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Sclerostin (SOST) Kits ELISA

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. De plus, nous expédions Sclerostin Anticorps (98) et Sclerostin Protéines (18) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SOST 50964 Q9BQB4
SOST 74499 Q99P68
SOST 80722 Q99P67
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Top Sclerostin Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 49 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 7 to 10 Days
874,71 €
Détails
Souris 10pg/mL 15.6-1000 pg/mL Mouse Sclerostin/SOST PicoKine ELISA Kit standard curve 96 Tests Connectez-vous pour afficher 8 to 11 Days
507,05 €
Détails
Rat 32 pg/mL 78-5.000 pg/mL 96 Tests Connectez-vous pour afficher 7 to 10 Days
804,23 €
Détails
Boeuf (Vache) 15.63 pg/mL 4000-62.5 pg/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
874,71 €
Détails
Cobaye 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Lapin 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Singe 0.1 ng/mL 1.0-25 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Chien 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Porc
  96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Mouton
  96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails

Sclerostin Kits ELISA mieux référencés

  1. Human Sclerostin Kit ELISA pour Sandwich ELISA - ABIN457071 : Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. dans Gynecologic and obstetric investigation 2013 (PubMed)
    Show all 5 references for ABIN457071

  2. Rat (Rattus) Sclerostin Kit ELISA pour Sandwich ELISA - ABIN416496 : Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. dans Life sciences 2013 (PubMed)
    Show all 2 references for ABIN416496

  3. Mouse (Murine) Sclerostin Kit ELISA pour Sandwich ELISA - ABIN1889353 : Brunkow, Gardner, Van Ness, Paeper, Kovacevich, Proll, Skonier, Zhao, Sabo, Fu, Alisch, Gillett, Colbert, Tacconi, Galas, Hamersma, Beighton, Mulligan: Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. dans American journal of human genetics 2001 (PubMed)
    Show all 2 references for ABIN1889353

Plus Kits ELISA pour Sclerostin partenaires d'interaction

Human Sclerostin (SOST) interaction partners

  1. Sclerostin is an osteocyte marker that is strongly expressed in human woven and lamellar bone and mineralizing chondrocytes

  2. similar levels in type 1 diabetes patients and controls; decrease concurrent with adolescent growth spurt (Montrer BPIFA1 Kits ELISA)

  3. Findings indicate that sclerostin expression is closely associated with the degree of joint damage in primary knee osteoarthritis (OA), confirming its involvement in the development of OA.

  4. Results suggest that sclerostin may have a role in the development of or the response to abdominal aortic calcification in chronic kidney disease.

  5. while showing that exercise against bone loss in experimental bed rest results in greater bone formation, could not provide evidence that exercise impeded the rise in serum sclerostin and dickkopf-1 (Montrer DKK1 Kits ELISA) levels.

  6. serum sclerostin levels were lower in nonalcoholic steatohepatitis patients than in controls.

  7. The aim of this study was to evaluate the renal handling of sclerostin.

  8. Circulating sclerostin and dickkopf-1 (Montrer DKK1 Kits ELISA) levels in ossification of the posterior longitudinal ligament of the spine.

  9. chronic TNFalpha (tumor necrosis factor alpha (Montrer TNF Kits ELISA))-dependent arthritis, fibroblast-like synoviocytes constitute a major source of sclerostin and that either the lack of sclerostin or its antibody-mediated inhibition leads to an acceleration of rheumatoid arthritis (RA)-like disease.

  10. Sclerostin levels are elevated in CKD patients and are associated with inflammation, vascular lesions, uremia and (potentially) mortality.

Mouse (Murine) Sclerostin (SOST) interaction partners

  1. removal of sclerostin appears to modestly protect the alveolar bone from resorption in this experimental setting

  2. chronic TNFalpha (tumor necrosis factor alpha (Montrer TNF Kits ELISA))-dependent arthritis, fibroblast-like synoviocytes constitute a major source of sclerostin and that either the lack of sclerostin or its antibody-mediated inhibition leads to an acceleration of rheumatoid arthritis (RA)-like disease.

  3. Data show that the phenotype of Notch (Montrer NOTCH1 Kits ELISA) activation in osteocytes was prevented in matrix protein 1 (Dmp1 (Montrer DMP1 Kits ELISA))-Cre;Rosa(Notch (Montrer NOTCH1 Kits ELISA)) mice hemizygous for the Dmp1 (Montrer DMP1 Kits ELISA)-sclerostin (SOST) transgene.

  4. Results found that sclerostin enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (Montrer TAZ Kits ELISA)-responsive transcriptional activity and TAZ (Montrer TAZ Kits ELISA)-responsive gene expression, indicating a role for TAZ (Montrer TAZ Kits ELISA) as a regulator of adipogenesis by sclerostin.

  5. Our results suggested that sclerostin could be expressed in the liver and sustained successfully at high levels in the blood by using the PhiC31 integrase system, leading to trabecular bone loss.

  6. Sclerostin depletion enhances tibial fracture healing.

  7. SOST gene is involved in the regulation of renal interstitial fibrosis (RIF) progression. In obstructive kidney injury, SOST gene deletion would probably enhance renal fibrogenic response and promote the progression of RIF.

  8. Data (including data from studies in knockout/transgenic mice) suggest that Lrp6 (lipoprotein receptor-related protein 6 (Montrer LRP6 Kits ELISA)) is required for suppression of Sost expression by parathyroid hormone (Montrer PTH Kits ELISA) (here, human PTH (Montrer PTH Kits ELISA) peptide 1-34).

  9. These in vivo data support in vitro studies regarding the mechanism of HBM (Montrer LRP5 Kits ELISA)-causing mutations, and imply that HBM LRP5 (Montrer LRP5 Kits ELISA) receptors differ in their relative sensitivity to inhibition by SOST and DKK1 (Montrer DKK1 Kits ELISA).

  10. These findings indicated that AMPK (Montrer PRKAA1 Kits ELISA) regulated RANKL (Montrer TNFSF11 Kits ELISA) and sclerostin expression through the mevalonate pathway in osteocytes.

Sclerostin (SOST) profil antigène

Antigen Summary

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Gene names and symbols associated with Sclerostin (SOST) Kits ELISA

  • sclerostin (LOC100313724) anticorps
  • sclerostin (SOST) anticorps
  • sclerostin (Sost) anticorps
  • sclerostin-like (LOC100513306) anticorps
  • 5430411E23Rik anticorps
  • CDD anticorps
  • LOC100313724 anticorps
  • VBCH anticorps

Protein level used designations for Sclerostin (SOST) Kits ELISA

sclerostin , sclerosteosis

GENE ID SPECIES
100313724 Saccoglossus kowalevskii
50964 Homo sapiens
74499 Mus musculus
80722 Rattus norvegicus
490948 Canis lupus familiaris
100730713 Cavia porcellus
282880 Bos taurus
429784 Gallus gallus
101114123 Ovis aries
100513306 Sus scrofa
Fournisseurs de qualité sélectionnés pour Sclerostin (SOST) Kits ELISA
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