Titin (TTN) Kits ELISA

TTN encodes a large abundant protein of striated muscle. De plus, nous expédions Titin Anticorps (57) et Titin Protéines (6) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
TTN 7273 Q8WZ42
TTN 22138  
Anti-Rat TTN TTN 84015  
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Top Titin Kits ELISA sur anticorps-enligne.fr

Showing 9 out of 20 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.113 ng/mL 0.31-20 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$560.00
Détails
Humain 0.78 1.56   96 Tests Connectez-vous pour afficher 2 to 3 Days
$713.90
Détails
Poulet 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Cobaye 0.469 ng/mL 0.781-50 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Souris
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$875.60
Détails

Titin Kits ELISA mieux référencés

  1. Human Titin Kit ELISA pour Sandwich ELISA - ABIN414785 : Li, Li, Wang, Yang: Proteomic analysis of effluents from perfused human heart for transplantation: identification of potential biomarkers for ischemic heart damage. dans Proteome science 2012 (PubMed)

Plus Kits ELISA pour Titin partenaires d'interaction

Human Titin (TTN) interaction partners

  1. Truncating titin mutations cause a mild and treatable form of dilated cardiomyopathy.

  2. Activation of titin protein represents an initial step forward adaptive remodelling of the exercised muscle and may also be involved in the initiation of myofibre repair.

  3. Novel A178D missense mutation in titin is a cause of a highly penetrant familial cardiomyopathy with features of left ventricular noncompaction.

  4. Quantitative models derived from large-scale human genetic and phenotypic data can be applied to truncating mutations in titin in dilated cardiomyopathy.

  5. Variants near TTN and CCDC8 (Montrer CCDC8 Kits ELISA) were associated with KI67 (Montrer MKI67 Kits ELISA) expression, and rs2288563 and rs2562832 in TTN are potential biomarkers for the prediction of clinical outcomes in hepatitis B-related hepatocellular carcinoma patients.

  6. Recent studies classify pathogenic variants in the TTN gene as the main responsible for Familial Dilated Cardiomyopathy.

  7. Heterozygous loss of RBM20 (Montrer RBM20 Kits ELISA) suffices to profoundly impair myocyte biomechanics by its disturbance of TTN splicing causing dilated cardiomyopathy.

  8. Study identified a probable association between variation in TTN gene and patients with sudden unexpected death syndrome.

  9. We report that missense variant in the A-band of TTN gene is the strongest candidate mutation for autosomal-dominant inguinal hernia with incomplete penetrance.

  10. Titin-truncating variant is associated with dilated cardiomyopathy.

Mouse (Murine) Titin (TTN) interaction partners

  1. It is likely that titin plays a role in the increase of active muscle stiffness during rapid unloading. These results are consistent with the idea that, in addition to the thin filaments, titin is activated upon Ca(2 (Montrer CA2 Kits ELISA)+) influx in skeletal muscle.

  2. Titin-based force enhancement in skeletal muscle is essentially absent in muscular dystrophy with myositis sarcomeres where amino acids in N2A and PEVK titin are deleted, indicating these specific regions along titin are paramount in increasing titin stiffness in an active sarcomere.

  3. Our data suggest that Tbeta4 is required for setting correct sarcomere length and for appropriate splicing of titin, not only in the heart but also in skeletal muscle.

  4. Phosphorylating Titin's Cardiac N2B Element by ERK2 (Montrer MAPK1 Kits ELISA) or CaMKIIdelta Lowers the Single Molecule and Cardiac Muscle Force

  5. Cleavage of C-terminal titin by CAPN3 (Montrer CAPN3 Kits ELISA) is associated with limb-girdle muscular dystrophy 2A and tibial muscular dystrophy.

  6. titin affects the tuning of shivering frequency

  7. An increase in the degree of titin phosphorylation results in increased proteolytic degradation of this protein, that contributes to the development of skeletal muscle atrophy.

