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anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) Anticorps

The protein encoded by TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. De plus, nous expédions TRPM2 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TRPM2 7226 O94759
TRPM2 28240  
TRPM2 294329  
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Top anti-TRPM2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 80 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Souris Lapin Inconjugué ICC, IHC (fro), IF, IHC, WB Staining of rat hippocampus using ABIN259658. TRPM2 is stained red, GFAP is stained green and nuclei staining is blue. Photo courtesy of Dr. Ji-Zhong Bai, The University of Auckland, New Zealand. 0.1 mL Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Lapin Inconjugué ICC, IF, IP, WB Western Blot: TRPM2 Antibody [ABIN153041] - Membrane Prep (50 ug) from Jurkat cells. Antibody: Affinity purified rabbit anti-TRPM2 antibody used for WB at 2 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué ICC, IHC (fro), IF, IP, IHC, WB   100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué IHC (p), WB Anti-TRPM2 antibody, IHC(P) IHC(P): Rat Brain Tissue Anti-TRPM2 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate Lane 3: Mouse Liver Tissue Lysate Lane 4: JURKAT Cell Lysate Lane 5: HELA Cell Lysate Lane 6: A549 Cell Lysate 100 μg Connectez-vous pour afficher 8 to 11 Days
298,57 €
Détails
Souris Lapin DyLight 550 ICC, IF, IHC, IHC (fro), WB   0.1 mL Connectez-vous pour afficher 3 to 5 Days
476,25 €
Détails
Souris Lapin Inconjugué ICC, IF, WB Detection of TRPM2 in mouse brain membrane lysates using ABIN259771. Immunocytochemistry/Immunofluorescence: TRPM2 Antibody [ABIN2597714] - TRPM2 antibody was tested in Neuro2A cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Humain Lapin Inconjugué IHC (p), IHC, WB Western Blot: TRPM2 Antibody [NBP1-33416] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE, antibody diluted at 1:500. Immunohistochemistry-Paraffin: TRPM2 Antibody [NBP1-33416] - Paraffin-embedded MDAMB468 xenograft, using antibody at 1:100 dilution. 100 μL Connectez-vous pour afficher 3 to 5 Days
426,25 €
Détails
Humain Chèvre Inconjugué IHC (p) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IHC (p), WB Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Heart, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
801,43 €
Détails

TRPM2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine) , , , ,
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anti-TRPM2 Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal TRPM2 Primary Antibody pour ICC, IHC (fro) - ABIN259658 : Bai, Lipski: Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture. dans Neurotoxicology 2010 (PubMed)
    Show all 8 references for ABIN259658

  2. Human Polyclonal TRPM2 Primary Antibody pour ICC, IHC (fro) - ABIN153042 : Partida-Sanchez, Gasser, Fliegert, Siebrands, Dammermann, Shi, Mousseau, Sumoza-Toledo, Bhagat, Walseth, Guse, Lund: Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction. dans Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 4 references for ABIN153042

  3. Human Polyclonal TRPM2 Primary Antibody pour ICC, IF - ABIN153041 : Moreau, Kirchberger, Swarbrick, Bartlett, Fliegert, Yorgan, Bauche, Harneit, Guse, Potter: Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists. dans Journal of medicinal chemistry 2013 (PubMed)
    Show all 2 references for ABIN153041

  4. Mouse (Murine) Polyclonal TRPM2 Primary Antibody pour ICC, IF - ABIN4362934 : Rah, Kwak, Chung, Kim: ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells. dans Scientific reports 2015 (PubMed)

  5. Cow (Bovine) Polyclonal TRPM2 Primary Antibody pour IHC, WB - ABIN2781840 : Hecquet, Ahmmed, Vogel, Malik: Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. dans Circulation research 2008 (PubMed)

Plus d’anticorps contre TRPM2 partenaires d’interaction

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) interaction partners

  1. Study determined the sequence of pig TRPC1 and TRPC3-7 channels and found pig TRPC cDNAs resemble their human homologs more than the others .

  2. heteromeric cation channels comprised of the TRPP2 mutant and the TRPC3 (Montrer TRPC3 Anticorps) or TRPC7 protein induce enhanced receptor-activated Ca(2 (Montrer CA2 Anticorps)+) influx that may lead to dysregulated cell growth in ADPKD

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) interaction partners

  1. Study demonstrate that PRL (Montrer PRL Anticorps) is necessary for the survival of (retinal pigment epithelium) RPE (Montrer RPE Anticorps) under normal and advancing age conditions and, identified SIRT2 (Montrer SIRT2 Anticorps) and TRPM2 (Montrer CLU Anticorps) as molecular targets for the antioxidant and antiapoptotic actions of PRL (Montrer PRL Anticorps) in the RPE (Montrer RPE Anticorps).

  2. TRPM2 (Montrer CLU Anticorps) has a role in the DNA damage response of T cell leukemia cells in a BCL-2 (Montrer BCL2 Anticorps) dependent manner

  3. Data show that HEK293 cells expressing low levels of receptor potential melastatin 2 (TRPM2) chan (Montrer TRPM3 Anticorps)nel wer (Montrer CLU Anticorps)e more susceptible to silica nanoparticles (NPs) than those expressing high levels of TRPM2.

  4. This is expected to provide a basis for inhibiting TRPM2 (Montrer CLU Anticorps) for the improved treatment of breast cancer, which potentially includes treating breast tumors that are resistant to chemotherapy due to their evasion of apoptosis.

