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Suppressor of apoptosis. De plus, nous expédions Transmembrane BAX Inhibitor Motif Containing 6 Kits (6) et et beaucoup plus de produits pour cette protéine.
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BI-1 affects cell death-associated components localized in sphingolipid-enriched microdomains of the plasma membrane.
AtBI-1 contributes to synthesis of sphingolipids during cold stress by interacting with AtSLD1, AtFAH1, AtSBH2 and AtADS2.
Arabidopsis thaliana BI-1-interacting proteins were identified.
The role of AtBI1 over-expression in delaying Methyl jasmonate-induced leaf senescence by suppressing the [Ca(2 (Montrer CA2 Anticorps)+)](cyt (Montrer CYGB Anticorps))-dependent activation of MPK6 (Montrer MAPK6 Anticorps), thus providing a new insight into the function and mechanism of AtBI1 in plant senescence.
Overexpression of AtBI-1 increases the amount of 2-hydroxy fatty acids.
BAX INHIBITOR 1 is an attenuator for cell death progression triggered by both biotic and abiotic types of cell death signals in Arabidopsis.
The expression of AtBI-1, which suppresses Bax (Montrer BAX Anticorps)-induced cell death, in the tapetum at the tetrad stage inhibits tapetum degeneration and subsequently results in pollen abortion, while activation of AtBI-1 at the later stage does not.
A study evaluating the effect of AtBI-1 on calcium homeostasis is reported.
BI-1 requires normal electron transport activity to suppress cell death in yeast
Results indicate that the loss of calmodulin (Montrer CALM Anticorps) binding reduces the cell death suppressor activity of Bax inhibitor-1 in planta.
BI-1 is overexpressed and promotes the progression and metastasis of non-small cell lung cancer
These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2 (Montrer CA2 Anticorps)) homeostasis in a wide variety of tissues
Bax inhibitor-1 is likely a pH-sensitive calcium leak channel, not a H+/Ca2 (Montrer CA2 Anticorps)+ exchanger.
BI-1 enhances glucose metabolism, leading to high activation of the sodium/hydrogen exchange for intracellular pH homeostasis.
Results highlight the regulatory role of BI-1 in idiopathic pulmonary fibrosis.
The effect of Bax Inhibitor-1(TMBIM6) as a regulatorof endoplasmic reticulum Ca2 (Montrer CA2 Anticorps)+ homeostasis is regulated by intracellular pH by removing negative charges.
Constructed lentivirus expression vector for transfecting BI-1.
Data indicate that GAAP (Montrer HIVEP1 Anticorps) and BI-1 have a six membrane-spanning topology with cytosolic N and C termini and a C-terminal reentrant loop.
The results reveal BI-1 as a novel autophagy regulator that bridges Ca(2 (Montrer CA2 Anticorps)) signaling between ER and mitochondria, reducing cellular oxygen consumption and contributing to cellular resilience in the face of metabolic stress.
The C terminus of Bax inhibitor-1 forms a Ca2 (Montrer CA2 Anticorps)+-permeable channel pore.
An endogenous protective role of BI-1 under conditions of chronic mild stress.
BI-1-induced ERK1/2 (Montrer MAPK1/3 Anticorps) activation plays an important role in the modulation of intracellular reactive oxygen species generation and apoptotic cell death and may also affect autoimmune response.
BI-1-mediated enhancement of lysosomal activity regulates P450 (Montrer POR Anticorps) 2E1 expression and resultant ROS (Montrer ROS1 Anticorps) accumulation
highly maintained lysosomal activity may be one of the mechanisms by which BI-1 exerts its regulatory effects on the ER stress response and cell death.
A critical role of BI-1 as a stress integrator that modulates autophagy levels and other interconnected homeostatic processes.
BI-1 reduces endoplasmic reticulum (ER) stress and provides protection from acute brain injury via modulation of several ER-associated functions, including unfolded protein response signaling.
BI-1 may confer affective resiliency in multiple animal models of depression and anhedonia
Suppressor of apoptosis
bax inhibitor 1
, testis enhanced gene transcript
, testis-enhanced gene transcript protein
, transmembrane BAX inhibitor motif-containing protein 6
, Bax inhibitor-1
, testis enhanced gene transcript (BAX inhibitor 1)