Zyxin (ZYX) Kits ELISA

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. De plus, nous expédions Zyxin Anticorps (86) et Zyxin Protéines (9) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ZYX 7791 Q15942
ZYX 22793 Q62523
Anti-Rat ZYX ZYX 114636  
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Humain 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
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Humain 0.061 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 8 to 12 Days
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Plus Kits ELISA pour Zyxin partenaires d'interaction

Caenorhabditis elegans (C. elegans) Zyxin (ZYX) interaction partners

  1. ZYX-1 is a conserved LIM (Montrer PDLIM5 Kits ELISA) domain-containing focal adhesion protein that regulates synapse maintenance in Caenorhabditis elegans

  2. The zyx-1 gene encodes two different isoforms, ZYX-1a and ZYX-1b, which exhibit different roles in dystrophin (Montrer DMD Kits ELISA)-dependent muscle degeneration in C. elegans

  3. DYC-1 interacts with ZYX-1, the homologue of the vertebrate focal adhesion LIM domain protein (Montrer PDLIM7 Kits ELISA) zyxin.

Fruit Fly (Drosophila melanogaster) Zyxin (ZYX) interaction partners

  1. results show that Zyxin is a functional antagonist of Expanded in growth control

  2. The motor domain of DmMyo20 could specifically bind to actin (Montrer ACTB Kits ELISA) filaments in an ATP-independent manner and enhance the interaction between actin (Montrer ACTB Kits ELISA) filaments and Zyx102, a downstream component of DmMyo20 in the Fat signaling pathway.

  3. Through epistasis tests, the requirement for Zyx is positioned within the Fat branch of Hippo signaling, downstream of Fat and Dco (Montrer CSNK1E Kits ELISA), and upstream of the Yorkie (Montrer YAP1 Kits ELISA) kinase Warts.

  4. Reduction of Zyx102 protein levels using RNA-interference results in lethality at the pharate adult stage.

Human Zyxin (ZYX) interaction partners

  1. Increased zyxin expression is associated with asthma.

  2. VASP (Montrer VASP Kits ELISA), zyxin and TES (Montrer TES Kits ELISA) are tension-dependent members of focal adherens junctions independent of the alpha-catenin (Montrer CTNNA1 Kits ELISA)-vinculin (Montrer VCL Kits ELISA) module.

  3. Zyxin binding to Ptc2 is due to the interaction of Zyxin 2nd LIM-domain (530-590 aa) with the under-membrane region of the cytoplasmic C-terminus of Ptc2 (1159-1412 aa).

  4. ZYX gene may be aging-related gene and involved in Osteoporosis.

  5. Matrix density alters zyxin phosphorylation, which limits peripheral process formation and extension in endothelial cells invading 3D collagen matrices.

  6. Zyxin, which is thought to be essential for tight cell-to-cell junctions, decreased 1.8-fold in TNF-alpha (Montrer TNF Kits ELISA)-treated human brain microvascular endothelial cells.

  7. Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta.

  8. Zyxin is a novel target for beta-amyloid peptide (Montrer APP Kits ELISA) activities in Alzheimer's disease.

  9. Zyxin is suggested to promote growth, migration and invasiveness of fibroblastic type oral squamous cell carcinoma cells by upregulating Rac1 and Cdc42 (Montrer CDC42 Kits ELISA).

  10. A stretch-induced signaling pathway in vascular cells leads to the activation of zyxin, a cytoskeletal protein (Montrer ACTN1 Kits ELISA) specifically involved in transducing mechanical stimuli.

Mouse (Murine) Zyxin (ZYX) interaction partners

  1. zyxin influences focal adhesion dynamics, that it recruits Tes (Montrer TES Kits ELISA) and that this interaction is functional in regulating cell spreading.

  2. Zyxin contributes to the migratory and invasive phenotype evoked by Tead2.

  3. Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta.

  4. paxillin (Montrer PXN Kits ELISA) and zyxin are LIM (Montrer PDLIM5 Kits ELISA)-domain adaptor proteins that are recruited to stress fiber strain sites

  5. Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1beta.

  6. Zyxin is a transforming growth factor-beta (TGF-beta)/Smad3 (Montrer SMAD3 Kits ELISA) target gene that regulates lung cancer cell motility via integrin alpha5beta1.

  7. a bipartite mechanism for stretch-induced actin remodeling involves mechanosensitive targeting of zyxin to actin stress fibers and localized recruitment of actin regulatory machinery

  8. Mice that lack zyxin function are viable and fertile and display no obvious histological abnormalities in any of the organs examined.Specifically, we evaluated blood platelet function, nervous system development, and skin architecture

  9. LIM-nebulette (Montrer NEBL Kits ELISA), Lasp-1 (Montrer LASP1 Kits ELISA), and zyxin may play an important role in the organization of focal adhesions

  10. Cooperates with Ena, vasodilator-stimulated phosphoprotein, and caldesmon to influence integrin-dependent cell motility and actin stress fiber remodeling.

Xenopus laevis Zyxin (ZYX) interaction partners

  1. Zyxin binding to Ptc2 is due to the interaction of Zyxin 2nd LIM-domain (530-590 aa) with the under-membrane region of the cytoplasmic C-terminus of Ptc2 (1159-1412 aa).

  2. Zyxin inhibits Shh (Montrer SHH Kits ELISA) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1 (Montrer GLI1 Kits ELISA)

  3. These results are consistent with a possible role of Zyxin as a negative modulator of Xanf1 transcriptional repressing activity.

  4. binding of the LIM2 domain of zyxin with the Engrailed Homology 1 repressor domain of Xanf1 is responsible for the interaction of these proteins.

Zyxin (ZYX) profil antigène

Antigen Summary

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Gene names and symbols associated with Zyxin (ZYX) Kits ELISA

  • Zyxin (zyx-1) anticorps
  • Zyxin (Zyx) anticorps
  • zyxin (zyx) anticorps
  • zyxin (ZYX) anticorps
  • zyxin (EDI_201420) anticorps
  • zyxin (Zyx) anticorps
  • zyxin S homeolog (zyx.S) anticorps
  • 9530098H06Rik anticorps
  • BcDNA:LD06023 anticorps
  • CG32018 anticorps
  • DLim-1 anticorps
  • Dmel\\CG32018 anticorps
  • DmLIM-1 anticorps
  • ESP-2 anticorps
  • HED-2 anticorps
  • lim anticorps
  • Lim102EF anticorps
  • MGC145270 anticorps
  • R75157 anticorps
  • zgc:171680 anticorps
  • zyx anticorps
  • zyx102 anticorps
  • Zyx102EF anticorps
  • zyxin anticorps

Protein level used designations for Zyxin (ZYX) Kits ELISA

ZYXin family member (zyx-1) , CG32018-PA , CG32018-PB , CG32018-PG , CG32018-PH , Zyx-PA , Zyx-PB , Zyx-PG , Zyx-PH , Zyx102EF , zyxin , hypothetical protein LOC779718 , zyxin-2

GENE ID SPECIES
174951 Caenorhabditis elegans
317824 Drosophila melanogaster
564246 Danio rerio
706407 Macaca mulatta
779718 Xenopus (Silurana) tropicalis
5914189 Entamoeba dispar SAW760
100011992 Monodelphis domestica
100219276 Taeniopygia guttata
7791 Homo sapiens
768226 Bos taurus
22793 Mus musculus
114636 Rattus norvegicus
482736 Canis lupus familiaris
100524720 Sus scrofa
418300 Gallus gallus
100049724 Xenopus laevis
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