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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) Anticorps

TIMP1 belongs to the TIMP gene family. De plus, nous expédions TIMP1 Protéines (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TIMP1 7076 P01033
Anti-Rat TIMP1 TIMP1 116510 P30120
Anti-Souris TIMP1 TIMP1 21857 P12032
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Catalogue No. Reactivité Hôte Conjugué Application Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 4 to 5 Days
209,00 €
Détails

TIMP1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human ,

anti-TIMP1 Anticorps mieux référencés

  1. Human Monoclonal TIMP1 Primary Antibody pour ELISA, WB - ABIN108398 : Clark, Powell, Wright, Cawston: Polyclonal and monoclonal antibodies against human tissue inhibitor of metalloproteinases (TIMP) and the design of an enzyme-linked immunosorbent assay to measure TIMP. dans Matrix (Stuttgart, Germany) 1991 (PubMed)

Plus d’anticorps contre TIMP1 partenaires d’interaction

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Data show that serum neuron-specific enolase (Montrer ENO2 Anticorps), cytokeratin 19 (Montrer KRT19 Anticorps) fragment 21-1, pro-gastrin-releasing peptide (Montrer GRP Anticorps), squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.

  2. association of the TIMP-1 gene with recurrent aphthous stomatitis was ruled out based on our results.

  3. increased levels in saliva (Montrer RAG1AP1 Anticorps) and serum in women with polycystic ovary syndrome, and is

  4. TIMP-1 and MMP-9 (Montrer MMP9 Anticorps)/TIMP-1 ratio, but not MMP-9 (Montrer MMP9 Anticorps), were good diagnostic biomarkers of sepsis-associated acute kidney injury

  5. TIMP1, TIMP2 (Montrer TIMP2 Anticorps), and TIMP4 (Montrer TIMP4 Anticorps) are increased in aqueous humor from primary open angle glaucoma patients.

  6. determined normal concentration ranges for MMP-1 (Montrer MMP1 Anticorps), MMP-2 (Montrer MMP2 Anticorps), MMP-9 (Montrer MMP9 Anticorps), TIMP-1, and ratios of concentrations of MMPs and TIMP-1 (MMP-1 (Montrer MMP1 Anticorps)/TIMP-1, MMP-2 (Montrer MMP2 Anticorps)/TIMP-1, MMP-9 (Montrer MMP9 Anticorps)/TIMP-1) in the amniotic fluid at the first period of labor in physiological pregnancy.

  7. TIMP1 is elevated in patients with non-alcoholic fatty liver disease.

  8. TIMP-1 dependent inhibition of apoptosis occurs through p90RSK (Montrer RPS6KA1 Anticorps), with phosphorylation of the pro-apoptotic protein BAD at serine 112, ultimately reducing Bax (Montrer BAX Anticorps) levels and increasing mitochondrial permeability.

  9. a possible coordinated role of VEGF-A (Montrer VEGFA Anticorps) and MMP-2 (Montrer MMP2 Anticorps) during uterine leiomyomas growth and angiogenesis with potential prognostic significance

  10. Results show that TIMP-1 expression is growth pattern dependent in colorectal cancer liver metastases. At the metastasis periphery, TIMP-1 could have MMP inhibitory activity, and in the pericytes it could be involved in tumor angiogenesis.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Decreased MMP-9 (Montrer MMP9 Anticorps) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (Montrer EGF Anticorps) on MMP-9 (Montrer MMP9 Anticorps) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (Montrer TNF Anticorps), and hepatocyte growth factor (Montrer HGF Anticorps) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (Montrer TIMP2 Anticorps) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (Montrer TIMP2 Anticorps) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (Montrer TIMP2 Anticorps) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (Montrer MMP9 Anticorps), TIMP1, and NGAL (Montrer LCN2 Anticorps) (also MMP2 (Montrer MMP2 Anticorps) in 220 kDa complex) without proteolytic activity.

  2. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (Montrer VEGFA Anticorps), pro-MMP-9 (Montrer MMP9 Anticorps), MMP-2 (Montrer MMP2 Anticorps), VEGFR-1 (Montrer FLT1 Anticorps), VEGFR-2 (Montrer KDR Anticorps), and TIMP-1, which may contribute to the development of venous stenosis.

  3. Results indicate that leukemia inhibitory factor (LIF (Montrer LIF Anticorps)) and Oncostatin M (Montrer OSM Anticorps) increase the expression of MMP-1 (Montrer MMP1 Anticorps), MMP-3 (Montrer MMP3 Anticorps), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (Montrer LIF Anticorps) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (Montrer MMP2 Anticorps), MMP-9 (Montrer MMP9 Anticorps) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (Montrer CD63 Anticorps).

  2. TIMP-1 is a ligand of LRP-1 (Montrer LRP1 Anticorps) and we highlight a new example of its MMP-independent, cytokine-like functions.

  3. RAB37 (Montrer RAB37 Anticorps) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (Montrer MMP9 Anticorps) migration axis in vitro and in vivo and to suppress tumor metastasis.

  4. PDGF-D (Montrer PDGFD Anticorps) intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2 (Montrer MMP2 Anticorps)/MMP (Montrer MMP2 Anticorps)-9 (Montrer MMP9 Anticorps) system, and PDGF-D (Montrer PDGFD Anticorps) signaling is mediated through both PDGF (Montrer PDGFA Anticorps)-alpha and -beta receptors.

  5. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (Montrer MAPK14 Anticorps) signaling pathway.

  6. Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 (Montrer TIMP3 Anticorps)-deficient mice.

  7. TNF-alpha (Montrer TNF Anticorps) produced by cholestasis can promote liver fibrosis via TIMP-1 production from hepatic stellate cells.

  8. These data suggest an MMP-independent role of TIMP-1 in regulating CD4 (Montrer CD4 Anticorps) T cell access into the CNS parenchyma during acute JHMV encephalitis

  9. miR (Montrer MLXIP Anticorps)-21 contributes to renal fibrosis by mediating MMP9 (Montrer MMP9 Anticorps)/TIMP1

  10. Gene expression of Mmp-12 (Montrer MMP12 Anticorps) and Mmp-13 (Montrer MMP13 Anticorps), and Timp-1 was strongly upregulated at all time points in RD compared with controls. Timp-2 (Montrer TIMP2 Anticorps), Mmp-2 (Montrer MMP2 Anticorps), and Mmp-9 (Montrer MMP9 Anticorps) expression was modest.

TIMP1 profil antigène

Profil protéine

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Gene names and symbols associated with TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) anticorps
  • TIMP metallopeptidase inhibitor 1 (Timp1) anticorps
  • tissue inhibitor of metalloproteinase 1 (LOC100009047) anticorps
  • tissue inhibitor of metalloproteinase 1 (Timp1) anticorps
  • Clgi anticorps
  • DKFZp468A0912 anticorps
  • EPA anticorps
  • EPO anticorps
  • HCI anticorps
  • Timp anticorps
  • TIMP-1 anticorps
  • TIMP1 anticorps

Protein level used designations for TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPECIES
574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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