Aperçu des produits pour anti-Cathepsin K (CTSK) Anticorps

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anti-Cathepsin K Anticorps (CTSK)
Chez www.anticorps-enligne.fr sont 176 Cathepsin K (CTSK) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions Cathepsin K Kits (77) et Cathepsin K Protéines (51) et beaucoup plus de produits pour cette protéine. Un total de 315 Cathepsin K produits sont actuellement listés.
Synonymes:
26/29kD-proteinase, AI323530, anon-SAGE:Wang-123, catK, CG8947, CTS02, CTSK, CTSO, CTSO1, CTSO2, Dmel\\CG8947, l(3)s3635, MMS10-Q, Ms10q, OC-2, PKND, PYCD, wu:fa95f03, wu:fb08b05, zgc:110367

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anti-Cathepsin K Anticorps mieux référencés

  1. Human Polyclonal Cathepsin K Primary Antibody pour EIA, IHC (p) - ABIN951065 : Novinec, Kovacic, Lenarcic, Baici: Conformational flexibility and allosteric regulation of cathepsin K. dans The Biochemical journal 2010 (PubMed)
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  2. Mouse (Murine) Polyclonal Cathepsin K Primary Antibody pour IHC, WB - ABIN3022539 : Xiao, Junfeng, Tianhong, Lu, Shulin, Yu, Xiaohua, Weixia, Sheng, Yanyun, Guo, Min: Cathepsin K in adipocyte differentiation and its potential role in the pathogenesis of obesity. dans The Journal of clinical endocrinology and metabolism 2006 (PubMed)
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  3. Chicken Polyclonal Cathepsin K Primary Antibody pour IP, IHC - ABIN223282 : López-Guisa, Cai, Collins, Yamaguchi, Okamura, Bugge, Isacke, Emson, Turner, Shankland, Eddy: Mannose receptor 2 attenuates renal fibrosis. dans Journal of the American Society of Nephrology : JASN 2012 (PubMed)
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  4. Human Polyclonal Cathepsin K Primary Antibody pour EIA, ELISA - ABIN409081 : Asagiri, Hirai, Kunigami, Kamano, Gober, Okamoto, Nishikawa, Latz, Golenbock, Aoki, Ohya, Imai, Morishita, Miyazono, Kato, Saftig, Takayanagi: Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. dans Science (New York, N.Y.) 2008 (PubMed)

  5. Human Polyclonal Cathepsin K Primary Antibody pour EIA, WB - ABIN452891 : Lendeckel, Kähne, Ten Have, Bukowska, Wolke, Bogerts, Keilhoff, Bernstein: Cathepsin K generates enkephalin from beta-endorphin: a new mechanism with possible relevance for schizophrenia. dans Neurochemistry international 2009 (PubMed)

Plus d’anticorps contre Cathepsin K partenaires d’interaction

Horse (Equine) Cathepsin K (CTSK) interaction partners

  1. CatK inhibition in horses did affect bone marrow nucleated cells other than mature osteoclasts rendering them hypo-responsive to both TLR4 (Montrer TLR4 Anticorps)- and TLR9 (Montrer TLR9 Anticorps)-induced inflammation, predicting a proteolytic activity for CatK within the MyD88 (Montrer MYD88 Anticorps) pathway and/or the following proteolytic events required for the cytokines secretion.

Zebrafish Cathepsin K (CTSK) interaction partners

  1. components of the large latent TGFss complex were identified as novel targets of cathepsin K at neutral pH.

Human Cathepsin K (CTSK) interaction partners

  1. Cathepsin K cleavage of SDF-1alpha inhibits its chemotactic activity towards glioblastoma stem-like cells.

  2. Increased cathepsin K expression in skull base chordoma was associated with tumor invasion and reduced progression free survival.

  3. Immunohistochemistry confirmed cathepsin K protein was expressed in lymphangioleiomyomatosis but not control lungs. Cathepsin K gene expression and protein and protease activity were detected in lymphangioleiomyomatosis -associated fibroblasts but not the LAM (Montrer TSC1 Anticorps) cell line 621-101.

  4. The allosteric site of cathepsin K has been modified by site-directed mutagenesis, and it was shown that it is involved in specific regulation of the collagenolytic activity of cathepsin K.

  5. Cathepsin K and osteocalcin (Montrer BGLAP Anticorps) plasma levels may be suggested as the significant markers of osteopoenia/osteoporosis. In addition, cathepsin K plasma level can be also a valuable marker of severe Coronary Atherosclerosis and Coronary Artery Calcification .

  6. Six mutations in CTSK were identified in 33 families with pycnodysostosis. The high frequency of pycnodysostosis in Ceara State is the consequence of the high inbreeding in that region.

  7. The above studies not only demonstrated that CTSK was widely expressed in tooth-related cells (including odonto- clasts, periodontal ligament cells, pulp cells and odonto- blasts), but also indicated that CTSK was closely related to the development of tissues in oral and maxillofacial region as well as occurrence and development of many oral diseases.

