetics 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal RNF2 Primary Antibody pour ELISA, WB - ABIN268569 : Tuckfield, Clouston, Wilanowski, Zhao, Cunningham, Jane: Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. dans Molecular and cellular biology 2002 (PubMed)

Plus d’anticorps contre RNF2 partenaires d’interaction

Zebrafish Ring Finger Protein 2 (RNF2) interaction partners

  1. The polycomb group protein (Montrer CBX4 Anticorps) ring1b/rnf2 is specifically required for craniofacial development.

  2. These results reveal that, in the absence of functional Ring1b, fin bud cells fail to execute the pectoral fin developmental program.

Human Ring Finger Protein 2 (RNF2) interaction partners

  1. Study detected RNF2 expression to be overexpressed in esophageal carcinoma cell lines and was associated with the poor prognosis of esophageal carcinoma patients. Data also reflect its important role in the growth of esophageal carcinoma cells by shRNA silencing of RNF2 expression.

  2. overexpression of RNF2, as examined by immunohistochemical analysis, might serve as a novel prognostic biomarker and potential therapeutic target for urothelial carcinoma of the bladder patients.

  3. Our findings support the notion that epigenetic regulators, such as RNF2, directly and functionally control powerful gene networks that are vital in multiple cancer processes.

  4. O-GlcNAc (Montrer OGT Anticorps) modifies and regulates an essential epigenetic tool, RING1B, which may contribute to human embryonic stem cells pluripotency maintenance and differentiation.

  5. The enzymatic activity of BMI1 (Montrer BMI1 Anticorps) and RING1B were evaluated and compared.

  6. Bmi1 (Montrer BMI1 Anticorps) and possibly RNF2 may be attractive biomarkers of gemcitabine resistance in the context of RRM1 (Montrer RRM1 Anticorps) expression.

  7. combinatorial silencing along with Ezh2 (Montrer EZH2 Anticorps) depleted epigenetically modified H2- and H3-histones and inhibited pancreatic cancer cell growth in vitro and in vivo (xenograft model)

  8. BAP1 deficiency causes increased expression of FoxK2 (Montrer FOXK2 Anticorps) target genes in a Ring1B-Bmi1 (Montrer BMI1 Anticorps)-dependent manner

  9. Authors describe a critical role for the polycomb group protein Ring1b in nonhomologous end-joining (NHEJ)-mediated end-to-end chromosome fusions.

  10. we identify p63 (Montrer RPE65 Anticorps) as a target of Ring1B to regulate Fak (Montrer PTK2 Anticorps) expression in breast cancer epithelial cells

Mouse (Murine) Ring Finger Protein 2 (RNF2) interaction partners

  1. the ability of RING1B, a core component of PRC1 (Montrer PRC1 Anticorps), to ubiquitinate histone H2A is dispensable for early mouse embryonic development and much of the gene repression activity of PRC1 (Montrer PRC1 Anticorps)

  2. RNF2 associates with AMBRA1 (Montrer AMBRA1 Anticorps) to act as an E3 ligase to ubiquitinate AMBRA1 (Montrer AMBRA1 Anticorps) via K48 linkage.

  3. The polycomb (Montrer CBX2 Anticorps) component Ring1B regulates the timed termination of Fezf2 (Montrer FEZF2 Anticorps) expression and thus subcerebral projection neuron production during mouse neocortical development.

  4. Expansion of hepatic stem/progenitor cells requires Ring1B-mediated epigenetic silencing of Cdkn1a (Montrer CDKN1A Anticorps) and Cdkn2a (Montrer CDKN2A Anticorps), demonstrating that Ring1B simultaneously regulates multiple CDKIs in tissue stem/progenitor cells.

  5. Af9 (Montrer MLLT3 Anticorps) mediates site-selective physical and functional recruitment of Rnf2 to the alpha-ENaC (Montrer SCNN1A Anticorps) promoter to constrain basal alpha-ENaC (Montrer SCNN1A Anticorps) transcription in collecting duct cells.

  6. Ring1b mediates Meis2 (Montrer MEIS2 Anticorps) promoter and midbrain-specific enhancer association.

  7. Aurora B (Montrer AURKC Anticorps) and Ring1B co-occupy active promoters in resting lymphocytes.

  8. Fbxl10 (Montrer KDM2B Anticorps) has a key role in regulating Ring1B recruitment to its target genes and H2AK119 ubiquitylation in embryonic stem cells.

  9. identification of gene-dosage-dependent roles in primordial germ cell development for Ring1 (Montrer RING1 Anticorps) and Rnf2, two central components of the Polycomb (Montrer CBX2 Anticorps) repressive complex 1 (PRC1 (Montrer PRC1 Anticorps))

  10. Ring1b inactivation in differentiated islet beta cells (Ring1b(betaKO)) did not cause derepression, even after multiple rounds of cell division, suggesting a role for Ring1b in the establishment but not the maintenance of repression

RNF2 profil antigène

Profil protéine

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Gene names and symbols associated with RNF2

  • ring finger protein 2 (rnf2) anticorps
  • ring finger protein 2 (RNF2) anticorps
  • ring finger protein 2 (Rnf2) anticorps
  • AI326319 anticorps
  • AI450156 anticorps
  • AU019207 anticorps
  • bap-1 anticorps
  • bap1 anticorps
  • ding anticorps
  • fa19h05 anticorps
  • hipi3 anticorps
  • Ring1B anticorps
  • ring2 anticorps
  • wu:fa19h05 anticorps
  • wz4556 anticorps

Protein level used designations for RNF2

E3 ubiquitin-protein ligase RING2 , ring finger protein 1b , wz4566 , RING finger protein 1B , HIP2-interacting protein 3 , RING finger protein BAP-1 , huntingtin-interacting protein 2-interacting protein 3 , protein DinG , RING1b

GENE ID SPECIES
327035 Danio rerio
424452 Gallus gallus
457581 Pan troglodytes
100174504 Pongo abelii
6045 Homo sapiens
480042 Canis lupus familiaris
540090 Bos taurus
19821 Mus musculus
304850 Rattus norvegicus
100127274 Xenopus laevis
Fournisseurs de qualité sélectionnés pour anti-RNF2 (RNF2) Anticorps
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