anti-Troponin T2, Cardiac (TNNT2) Anticorps

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. De plus, nous expédions Cardiac Troponin T2 Kits (72) et Cardiac Troponin T2 Protéines (36) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
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Top anti-Cardiac Troponin T2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 383 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of cTnT expression in H9 (A), 4T1 (B), human heart (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Cat Souris Inconjugué EIA, IHC (p), IP, WB 50 μg Connectez-vous pour afficher 6 to 8 Days
$500.50
Détails
Poulet Souris Inconjugué IF, IHC (p) Human Rabbit Heart (formalin-fixed, paraffin-embedded) stained with TNNT2 antibody ABIN462337 followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Lapin Inconjugué IHC (p), IHC, WB   0.2 mL Connectez-vous pour afficher 7 to 9 Days
$408.19
Détails
Poulet Souris Inconjugué IF, IHC (p) 250 μL Connectez-vous pour afficher 7 to 9 Days
$676.50
Détails
Cat Souris Inconjugué IHC (p), ELISA Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Cat Souris Inconjugué IHC (p), ELISA Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Souris Inconjugué EIA, WB 0.2 mg Connectez-vous pour afficher 6 to 8 Days
$401.50
Détails

TNNT2 Anticorps par réactivité, application, clonalité et conjugué

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anti-Cardiac Troponin T2 Anticorps mieux référencés

  1. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody pour ICS - ABIN2688864 : Jáchymová, Muravská, Paleček, Kuchynka, Řeháková, Magage, Kr��l, Zima, Horký, Linhart: Genetic variation screening of TNNT2 gene in a cohort of patients with hypertrophic and dilated cardiomyopathy. dans Physiological research / Academia Scientiarum Bohemoslovaca 2012 (PubMed)
    Show all 7 Pubmed References

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody pour IHC (f), ICS - ABIN2688865 : Lian, Hsiao, Wilson, Zhu, Hazeltine, Azarin, Raval, Zhang, Kamp, Palecek: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. dans Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 7 Pubmed References

  3. Fish Monoclonal Cardiac Troponin T2 Primary Antibody pour ELISA (Detection), ELISA - ABIN191344 : Feng, Taggart, Hall, Bryant, Sansone, Kemmerer, Herlich, Lord: Limited additional release of cardiac troponin I and T in isoproterenol-treated beagle dogs with cardiac injury. dans Clinical chemistry 2005 (PubMed)
    Show all 6 Pubmed References

  4. Mammalian Monoclonal Cardiac Troponin T2 Primary Antibody pour ELISA (Capture), ELISA - ABIN191341 : Goette, Arndt, Röcken, Staack, Bechtloff, Reinhold, Huth, Ansorge, Klein, Lendeckel: Calpains and cytokines in fibrillating human atria. dans American journal of physiology. Heart and circulatory physiology 2002 (PubMed)
    Show all 6 Pubmed References

  5. Fish Monoclonal Cardiac Troponin T2 Primary Antibody pour ELISA, WB - ABIN191342 : Hammerer-Lercher, Erlacher, Bittner, Korinthenberg, Skladal, Sorichter, Sperl, Puschendorf, Mair: Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy. dans Clinical chemistry 2001 (PubMed)
    Show all 6 Pubmed References

  6. Mammalian Monoclonal Cardiac Troponin T2 Primary Antibody pour ELISA (Detection), ELISA - ABIN191349 : Nakaura, Morimoto, Yanaga, Nakata, Nishi, Imaizumi, Ohtsuki: Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy. dans The American journal of physiology 1999 (PubMed)
    Show all 6 Pubmed References

  7. Cow (Bovine) Monoclonal Cardiac Troponin T2 Primary Antibody pour ELISA (Detection), ELISA - ABIN191346 : Urasawa, Wada, Machida, Yuasa, Shimatsu, Wakao, Yuasa, Sano, Nonaka, Nakamura, Takeda: Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. dans Circulation 2008 (PubMed)
    Show all 6 Pubmed References

  8. Cow (Bovine) Monoclonal Cardiac Troponin T2 Primary Antibody pour ELISA (Capture), ELISA - ABIN191348 : van den Berg, Abu-Issa, de Boer, Hutson, de Boer, Soufan, Ruijter, Kirby, van den Hoff, Moorman: A caudal proliferating growth center contributes to both poles of the forming heart tube. dans Circulation research 2009 (PubMed)
    Show all 6 Pubmed References

Plus d’anticorps contre Cardiac Troponin T2 partenaires d’interaction

Human Troponin T2, Cardiac (TNNT2) interaction partners

  1. Among patients with chest pain and stable troponin levels, any detectable level of high-sensitivity cardiac troponin is associated with an increased risk of death and cardiovascular disease.

