Tripeptidyl Peptidase II (Tpp2) Kits ELISA

Tpp2 encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. De plus, nous expédions Tpp2 Anticorps (15) et Tpp2 Protéines (3) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain Tpp2 Tpp2 7174 P29144
Anti-Souris Tpp2 Tpp2 22019 Q64514
Anti-Rat Tpp2 Tpp2 81815 Q64560
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Plus Kits ELISA pour Tpp2 partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  2. a systematic kinetic analysis of wild type Drosophila melanogaster TPPII and five point mutants of the double-Glu (Montrer SLC2A1 Kits ELISA)-motif (E312/E343) involving natural substrates were performed.

  3. The structure suggests a model for activation of TPP II involving the relocation of a flexible loop and a repositioning of the active-site serine, coupling it to holocomplex assembly and active-site sequestration.

  4. The 150 kDa subunits of TPPII form a superstructure composed of 2 segmented & twisted (Montrer POMT2 Kits ELISA) strands. Each strand is 12.5 nm in width & composed of 11 segments that enclose a central channel.

  5. the unique spindle form of the holo-complex of TPP II represents an assembly motif stabilizing a highly active state

Arabidopsis thaliana Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. The purification and characterization of tripeptidyl peptidase II from Arabidopsis thaliana is reported.

Human Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. Novel interactions of TPPII, p53 (Montrer TP53 Kits ELISA), and SIRT7 (Montrer SIRT7 Kits ELISA) presented in this study might contribute to the knowledge of the regulatory effects of these proteins on apoptotic pathways and to the understanding mechanisms of aging and lifespan regulation.

  2. TPP2 mediates many important cellular functions by controlling ERK1 (Montrer MAPK3 Kits ELISA) and ERK2 (Montrer MAPK1 Kits ELISA) phosphorylation.

  3. Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with TPP2 deficiency have been described in two consanguineous siblings.

  4. Study found that autosomal recessive TPP2 mutations cause recurrent infections, autoimmunity, and neurodevelopmental delay in humans.

  5. TPPII, MYBBP1A (Montrer MYBBP1A Kits ELISA) and CDK2 (Montrer CDK2 Kits ELISA) form a protein-protein interaction network.

  6. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  7. Study showed that overexpression of Tripeptidyl peptidase II (TPP2) occurs frequently during oral carcinogenesis and might be associated with the progression of Oral Squamous Cell Carcinoma (OSCC) via Spindle Assembly Checkpoint(SAC (Montrer ADCY10 Kits ELISA)) activation.

  8. obtained a 3D structure of the human TPPII

  9. Current knowledge about TPPII with a focus on structural aspects.

  10. Results suggest an important function of TPPII in the maintenance of viral growth and may have implications for anti-viral therapy.

Mouse (Murine) Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. Data indicate that TPPII can regulate sperm maturation by modulating intracellular Ca(2 (Montrer CA2 Kits ELISA)+) stores via the type 3 RyR (Montrer RYR1 Kits ELISA).

  2. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  3. Tripeptidyl peptidase II is crucial for nucleoprotein epitope generation during major histocompatibility complex class I complex viral antigen processing both in the presence and absence of lactacystin-sensitive proteasome action.

  4. TPPII is not generally required for the production of major histocompatibility class I-restricted peptides, but presentation of some peptides can be negatively affected by TPPII.

  5. Data show that mice that were homozygous for an insertion in the Tpp2 locus were embryonic lethal and Tpp2 heterozygous mutants were lean compared with wild-type littermates, although food intake was normal.

  6. The data suggest a moderate, predominantly destructive role of TPPII in class I Ag processing.

  7. TPPII is important for maintaining normal cellular and systemic physiology, which may be relevant for potential therapeutic applications of TPPII inhibitors

  8. These results do not support a generally important role of TPPII for viability and proliferation of transformed cells or their p53 (Montrer TP53 Kits ELISA)-mediated DNA damage response.

  9. These data indicate that while TPPII contributes to the trimming of peptides with very long N-terminal extensions, TPPII is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (Montrer GLA Kits ELISA) in vivo.

Tpp2 profil antigène

Antigen Summary

This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase\; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.

Gene names and symbols associated with Tpp2

  • tripeptidyl-peptidase II (TppII) anticorps
  • tripeptidyl peptidase II (TPP2) anticorps
  • tripeptidyl peptidase II (tpp2) anticorps
  • tripeptidyl peptidase ii (AaeL_AAEL007174) anticorps
  • tripeptidyl peptidase ii (AaeL_AAEL009516) anticorps
  • tripeptidyl peptidase ii (AaeL_AAEL010192) anticorps
  • tripeptidyl peptidase II (LOC100359134) anticorps
  • tripeptidyl peptidase II (Tpp2) anticorps
  • anon-WO0118547.127 anticorps
  • CG3991 anticorps
  • DKFZp468E2313 anticorps
  • Dmel\\CG3991 anticorps
  • dTPP II anticorps
  • dTPPII anticorps
  • l(2)k14301 anticorps
  • MGC83244 anticorps
  • T13K14.10 anticorps
  • T13K14_10 anticorps
  • TPP-2 anticorps
  • TPP2 anticorps
  • TPP II anticorps
  • TppII anticorps
  • tripeptidyl peptidase ii anticorps

Protein level used designations for Tpp2

CG3991-PA , CG3991-PD , TppII-PA , TppII-PD , Tripeptidyl-peptidase II , tripeptidyl peptidase II , tripeptidylpeptidase II , tripeptidyl peptidase ii , tripeptidyl-peptidase 2 , TPP-II , tripeptidyl aminopeptidase , tripeptidyl-peptidase II

GENE ID SPECIES
36444 Drosophila melanogaster
428020 Gallus gallus
443806 Xenopus laevis
827833 Arabidopsis thaliana
5568882 Aedes aegypti
5572106 Aedes aegypti
5572975 Aedes aegypti
100101674 Xenopus (Silurana) tropicalis
100172493 Pongo abelii
100359134 Oryctolagus cuniculus
100552517 Anolis carolinensis
7174 Homo sapiens
22019 Mus musculus
81815 Rattus norvegicus
526052 Bos taurus
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