  8. Pure volume overload induces an increase in titin stiffness that is beneficial and limits eccentric remodeling.

  9. increased titin stiffness promotes myocardial contraction by accelerating the formation of force-generating cross-bridges without decelerating relaxation

  10. alpha-Synemin (Montrer SYNM Kits ELISA) localizes to the M-band of the sarcomere through interaction with the M10 region of titin

Fruit Fly (Drosophila melanogaster) Titin (TTN) interaction partners

  1. Here we show using Drosophila indirect flight muscle that the filamin ortholog Cheerio in conjunction with the giant elastic protein titin plays a crucial role in keeping thin filaments stably anchored at the Z-disc. We identify the filamin domains required for interaction with the titin ortholog Sallimus, and we demonstrate a genetic interaction of filamin with titin and actin.

  2. Sls is a novel hub gene responsible for the regulation of mitochondrial respiration in the muscle sarcomere.

  3. Projectin immunolocalization studies during myofibrillogenesis in Drosophila indirect flight muscles.

  4. Projectin is oriented within the indirect flight muscles sarcomere with its NH2-terminus embedded in the Z-bands. This protein has an elastic region, possibly the PEVK-like domain located close to the NH2-terminus.

  5. Alternative Sls isoforms could regulate the stiffness of the many fibre types in Drosophila muscles.

  6. Results reveal a role for Mlp84B in maintaining muscle structural integrity, and suggest Mlp84B and D-titin cooperate to stabilize muscle sarcomeres.

Cow (Bovine) Titin (TTN) interaction partners

  1. titin may be a factor involved in the Frank-Starling mechanism of the heart by promoting actomyosin interaction in response to stretch

  2. calcium affects passive myocardial tension in a titin isoform-dependent manner.

  3. Upon relaxation of shortened myocytes, the restoring stiffness correlates with the titin isoform expression profile with myocytes that express high levels of the stiff isoform (N2B) having the highest restoring stiffness.

Rabbit Titin (TTN) interaction partners

  1. The results of this study are consistent with the claim that residual force enhancement is present and is regulated by titin in skeletal psoas myofibrils, but not cardiac papillary myofibrils

  2. landscape recovered all features of our nanomechanics results. The ensemble molten-globule dynamics delivers significant added contractility that may assist sarcomere mechanics, and it may reduce the dissipative energy loss associated with titin unfolding/refolding during muscle contraction/relaxation cycles.

  3. Work done by titin protein folding assists muscle contraction.

  4. Suggest that the increase in the static tension in activated striated muscle is directly associated with Ca(2+)-dependent change in titin properties and not associated with changes in titin-actin interactions.

  5. titin's visco-elastic properties appear to depend on the Ig do- main un/refolding kinetics and that indeed, titin (and thus myofibrils) can become virtually elastic when Ig domain un/refolding is prevented.

  6. Under non-equilibrium conditions across the physiological force range, titin extends by a complex pattern of history-dependent discrete conformational transitions.

  7. We tested the hypothesis that titin properties might be reflected well in single myofibrils. mechanics of titin are well preserved in isolated myofibrils.

  8. Titin might be responsible for passive force enhancement observed in myofibrils.

  9. The structure and self-interactive properties of an approximately 290 kDa ( approximately 100 nm long) tryptic fragment from the I-band part of titin that is extensible in situ, is presented.

  10. results suggest residual force enhancement in skeletal muscle fibers is caused by stiffening of titin upon muscle activation but not with titin binding to actin; finding indicates existence of a Ca(2 (Montrer CA2 Kits ELISA)+)-regulated, titin-based stiffness in skeletal muscle

Pig (Porcine) Titin (TTN) interaction partners

  1. Two polymorphisms previously identified and described in the 3'UTR (Montrer UTS2R Kits ELISA) of MYPN (Montrer MYPN Kits ELISA) and TTN genes in a group of Italian Large White (ILW) and Italian Duroc (ID) pigs, were analysed.

  2. Titin-actin interaction: PEVK-actin-based viscosity in a large animal.

  3. Neonatal pig hearts showed large N2BA-titin isoforms distinct from those present in the adult porcine myocardium.

  4. findings demonstrate that Tn plays an important role in the Frank-Starling mechanism of the heart via on-off switching of the thin filament state, in concert with titin-based regulation

  5. Report PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.

  6. Coexpression of the 2 titin isoforms in large mammals allows longer sarcomere lengths without the development of excessive diastolic tension.

