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Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. De plus, nous expédions USP10 Protéines (4) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal USP10 Primary Antibody pour IHC (p), IP - ABIN258188
Simpson-Holley, Kedersha, Dower, Rubins, Anderson, Hensley, Connor: Formation of antiviral cytoplasmic granules during orthopoxvirus infection. dans Journal of virology 2011
Show all 2 Pubmed References
Investigate the expression of USP10 in the human normal adrenal gland and various adrenal tumors. In adrenal tumors, detectable levels of USP10 protein were found in 100 % (30/30) adrenocortical adenomas, 88.89 % (8/9) adrenocortical carcinomas, and 10 % (2/20) pheochromocytomas.
G3BP (Montrer G3BP1 Anticorps) mediates the condensation of stress granules by shifting between two different states that are controlled by the phosphorylation of S149 and by binding to Caprin1 or USP10.
Data demonstrated that AMPK (Montrer PRKAA1 Anticorps)-USP10 form a positive feedforward loop that ensures amplification of AMPK (Montrer PRKAA1 Anticorps) activation in response to fluctuation of cellular energy status.
miR (Montrer MLXIP Anticorps)-191 could promote pancreatic cancer progression through targeting USP10, implicating a novel mechanism for the tumorigenesis.
USP10 deubiquitinates and stabilizes SIRT6 (Montrer SIRT6 Anticorps).
this study identified USP10, a carboxyl-terminal ubiquitin-processing protease, could interact with T-bet in the nucleus.
USP10 inhibits genotoxic NF-kappaB (Montrer NFKB1 Anticorps) activation by MCPIP1 (Montrer ZC3H12A Anticorps)-facilitated deubiquitination of NEMO (Montrer IKBKG Anticorps).
USP10 is a host factor that inhibits stress-induced reactive oxygen species production and apoptosis in HTLV-1-infected T cells.
USP10 mediates the deubiquitination of p53 (Montrer TP53 Anticorps), regulating deubiquitination activity of USP10 and USP13 (Montrer USP13 Anticorps) by Beclin1 (Montrer BECN1 Anticorps) provides a mechanism for Beclin1 (Montrer BECN1 Anticorps) to control the levels of p53 (Montrer TP53 Anticorps).
a novel function for USP10 in facilitating the deubiquitination of CFTR (Montrer CFTR Anticorps) in early endosomes, thereby enhancing the endocytic recycling and cell surface expression of CFTR (Montrer CFTR Anticorps).
Thus, modulating the levels of both Huwe1 and USP10 appears to fine-tune the requisite degradation of TBP (Montrer TBP Anticorps) during myogenesis.
vasopressin (Montrer AVP Anticorps)-induced Usp10 deubiquitylates and stabilizes endogenous SNX3 (Montrer SNX3 Anticorps) and consequently promotes cell surface expression of ENaC (Montrer SCNN1A Anticorps) in kidney
Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene.
putative universal stress protein
, ubiquitin specific peptidase 10
, ubiquitin specific protease 10
, ubiquitin carboxyl-terminal hydrolase 10
, Deubiquitinating enzyme 10
, Ubiquitin thioesterase 10
, Ubiquitin-specific-processing protease 10
, ubiquitin thiolesterase 10
, ubiquitin carboxyl-terminal hydrolase 10-like
, deubiquitinating enzyme 10
, ubiquitin thioesterase 10
, ubiquitin-specific-processing protease 10
, ubiquintin c-terminal hydrolase related polypeptide
, Deubiquitinating enzyme 10-A
, Ubiquitin thioesterase 10-A
, Ubiquitin-specific-processing protease 10-A
, ubiquitin carboxyl-terminal hydrolase 10-A
, ubiquitin thiolesterase 10-A