Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. De plus, nous expédions serine/threonine Kinase 24 Anticorps (89) et serine/threonine Kinase 24 Protéines (13) et beaucoup plus de produits pour cette protéine.
Showing 2 out of 4 products:
CCM3 (Montrer PDCD10 Kits ELISA) signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.
Mst3b, a neuron-specific homolog of the yeast kinase Ste20, is critical for axon outgrowth. Mst3b is activated in response to trophic factors, and suppressing its expression
High MST3 expression is associated with breast cancer.
This study demonistrated that MST3 kinase phosphorylates TAO1 (Montrer TAOK2 Kits ELISA)/2 to enable Myosin Va (Montrer MYO5A Kits ELISA) function in promoting spine synapse development.
This review notes that in the SOK1 (Montrer STK25 Kits ELISA) and MST4 germinal center kinase (Montrer MAP4K2 Kits ELISA) III family of proteins, exon 1 encodes a 5' untranslated region, but this is not the case for MST3.
These data provide molecular understanding of the mechanism by which MO25 (Montrer CAB39 Kits ELISA) isoforms regulates the activity of STE20 family protein kinases.
results show that a STRADalpha-rac1-PAK1 (Montrer PAK1 Kits ELISA) pathway regulates cell polarity and invasion in LKB1 (Montrer STK11 Kits ELISA)-null cells. It also suggests that while the function of LKB1 (Montrer STK11 Kits ELISA) and STRADalpha undoubtedly overlap, they may also have mutually exclusive roles
mechanism of regulation of MST3
Striatin orchestrates the regulation of Mst3 by PP2A.
Mst3 is up-regulated and plays an important role in hypoxia-induced apoptosis of human trophoblasts.
five crystal structures of the catalytic domain of MST3 are presented, including a complex with ADP and manganese, a unique cofactor preferred by the enzyme, and a complex with adenine.
Proteolytic activation of Mst3 by caspases.
Mst3 phosphorylates RhoA (Montrer RHOA Kits ELISA) at Ser26, thereby negatively regulating the activity of RhoA (Montrer RHOA Kits ELISA) in neurons.
STK24 appears to suppress exocytosis by interacting and competing with UNC13D (Montrer UNC13D Kits ELISA) C2B domain for lipid binding, whereas CCM3 (Montrer PDCD10 Kits ELISA) has dual roles in exocytosis regulation.
The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3\; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2\; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000
serine/threonine kinase 24 (STE20 homolog, yeast)
, serine/threonine-protein kinase 24
, STE20-like kinase 3
, STE20-like kinase MST3
, mammalian STE20-like protein kinase 3
, sterile 20-like kinase 3
, mammalian sterile twenty 3 kinase