Titin (TTN) profil antigène

Antigen Summary

This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma.

Gene names and symbols associated with Titin (TTN) Kits ELISA

  • titin (TTN) anticorps
  • titin (Ttn) anticorps
  • bent (bt) anticorps
  • sallimus (sls) anticorps
  • titin (titin) anticorps
  • titin (TTNLOC100620261) anticorps
  • 0020/01 anticorps
  • 39c-18 anticorps
  • 1100001C23Rik anticorps
  • 2310036G12Rik anticorps
  • 2310057K23Rik anticorps
  • 2310074I15Rik anticorps
  • AF006999 anticorps
  • anon-CREST anticorps
  • AV006427 anticorps
  • Bt anticorps
  • CG1479 anticorps
  • CG1915 anticorps
  • CG10285 anticorps
  • CG18242 anticorps
  • CG18245 anticorps
  • CG18857 anticorps
  • CG32019 anticorps
  • CMD1G anticorps
  • CMH9 anticorps
  • CMPD4 anticorps
  • CT3598 anticorps
  • CT8086 anticorps
  • CT41299 anticorps
  • d-titin anticorps
  • D330041I19Rik anticorps
  • D830007G01Rik anticorps
  • Dmel\\CG1915 anticorps
  • Dmel\\CG32019 anticorps
  • EOMFC anticorps
  • HMERF anticorps
  • ket anticorps
  • kettin anticorps
  • KZ anticorps
  • l(2)2 anticorps
  • l(2)23 anticorps
  • l(3)62Ca anticorps
  • l(3)Ca anticorps
  • l(3)dre8 anticorps
  • l(3)j1D7 anticorps
  • l(3)rL182 anticorps
  • l(3)S002001 anticorps
  • l(4)2 anticorps
  • l(4)21 anticorps
  • l(4)23 anticorps
  • l(4)37 anticorps
  • l(4)38 anticorps
  • l(4)102CDa anticorps
  • l(4)PT-2 anticorps
  • L56 anticorps
  • LGMD2J anticorps
  • MCP anticorps
  • mdm anticorps
  • MYLK5 anticorps
  • Prj anticorps
  • sal anticorps
  • sam anticorps
  • shru anticorps
  • Sls anticorps
  • Titin anticorps
  • TMD anticorps
  • UNC-22 anticorps

Protein level used designations for Titin (TTN) Kits ELISA

connectin , rhabdomyosarcoma antigen MU-RMS-40.14 , C-protein , CG32019-PC , CG32019-PF , CG32019-PH , CG32019-PI , bt-PC , bt-PF , bt-PH , bt-PI , lethal(4) Powell, Tennessee-2 , myosin LCK , projectin , projectin myosin light chain kinase , twitchin , CG1915-PA , CG1915-PD , CG1915-PP , CG1915-PQ , CG1915-PR , CG1915-PS , CG1915-PT , CG1915-PU , CG1915-PV , CG1915-PW , CG1915-PX , CG1915-PY , CG1915-PZ , D-titin , D-titin-KZ , dtitin , kettin , lethal (3) S002001 , lethal(3)62Ca , mitotic chromosomal protein , salimus , sls-PA , sls-PD , sls-PP , sls-PQ , sls-PR , sls-PS , sls-PT , sls-PU , sls-PV , sls-PW , sls-PX , sls-PY , sls-PZ , titin , titin protein homolog

GENE ID SPECIES
7273 Homo sapiens
22138 Mus musculus
43814 Drosophila melanogaster
44013 Drosophila melanogaster
84015 Rattus norvegicus
424126 Gallus gallus
540561 Bos taurus
1791505 Rhodopirellula baltica SH 1
100008570 Oryctolagus cuniculus
100620261 Sus scrofa
100722767 Cavia porcellus
Fournisseurs de qualité sélectionnés pour Titin (TTN) Kits ELISA
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