anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) Anticorps

The protein encoded by SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. De plus, nous expédions SMAD5 Protéines (14) et SMAD5 Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SMAD5 4090 Q99717
SMAD5 17129 P97454
SMAD5 59328 Q9R1V3
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Top anti-SMAD5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 108 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-SMAD5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-SMAD5  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué WB SMAD5 Antibody (Center) (ABIN1881816) pre-incubated without(lane 1) and with(lane 2) blocking peptide in Hela cell line lysate. SMAD5 Antibody (Center) (arrow) was detected using the purified Pab. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué ICC, FACS, IHC, ELISA, WB Figure 1: Flow cytometric analysis of Jurkat cells using SMAD5 mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of NTERA-2 cells using SMAD5 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. 100 μL Connectez-vous pour afficher 6 to 8 Days
453,56 €
Détails
Humain Lapin Inconjugué IHC (p), WB Anti-SMAD5 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-SMAD5 antibody, IHC(P) IHC(P): Rat Intestine Tissue 100 μg Connectez-vous pour afficher 8 to 11 Days
298,57 €
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Uterus, antibody was diluted at 1:100. 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué ICC, IF, WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using SMAD5, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2000. 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of SMAD5 expression in HeLa (A), mouse testis (B), PC12 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 11 to 13 Days
464,29 €
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IF, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
618,10 €
Détails
Humain Souris Inconjugué FACS, ICC, WB   100 μL Connectez-vous pour afficher 10 to 13 Days
190,48 €
Détails

SMAD5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-SMAD5 Anticorps mieux référencés

  1. Human Polyclonal SMAD5 Primary Antibody pour WB - ABIN1881816 : Park, Lee, Ahn, Kim: Predicting the multi-modal binding propensity of small molecules: towards an understanding of drug promiscuity. dans Molecular bioSystems 2009 (PubMed)
    Show all 5 references for 1881816

  2. Human Monoclonal SMAD5 Primary Antibody pour ICC, FACS - ABIN969404 : Chang, Chang, Lee, Lee, Yeh, Yeh, Cheng, Chien, Chiu: Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 2 references for 969404

  3. Cow (Bovine) Polyclonal SMAD5 Primary Antibody pour WB - ABIN2779414 : Zimonjic, Durkin, Keck-Waggoner, Park, Thorgeirsson, Popescu: SMAD5 gene expression, rearrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinoma. dans Neoplasia (New York, N.Y.) 2003 (PubMed)

Plus d’anticorps contre SMAD5 partenaires d’interaction

Zebrafish SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. TGFbeta1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway.

  2. Alk3 and Alk3b, as well as SMAD5, are essential cellular mediators of BMP signaling in zebrfish.

  3. Data show that interplay of Smad1 (Montrer SMAD1 Anticorps)/5 and MAP kinase (Montrer MAPK1 Anticorps) signaling system (ERK (Montrer MAPK1 Anticorps) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  4. this study uncovers that smad1 (Montrer SMAD1 Anticorps) and smad9 (Montrer SMAD9 Anticorps) act redundantly to each other downstream of smad5 to mediate ventral specification and to regulate embryonic myelopoiesis.

  5. Functional investigation of a subset of these genes, fgf10a (Montrer FGF10 Anticorps), tgfb2 (Montrer TGFB2 Anticorps), pax9 (Montrer PAX9 Anticorps), and smad5 revealed their necessity in zebrafish palatogenesis.

  6. maternally supplied Smad5 is already required to mediate ventral specification prior to zygotic Bmp2 (Montrer BMP4 Anticorps)/7 signaling to establish the initial dorsoventral asymmetry

  7. Data show that patterning of the eye primordia in Smad5-deficient embryos starts during blastula and early gastrula stages.

  8. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 (Montrer SMAD1 Anticorps) and Smad5.

  9. Data show that Smad5 expression is ubiquitous during testis development but becomes cell-specific in the adult.

Human SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. the BMP-2 (Montrer BMP2 Anticorps)/Smad1 (Montrer GARS Anticorps)/5/RUNX2 (Montrer RUNX2 Anticorps) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin (Montrer BGLAP Anticorps) synth

  2. miR (Montrer MLXIP Anticorps)-23a and miR (Montrer MLXIP Anticorps)-27a target SMAD5 and regulate apoptosis in human granulosa cells via the FasL (Montrer FASL Anticorps)-Fas (Montrer FAS Anticorps) pathway

  3. Our findings suggest that suppression of miR (Montrer MLXIP Anticorps)-222-3p activity promoted osteogenic differentiation hBMSCs through regulating Smad5-RUNX2 (Montrer RUNX2 Anticorps) signaling axis.

  4. Overexpression of the BMP4 (Montrer BMP4 Anticorps)/SMAD4 (Montrer SMAD4 Anticorps)/SMAD5 signaling pathway could predict poor clinical outcome in skull base chordomas, suggesting activation of this pathway is involved in chordoma pathogenesis.

  5. The polycomb group protein L3MBTL1 (Montrer L3MBTL1 Anticorps) represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.

  6. adult human Sertoli cells assumed similar morphological features, stable global gene expression profiles and numerous proteins, and activation of AKT (Montrer AKT1 Anticorps) and SMAD1 (Montrer GARS Anticorps)/5 during long-period culture.