  2. High-sensitivity cTnT measurement increases the detection of perioperative myocardial infarction.

  3. In a heart failure cohort, high sensitivity troponin T serum levels had very significant prognostic value.

  4. Asymptomatic cTnT elevation might be strongly associated with all-cause and cardiovascular mortality in dialysis patients without diabetic nephropathy.

  5. Higher postoperative concentrations of high-sensitivity troponin T are independently associated with all-cause mortality in patients undergoing on-pump cardiac surgery.

  6. variants in TNNT2 and BAG3 (Montrer BAG3 Anticorps) are associated with a high propensity to life-threatening cardiomyopathy presenting from childhood and young adulthood.

  7. Binding of the MBNL (Montrer MBNL1 Anticorps) zinc fingers to cardiac troponin T pre-mRNA is specific and relatively simple, unlike the complex multiple dimer-trimer stoichiometries postulated in some previous studies.

  8. The measurement of high-sensitivity cardiac troponin T plasma concentration within large nationally-representative surveys such as the Health Survey for England is feasible.

  9. Data suggest that modulation of structural dynamics far from the regulatory Ca2 (Montrer CA2 Anticorps)+-binding site is the underlying molecular mechanism for many TNNC1 (Montrer TNNC1 Anticorps) mutations in patients with hypertrophic cardiomyopathies or familial hypertrophic cardiomyopathies; many mutations affect balance between open and closed conformations; troponin I switch peptide [TnI (Montrer TNNI2 Anticorps)(SW)] switch peptide binds to TNNC1 (Montrer TNNC1 Anticorps) and stabilizes the open TNNC1 (Montrer TNNC1 Anticorps) conformation.

  10. Data suggest that the tropomyosin (Montrer TPM2 Anticorps) overlap region structure and function are affected differentially by a point mutation in cardiac tropomyosin (TPM1, D230N) that is associated with dilated cardiomyopathy as compared to a point mutation in cardiac troponin T (TNNT2, R92L) that is associated with hypertrophic cardiomyopathy.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Significant changes in thin filament Ca2 (Montrer CA2 Anticorps)+-sensitivity, structure and kinetics are brought about through PKC (Montrer PKC Anticorps) phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) interaction partners

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. TnTA30V mutation attenuated Ca(2 (Montrer CA2 Anticorps)+)-activated maximal tension and length-mediated cross-bridge recruitment against alpha-myosin (Montrer MYH6 Anticorps) heavy chain but augmented these parameters against beta-myosin heavy chain (Montrer MYH7 Anticorps), suggesting divergent contractile phenotypes.

  2. The shift from cTnT exon 5 inclusion to exclusion during development was delayed in the heart of Ts65Dn mice due to Dyrk1A (Montrer DYRK1A Anticorps) overexpression.

  3. for hypertrophic cardiomyopathy (HCM)-causing mutations in TnT (Montrer TNNI1 Anticorps), Ca(2 (Montrer CA2 Anticorps)+)-sensitisation together with uncoupling in vitro is the usual response and both factors may contribute to the HCM phenotype

  4. cardiomyopathy mutation (R97L) in mouse cardiac troponin T has an effect on the muscle length-mediated recruitment of crossbridges and is modified divergently by alpha- and beta-myosin heavy chain (Montrer MYH7 Anticorps)

  5. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  6. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  7. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  8. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  9. TnT (Montrer TNNI1 Anticorps) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (Montrer MYH6 Anticorps) and hypertrophic cardiomyopathy in the presence of MYH7 (Montrer MYH7 Anticorps).

  10. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

Zebrafish Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (Montrer TNNI1 Anticorps), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (Montrer TPM2 Anticorps)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (Montrer TNNI1 Anticorps) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) profil antigène

Profil protéine

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene names and symbols associated with TNNT2

  • troponin T type 2 (cardiac) (TNNT2) anticorps
  • troponin T2, cardiac (Tnnt2) anticorps
  • troponin T type 2 (cardiac) (Tnnt2) anticorps
  • troponin T type 2 (cardiac) (tnnt2) anticorps
  • troponin T2a, cardiac (tnnt2a) anticorps
  • CMH2 anticorps
  • CMPD2 anticorps
  • CT3 anticorps
  • cTnT anticorps
  • Ctt anticorps
  • CTTG anticorps
  • LVNC6 anticorps
  • RATCTTG anticorps
  • RCM3 anticorps
  • tnnt2 anticorps
  • Tnnt3 anticorps
  • Tnt anticorps
  • TnTC anticorps

Protein level used designations for TNNT2

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPECIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
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