Unc-45 Homolog B (C. Elegans) (UNC45B) Kits ELISA

UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002 [PubMed 12356907]).[supplied by OMIM, Mar 2008].. De plus, nous expédions UNC45B Anticorps (41) et UNC45B Protéines (3) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Souris UNC45B UNC45B 217012 Q8CGY6
Anti-Humain UNC45B UNC45B 146862 Q8IWX7
Anti-Rat UNC45B UNC45B 303373  
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Plus Kits ELISA pour UNC45B partenaires d'interaction

Mouse (Murine) Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. UNC-45B and Hsp90 (Montrer HSP90 Kits ELISA) involved in sarcomere function

  2. vertebrate Unc45 isoforms clearly demonstrates a direct role for Unc45 in Hsp90-mediated myosin motor domain folding and highlights major differences between the isoforms in substrate specificity and mechanism

  3. mammalian Unc45b is a cytosolic protein that forms a stable complex with Hsp90, selectively binds the unfolded conformation of the myosin motor domain, and promotes motor domain folding

Human Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract (Montrer MIP Kits ELISA) developing in early childhood.

  2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range.

Zebrafish Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. The transcriptional up-regulation of unc45b, hsp90aa1.1 and smyd1b is specific to zebrafish mutants with myosin folding defects, and is not triggered in other zebrafish myopathy models

  2. Results indicate co-expression and co-regulation of Unc45b and non-muscle myosins (NMMs) in myogenic tissue.

  3. There is no functional redundancy between Unc45a (Montrer UNC45A Kits ELISA) and Unc45b in vivo.

  4. Steif/Unc-45b interacts with the chaperone Hsp90a (Montrer HSP90AA1 Kits ELISA) in vitro. The two genes are co-expressed in the skeletal musculature.

  5. In response to stress or damage to the myofiber, Unc45b and Hsp90a dissociate from the Z line and transiently associate with myosin.

Pig (Porcine) Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. Different genotypes of the CMYA4 gene are significantly associated with the backfat thickness of the area between sixth and seventh ribs (p < 0.05) and backfat thickness at the shoulder (p < 0.05).

UNC45B profil antigène

Antigen Summary

UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002

Gene names and symbols associated with UNC45B

  • unc-45 myosin chaperone B S homeolog (unc45b.S) anticorps
  • unc-45 myosin chaperone B (unc45b) anticorps
  • unc-45 myosin chaperone B (UNC45B) anticorps
  • unc-45 myosin chaperone B (Unc45b) anticorps
  • AA445617 anticorps
  • cb393 anticorps
  • CMYA4 anticorps
  • D230041A13Rik anticorps
  • MGC80931 anticorps
  • SMUNC45 anticorps
  • Unc-45B anticorps
  • UNC45 anticorps
  • unc45r anticorps
  • wu:fa05a03 anticorps
  • wu:fa10f03 anticorps
  • wu:fb37f02 anticorps
  • wu:fb96f06 anticorps
  • wu:fc10f04 anticorps

Protein level used designations for UNC45B

unc-45 homolog B , sarcomeric myosin heavy chain chaperone , unc-45 homolog B (C. elegans) , protein unc-45 homolog B-like , UNC-45B , cardiomyopathy associated 4 , protein unc-45 homolog B , striated muscle UNC45 , UNC45-related protein , fb37f02 , unc-45B , cardiomyopathy-associated 4

447296 Xenopus laevis
493194 Xenopus (Silurana) tropicalis
715419 Macaca mulatta
100483697 Ailuropoda melanoleuca
100586571 Nomascus leucogenys
217012 Mus musculus
146862 Homo sapiens
303373 Rattus norvegicus
480606 Canis lupus familiaris
100715234 Cavia porcellus
266640 Danio rerio
535385 Bos taurus
417527 Gallus gallus
100058135 Equus caballus
100134956 Sus scrofa
100346230 Oryctolagus cuniculus
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