  7. balance between Smad1 (Montrer GARS Anticorps)/5- and Smad2 (Montrer SMAD2 Anticorps)/3-dependent signaling defines the outcome of the effect of TGF-beta (Montrer TGFB1 Anticorps) on atherosclerosis where Smad1 (Montrer GARS Anticorps)/5 is responsible for proatherogenic effects

  8. among the 15 SNPs, rs3206634 was significantly associated with KD in a recessive model (odds ratio = 2.31, p = 0.019), whereas there was no association between any of the 15 SNPs and CALs (Montrer CA8 Anticorps).

  9. Our results indicated that KGN promoted the type-I collagen synthesis of dermal fibroblasts in vitro and in the dermis of mice through activation of the smad4 (Montrer SMAD4 Anticorps)/smad5 pathway.

  10. Inhibiting Smurf1 (Montrer SMURF1 Anticorps) mediated ubiquitination of Smad1 (Montrer GARS Anticorps)/5.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. these studies characterize an accessory TGF-beta (Montrer TGFB1 Anticorps)-stimulated BMP R-Smad (Montrer SMAD1 Anticorps) signaling mechanism in interstitial cells of the developing lung.

  2. Thyroid-specific Smad1 (Montrer SMAD1 Anticorps) and Smad5 double-knockout (Smad1 (Montrer SMAD1 Anticorps)/5(dKO)) mice displayed growth retardation, hypothyroidism and defective follicular architecture.

  3. Smad1 (Montrer SMAD1 Anticorps) and Smad5 have overlapping functions to govern hepcidin (Montrer HAMP Anticorps) transcription. Moreover, erythropoietin (Montrer EPO Anticorps) and erythroferrone target Smad1 (Montrer SMAD1 Anticorps)/5 signaling and require Smad1 (Montrer SMAD1 Anticorps)/5 to suppress hepcidin (Montrer HAMP Anticorps) expression.

  4. miR (Montrer MLXIP Anticorps)-106b-5p and miR-17-5p are novel Smad5 regulators.

  5. BetA can enhance in vivo osteogenic potentials of BMP2 (Montrer BMP2 Anticorps), possibly via stimulating Smad 1 (Montrer SMAD1 Anticorps)/5/8 and p38 (Montrer CRK Anticorps) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.

  6. Data show that in R-Smad (Montrer SMAD1 Anticorps) proteins Smad1 (Montrer SMAD1 Anticorps);Smad5 knockout embryonic stem cells (mESCs), the bone morphogenetic proteins (BMP)-SMAD (Montrer SMAD1 Anticorps) signaling is dispensable for self-renewal.

  7. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  8. The crystal structure of Smad5-MH1 (Montrer SCN5A Anticorps) domain in complex with a composite DNA sequence demonstrates that the MH1 (Montrer SCN5A Anticorps) domain is targeted to a binding site with modular binding modes, and the length of the DNA spacer affects the MH1 (Montrer SCN5A Anticorps) assembly.

  9. The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (Montrer BMP2 Anticorps)/Smad1 (Montrer SMAD1 Anticorps)/5/8 and Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathways.

  10. FLI1 (Montrer FLI1 Anticorps) and GATA2 (Montrer GATA2 Anticorps) are upstream regulators of SMAD1 (Montrer SMAD1 Anticorps) and SMAD5 expression in endothelial cells.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. a detailed computational model for TGF-beta (Montrer TGFB1 Anticorps) signalling that incorporates elements of previous models together with crosstalking between Smad1 (Montrer SMAD1 Anticorps)/5/8 and Smad2 (Montrer SMAD2 Anticorps)/3 channels through a negative feedback loop dependent on Smad7 (Montrer SMAD7 Anticorps).

SMAD5 profil antigène

Profil protéine

The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with SMAD5

  • SMAD family member 5 (SMAD5) anticorps
  • MAD homolog 5 (Drosophila) (smad5) anticorps
  • SMAD family member 4, gene 2 (smad4.2-b) anticorps
  • SMAD family member 5 (Smad5) anticorps
  • 1110051M15Rik anticorps
  • AI451355 anticorps
  • DKFZp468M0619 anticorps
  • dpc4 anticorps
  • Dwf-C anticorps
  • DWFC anticorps
  • fb67b04 anticorps
  • jip anticorps
  • JV5-1 anticorps
  • mad anticorps
  • madh4 anticorps
  • Madh5 anticorps
  • MusMLP anticorps
  • sb:cb400 anticorps
  • SBN anticorps
  • SMAD5 anticorps
  • smad10 anticorps
  • smd5 anticorps
  • wu:fb67b04 anticorps
  • xsmad4 anticorps
  • XSmad4alpha anticorps

Protein level used designations for SMAD5

mothers against decapentaplegic homolog 5 , SMA- and MAD-related protein 5 , SMAD 5 , SMAD family member 5 , mothers against DPP homolog 5 , pgy , piggytail , somitabun , MAD, mothers against decapentaplegic homolog 5 , SMAD, mothers against DPP homolog 5 , mothers against decapentaplegic, drosophila, homolog of, 5 , MAD homolog 5 , Smad 5 , dwarfin-C , mSmad5 , Mothers against decapentaplegic homolog 5

GENE ID SPECIES
100033851 Equus caballus
30641 Danio rerio
403398 Xenopus laevis
4090 Homo sapiens
17129 Mus musculus
59328 Rattus norvegicus
395679 Gallus gallus
481520 Canis lupus familiaris
768050 Bos taurus
100173534 Pongo abelii
100303615 Sus scrofa
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