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Vac14 Homolog (S. Cerevisiae) (VAC14) Kits ELISA

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. De plus, nous expédions VAC14 Anticorps (14) et VAC14 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain VAC14 VAC14 55697 Q08AM6
Anti-Souris VAC14 VAC14 234729 Q80WQ2
Anti-Rat VAC14 VAC14 307842 Q80W92
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Plus Kits ELISA pour VAC14 partenaires d'interaction

Human Vac14 Homolog (S. Cerevisiae) (VAC14) interaction partners

  1. Rab7 GAP TBC1D15 (Montrer TBC1D15 Kits ELISA) with Vac14.

  2. a novel regulatory mechanism whereby ArPIKfyve enhances Sac3 abundance by attenuating Sac3 proteasome-dependent degradation and suggest that a failure of this mechanism could be the primary molecular defect in the pathogenesis of CMT4J.

  3. the PIKfyve (Montrer PIKFYVE Kits ELISA)-associated hVac14 protein has a major role in activating PIKfyve (Montrer PIKFYVE Kits ELISA) and thereby regulating PtdIns(3,5)P(2) synthesis and endomembrane homeostasis in mammalian cells

  4. describe a novel interaction between the PDZ domain (Montrer INADL Kits ELISA) of nitric oxide synthase (Montrer NOS Kits ELISA) and Vac14

  5. demonstrate a coupling between the machinery for PtdIns(3,5)P2 synthesis and turnover achieved through a physical assembly of PIKfyve, ArPIKfyve, and Sac3.

  6. The authors data indicate that the PAS (Montrer PASK Kits ELISA) complex is organized to provide optimal PIKfyve (Montrer PIKFYVE Kits ELISA) functionality and is maintained via ArPIKfyve homomeric and heteromeric interactions.

  7. PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis

Mouse (Murine) Vac14 Homolog (S. Cerevisiae) (VAC14) interaction partners

  1. Thus, VAC14, PI(3,5)P(2) and/or PI(5)P play a role in controlling postsynaptic function via regulation of endocytic cycling of AMPA (Montrer GRIA3 Kits ELISA) receptors.

  2. a novel regulatory mechanism whereby ArPIKfyve enhances Sac3 abundance by attenuating Sac3 proteasome-dependent degradation and suggest that a failure of this mechanism could be the primary molecular defect in the pathogenesis of CMT4J.

  3. The data demonstrate for the first time a physical association between functionally related PIKfyve (Montrer PIKFYVE Kits ELISA) and ArPIKfyve in 3T3-L1 adipocytes.

  4. report the characterization of a mouse mutant lacking Vac14, a regulator of PI(3,5)P(2) synthesis

  5. The authors show that Vac14 exerts an effect as a scaffold for the PI(3,5)P2 regulatory complex by direct contact with the known regulators of PI(3,5)P2: Fig4, Fab1, Vac7 and Atg18 (Montrer WIPI1 Kits ELISA).

VAC14 profil antigène

Antigen Summary

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007

Gene names and symbols associated with VAC14

  • Vac14 homolog (vac14) anticorps
  • Vac14 homolog (S. cerevisiae) (VAC14) anticorps
  • Vac14 homolog (S. cerevisiae) (Vac14) anticorps
  • AA959718 anticorps
  • ArPIKfyve anticorps
  • BC032215 anticorps
  • D8Wsu151e anticorps
  • ingls anticorps
  • Tax1bp2 anticorps
  • Trx anticorps

Protein level used designations for VAC14

protein VAC14 homolog , Tax1 (human T-cell leukemia virus type I) binding protein 1 , Tax1 (human T-cell leukemia virus type I) binding protein 2 , tax1-binding protein 2 , vacuole morphology 14 , vacuole 14 protein

GENE ID SPECIES
447315 Xenopus laevis
55697 Homo sapiens
234729 Mus musculus
307842 Rattus norvegicus
533202 Bos taurus
415678 Gallus gallus
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