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TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. De plus, nous expédions Tyrosinase-Related Protein 1 Protéines (15) et Tyrosinase-Related Protein 1 Kits (3) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 201 products:
Human Polyclonal Tyrosinase-Related Protein 1 Primary Antibody pour ICC, IF - ABIN409307
Raphaël, Lehenkyi, Vandenberghe, Beck, Khalimonchyk, Vanden Abeele, Farsetti, Germain, Bokhobza, Mihalache, Gosset, Romanin, Clézardin, Skryma, Prevarskaya: TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival. dans Proceedings of the National Academy of Sciences of the United States of America 2014
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Human Polyclonal Tyrosinase-Related Protein 1 Primary Antibody pour IF (p), IHC (p) - ABIN1714403
Cui, Song, Geng, Ding, Qin, Fan, Dong, Geng: The expression of KRT2 and its effect on melanogenesis in alpaca skins. dans Acta histochemica 2016
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Cow (Bovine) Polyclonal Tyrosinase-Related Protein 1 Primary Antibody pour WB - ABIN2781813
Forshew, Khaliq, Tee, Smith, Johnson, Mehdi, Maher: Identification of novel TYR and TYRP1 mutations in oculocutaneous albinism. dans Clinical genetics 2005
Cow (Bovine) Polyclonal Tyrosinase-Related Protein 1 Primary Antibody pour IHC, WB - ABIN2781815
Horibe, Satoh, Shiota, Kumagai, Horike, Takemori, Uesato, Sugie, Obata, Kawahara, Nagaoka: Induction of melanogenesis by 4'-O-methylated flavonoids in B16F10 melanoma cells. dans Journal of natural medicines 2013
a mutation in tyrp1A, one of the two tyrp1 paralogs in zebrafish, causes melanophore death leading to a semi-dominant phenotype
The Fugu tyrp1 promoter can direct transgene expression in a cell-type-specific manner in zebrafish. Our findings provide evidence supporting differential regulations of melanin-synthesizing genes in RPE (Montrer RPE Anticorps) cells and the NCDM in zebrafish.
we identified some genes that are related to fur formation, including Tyrosinase-related protein 1 (TYRP1) and Tyrosinase (TYR (Montrer TYR Anticorps)), as well as genes with unknown functions.
A mutation in exon 2 of the TYRP1 gene leads to a premature stop codon at position 190 of the deduced amino acid sequence. Genotyping 203 rabbits of 32 different breeds identified this mutation only in brown Havana rabbits.
DNA sequencing showed that the patient has carried compound heterozygous mutations of the tyrosinase related protein (TYRP1) gene, namely c.1214C>A (p.T405N) and c.1333dupG, which were inherited from his mother and father, respectively.
Single nucleotide polymorphisms in TYRP1 gene is associated with multiple primary melanoma.
Mutation in TYRP1 is associated with oculocutaneous albinism.
Polymorphisms in 3'UTR (Montrer UTS2R Anticorps) of TYRP1 mRNA can affect TYRP1 mRNA regulation by miR (Montrer MLXIP Anticorps)-155 and its subsequent translation into protein. These SNPs can render TYRP1 mRNA and protein expression nonsusceptible to miR (Montrer MLXIP Anticorps)-155 activity
These data suggest that UVB-stimulated Ucn1 (Montrer UCN Anticorps) contributes to TRP1 (Montrer PRSS1 Anticorps) production via the transcription of both Nurr-1 (Montrer NR4A2 Anticorps) and Nur77 (Montrer NR4A1 Anticorps). Ucn1 (Montrer UCN Anticorps), produced in melanoma cells, acts on melanoma cells themselves in an autocrine manner.
These data indicate that galectin-3 (Montrer LGALS3 Anticorps) is a regulatory component in melanin synthesis affecting the expression of Tyrp-1.
p53 (Montrer TP53 Anticorps) regulation by TRP2 (Montrer DCT Anticorps) is not pervasive in melanoma.