  5. In a transgenic mouse model of Alzheimer's disease, TRPM2 (Montrer CLU Anticorps) was involved in neuronal toxicity and memory impairment.

  6. These findings shed new light on the evolution of TRPM2 (Montrer CLU Anticorps) and establish nvTRPM2 as a promising tool to decipher its complex gating mechanisms.

  7. we report here a novel effect promoted by TRPM2 (Montrer CLU Anticorps), where it functions to minimize DNA damage and thus may have a role in the protection of genomic DNA in breast cancer cells.

  8. The HDACi-elicited upregulation of TRPM2 (Montrer CLU Anticorps) expression.

  9. TRPM2 (Montrer CLU Anticorps) actively regulates the phosphorylation of GSK-3 (Montrer GSK3b Anticorps) in the brain.

  10. The degradation of zonula occludens-1 (ZO-1 (Montrer TJP1 Anticorps)), and claudin-2 (Montrer CLDN2 Anticorps) exhibited a great dependence on the activation of the transient receptor potential melastatin (Montrer TRPM1 Anticorps) (TRPM) 2 (Montrer CLU Anticorps) channel, phospholipase Cgamma1 (PLCgamma1 (Montrer PLCG1 Anticorps)) and the protein kinase (Montrer CDK7 Anticorps) Calpha (Montrer PRKACA Anticorps) (PKCalpha (Montrer PKCa Anticorps)) signaling cascade.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) interaction partners

  1. Data show that macrophages from young mice showed lower transient receptor potential melastatin 2 (Montrer TRPM3 Anticorps) (TRPM2) expression than those from senescent mice and had lower viability after silica nanoparticles (NPs (Montrer NPS Anticorps)) exposure than those from senescent ones.

  2. TRPM2 activation is likely to be mediated by ADP-ribose production via PARP (Montrer PARP1 Anticorps) pathway

  3. mice in which TRPM2 had been genetically deleted showed a striking deficit in their sensation of non-noxious warm temperatures, consistent with the idea that TRPM2 initiates a 'warm' signal which drives cool-seeking behaviour

  4. findings provide compelling evidence that F. tularensis catalase (Montrer CAT Anticorps) restricts reactive oxygen species to temper macrophage TRPM2-mediated Ca(2 (Montrer CA2 Anticorps)+) signaling and limit host immune function.

  5. TRPM2 plays roles in a wide range of pathological pain models based on peripheral and central neuroinflammation, rather than physiological nociceptive pain.

  6. The findings provide evidence for a mechanism by which Abeta (Montrer APP Anticorps) impairs neurovascular regulation and suggest that TRPM2 channels are a potential therapeutic target to counteract cerebrovascular dysfunction in Alzheimer's dementia.

  7. Neointimal hyperplasia was substantially reduced in Trpm2 knockout mice.

  8. endogenous redox signals in pancreatic beta cells elevate insulin (Montrer INS Anticorps) secretion via TRPM2 sensitization and activity at body temperature

  9. These results provide the first evidence to show a critical role for TRPM2 channel activation during reperfusion in the delayed increase in the [Zn(2+)]c and CA1 (Montrer CA1 Anticorps) pyramidal neuronal death.

  10. Postischemic neovascularization in mice required reactive oxygen species generation in endothelial cells and resultant TRPM2 activation.

TRPM2 profil antigène

Profil protéine

The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Gene names and symbols associated with TRPM2

  • transient receptor potential cation channel, subfamily M, member 2 (TRPM2) anticorps
  • transient receptor potential cation channel, subfamily M, member 2 (trpm2) anticorps
  • transient receptor potential cation channel, subfamily M, member 2 (Trpm2) anticorps
  • 9830168K16Rik anticorps
  • C79133 anticorps
  • EREG1 anticorps
  • KNP3 anticorps
  • LTRPC2 anticorps
  • NUDT9H anticorps
  • NUDT9L1 anticorps
  • si:ch73-263b18.1 anticorps
  • Trp7 anticorps
  • TRPC7 anticorps
  • TRPM2 anticorps
  • Trpm2-predicted anticorps
  • Trrp7 anticorps

Protein level used designations for TRPM2

transient receptor potential cation channel, subfamily M, member 2 , transient receptor potential cation channel, subfamily C, member 7 , transient receptor potential cation channel, subfamily C, member 7-like , short transient receptor potential channel 7-like , transient receptor potential cation channel subfamily M member 2-like , transient receptor potential channel subfamily C member 7 , LTrpC-2 , estrogen-responsive element-associated gene 1 protein , long transient receptor potential channel 2 , transient receptor potential cation channel subfamily M member 2 , transient receptor potential channel 7 , transient receptor protein 7 , transient receptor potential melastatin family 2

GENE ID SPECIES
424835 Gallus gallus
470101 Pan troglodytes
703611 Macaca mulatta
799412 Danio rerio
100056810 Equus caballus
100083361 Ornithorhynchus anatinus
100124999 Xenopus (Silurana) tropicalis
100341596 Oryctolagus cuniculus
100443123 Pongo abelii
100479298 Ailuropoda melanoleuca
100479364 Ailuropoda melanoleuca
100539776 Meleagris gallopavo
100556895 Anolis carolinensis
100271727 Sus scrofa
7226 Homo sapiens
28240 Mus musculus
294329 Rattus norvegicus
508029 Bos taurus
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