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TRIM13 encodes a member of the tripartite motif (TRIM) family. De plus, nous expédions TRIM13 Anticorps (60) et TRIM13 Protéines (5) et beaucoup plus de produits pour cette protéine.
TRIM13 mediated NF-kappaB (Montrer NFKB1 Kits ELISA) repression is essential for negative regulation of clonogenic ability of the cells.
Results show that HRD1 (Montrer SYVN1 Kits ELISA) and RFP2 contributes are required for the disposal of V247M alpha-sarcoglycan (Montrer SGCA Kits ELISA) mutant.
This study first time demonstrated the role of TRIM13 as novel regulator of caspase-8 (Montrer CASP8 Kits ELISA) activation and cell death during endoplasmic reticulum stress.
Shows important roles of TRIM13 in MM tumour survival and proliferation in multiple myeloma.
Results describe the role of TRIM13 in induction of autophagy, which may play an important role in regulation of ER stress and tumor suppression.
Data suggest that irradiation causes RFP2 overexpression, which enhances ionizing radiation-induced apoptosis by increasing p53 (Montrer TP53 Kits ELISA) stability and decreasing AKT (Montrer AKT1 Kits ELISA) kinase activity through MDM2 (Montrer MDM2 Kits ELISA) and AKT (Montrer AKT1 Kits ELISA) degradation.
Rfp2 contains a C-terminal transmembrane domain indispensable for its localization to the ER
TRIM13, also known as RFP2, promoter area contains multiple quadruplex forming GGGGA-repeats that possesses unusually hight activity, anomalously high electrostatic fields induced by sequence-dependent dipoles and very low nucleosome forming potential.
these data identify Trim13 as a positive regulator of NF-kappaB (Montrer NFKB1 Kits ELISA) activation and suggest that lysine 29-linked polyubiquitination is a specific ubiquitin-linked pattern involved in the control of TLR2 (Montrer TLR2 Kits ELISA) signaling.
TRIM13 interacts with MDA5 (Montrer IFIH1 Kits ELISA) and negatively regulates MDA5 (Montrer IFIH1 Kits ELISA)-mediated type I IFN production.
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
tripartite motif-containing 13
, ret finger protein 2
, B-cell chronic lymphocytic leukemia tumor suppressor Leu5
, CLL-associated RING finger
, E3 ubiquitin-protein ligase TRIM13
, RING finger protein 77
, leukemia-associated protein 5
, putative tumor suppressor RFP2
, tripartite motif protein 13
, tripartite motif-containing protein 13