Due to mutation in Tyrp1 protein, it became more rigid and might disturb the structural conformation and catalytic function of the structure and might also play a significant role in inducing oculocutaneous albinism type III.
in human melanoma HMV-II cells both CRF (Montrer CRH Anticorps) and Ucn1 (Montrer UCN Anticorps) regulate TRP1 (Montrer PRSS1 Anticorps) gene expression via Nurr-1 (Montrer NR4A2 Anticorps)/Nur77 (Montrer NR4A1 Anticorps) production, independent of pro-opiomelanocortin (Montrer POMC Anticorps) or alpha-melanocyte-stimulating hormone (Montrer POMC Anticorps) stimulation.
High TYRP1/S100B (Montrer S100B Anticorps) mRNA expression in lymph node metastases from melanoma patients is associated with unfavourable clinical outcome.
A 6-bp deletion in the TYRP1 gene causes the brown colouration phenotype in Chinese indigenous pigs.
Sequence analysis revealed variation in the TYRP1 (exon 5) and MC1R (Montrer MSHR Anticorps) genes; restriction enzyme analysis of these two genes could distinguish between different colours of Hanwoo cattle.
Genetic modulators of IOP thus may be independently identified using the full array of BXD mice without concern for the presence of transillumination defect or mutations in Typr1 and/or Gpnmb.
the results from the present study demonstrate that the MA extract increases melanogenesis through the upregulation of TRP-1 (Montrer TRPC1 Anticorps) protein expression by post-transcriptional control in B16F10 cells
Studied upregulation by Kaliziri extract of tyrosinase (Montrer TYR Anticorps), TRP-1 (Montrer TRPC1 Anticorps), TRP-2 (Montrer DCT Anticorps) and MITF (Montrer MITF Anticorps) expression in murine B16 melanoma cells.
The SNARE (Montrer VTI1B Anticorps) machinery composed of VAMP7 (Montrer VAMP7 Anticorps) on Tyrp1-containing vesicles and syntaxin-3 (Montrer STX3 Anticorps) and SNAP23 (Montrer SNAP23 Anticorps) on melanosomes regulates Tyrp1 trafficking to the melanosome in melanocytes.
Addition of a TRP-1 (Montrer TRPC1 Anticorps)-directed monoclonal antibody to the treatment protocol for B16F10 skin melanoma mediates eradication of subcutaneous lesions.
analysis of tyrosinase-related protein 1 in mouse melanocytes at early embryonic stage
GILT (Montrer IFI30 Anticorps)-deficient mice have an increase in TRP1 (Montrer TRPC1 Anticorps)-specific regulatory T (Treg) cells compared with TRP1 (Montrer TRPC1 Anticorps)-deficient mice, and depletion of Treg cells partially restores the ability of GILT (Montrer IFI30 Anticorps)-deficient TRP1 (Montrer TRPC1 Anticorps)-specific CD4 (Montrer CD4 Anticorps)(+) T cells to induce vitiligo (Montrer MITF Anticorps).
The Tyrp1b mutation modifies the pathways and gene networks in which Tyrp1 functions.
DNA vaccination with a melanoma-shared antigen Trp1 (Montrer TRPC1 Anticorps), combined with systemic TGF-beta (Montrer TGFB1 Anticorps) blockade during the perioperative period of primary tumor resection, confers protection against B16 melanoma.
both the Rab32 (Montrer RAB32 Anticorps)/38 binding activity and VAMP7 (Montrer VAMP7 Anticorps) binding activity of Varp (Montrer ANKRD27 Anticorps) are essential for trafficking of Tyrp1 in melanocytes but activation of Rab21 (Montrer RAB21 Anticorps) by the VPS9 domain is not necessary for Tyrp1 trafficking
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
5,6-dihydroxyindole-2-carboxylic acid oxidase
, tyrosinase-related protein 1
, 5,6-dihydroxyindole-2-carboxylic acid oxidase-like
, short transient receptor potential channel 1
, transient receptor protein 1
, DHICA oxidase
, catalase B
, glycoprotein 75
, melanoma antigen gp75
, tyrosinase-related protein-1
, brown locus protein
, iris stromal atrophy
, tyrosine phosphatase 1, same as B (Brown)