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The protein encoded by RHOBTB1 belongs to the Rho family of the small GTPase superfamily. De plus, nous expédions RHOBTB1 Protéines (5) et RHOBTB1 Kits (1) et beaucoup plus de produits pour cette protéine.
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we found that miR (Montrer MLXIP Anticorps)-31 acts as an oncogene (Montrer RAB1A Anticorps) in colon cancer and identified RhoBTB1 as a new target of miR (Montrer MLXIP Anticorps)-31 further study demonstrated that miR (Montrer MLXIP Anticorps)-31 contributed to the development of colon cancer at least partly by targeting RhoBTB1.
Frequent allelic loss and decreased expression of RHOBTB1 suggested that this gene has a role in tumorigenesis of a subset of HNSCC (Head-Neck Squamous Cell Carcinoma).
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants.
rho-related BTB domain-containing protein 1
, Rho-related BTB domain containing 1
, rho-related BTB domain-containing protein 1-like