  8. This mutation (c.480_481insT), (p.L160fsX173) is a novel frameshift mutation. The index case extends the phenotypic spectrum and the list of previously reported mutations in the CTSK gene.

  9. There is an increase in levels of CATK in type 1 Gaucher patients compared to the control group. In the patient group, CATK showed higher levels in patients with bone damage compared to those without it.

  10. elevated levels of CatK are closely associated with the presence of chronic heart failure and that the measurement of circulating CatK provides a noninvasive method of documenting and monitoring the extent of chronic heart failure

Pig (Porcine) Cathepsin K (CTSK) interaction partners

  1. The CTSK marker was associated with back fat thickness and lean cuts (P < 0.01), and average daily gain and feed:gain ratio (P < 0.05) estimated breeding values.

Rabbit Cathepsin K (CTSK) interaction partners

  1. The authors showed CTSK upregulation in human lung specimens and elevated serum CTSK levels of patients with tuberculosis, compared with controls.

  2. Down-regulation of cathepsin K in synovium at the initial stage of osteoarthritis significantly accelerated cartilage degeneration.

Mouse (Murine) Cathepsin K (CTSK) interaction partners

  1. This study established a possible role of CatK in TLR7 (Montrer TLR7 Anticorps) proteolytic activation, Treg immunosuppressive activity, and lupus autoimmunity and pathology.

  2. catK deficiency almost completely blunted the increased vascular remodeling response of apoE (Montrer APOE Anticorps)-/- mice to flow cessation, possibly by correcting hyperlipidemia-associated pro-inflammatory effects on the peripheral immune response

  3. The effects of muscarinic receptor (Montrer CHRM5 Anticorps) M3 knockout on cathepsin K expression, bone density and biomechanical properties of bone are reported.

  4. Cathepsin K expression is increased in the bone of a diabetic mouse model.

  5. Data suggest Ctsk gene, key gene upregulated during osteoclast differentiation, is transcriptionally activated during cell hypoxia-induced mitochondrial dysfunction/disruption; hnRNPA2 (heterogeneous ribonucleoprotein A2) is coactivator in this process.

  6. cathepsin K knockout attenuates age-related decline in cardiac function via suppressing caspase (Montrer CASP3 Anticorps)-dependent and caspase (Montrer CASP3 Anticorps)-independent apoptosis

  7. Data (including data from studies in knockout/transgenic mice) suggest that Ctsk is involved in inflammatory response and bone resorption in both rheumatoid arthritis and periodontitis; thus, Ctsk appears to play a role in osteoimmune responses.

  8. In a mouse model of post-traumatic osteoarthritis, cathepsin K activity was significantly increased in injured knees relative to uninjured knees.

  9. Gene deletion of cathepsin K in mice accelerated callus size resolution, significantly increased callus mineralized mass, and improved mechanical strength as compared to wild type mice.

  10. synergism between HIV proteins and pro-atherogenic shear stress to increase endothelial cell expression of the powerful protease cathepsin K

Cathepsin K (CTSK) profil antigène

Antigen Summary

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Alternative names and synonyms associated with Cathepsin K (CTSK)

  • cathepsin K-like (LOC100054991) anticorps
  • 26-29kD-proteinase (26-29-p) anticorps
  • cathepsin K (CTSK) anticorps
  • cathepsin K (ctsk) anticorps
  • Cathepsin K (catk) anticorps
  • cathepsin O (CTSO) anticorps
  • cathepsin K (catk) anticorps
  • cathepsin K (Ctsk) anticorps
  • 26/29kD-proteinase anticorps
  • AI323530 anticorps
  • anon-SAGE:Wang-123 anticorps
  • catK anticorps
  • CG8947 anticorps
  • CTS02 anticorps
  • CTSK anticorps
  • CTSO anticorps
  • CTSO1 anticorps
  • CTSO2 anticorps
  • Dmel\\CG8947 anticorps
  • l(3)s3635 anticorps
  • MMS10-Q anticorps
  • Ms10q anticorps
  • OC-2 anticorps
  • PKND anticorps
  • PYCD anticorps
  • wu:fa95f03 anticorps
  • wu:fb08b05 anticorps
  • zgc:110367 anticorps

Protein level used designations for anti-Cathepsin K (CTSK) Anticorps

26,29kDa proteinase , 26-29 kD-proteinase , 26-29-p-PA , 26-29kDa proteinase , 26-29kd prot , CG8947-PA , anon-SAGE:Wang-123 , cathepsin K , etID33526.16 , Cathepsin K , cathepsin O , cathepsin O1 , cathepsin O2 , cathepsin X , JTAP-1 , protein OC-2 , Cat K , minisatellite 10q detected by probe MMS10 , cathepsin K (pycnodysostosis) , cathepsin K preproprotein

GENE ID SPECIES
100054991 Equus caballus
39547 Drosophila melanogaster
457278 Pan troglodytes
550475 Danio rerio
779889 Xenopus (Silurana) tropicalis
100127265 Xenopus laevis
100195370 Salmo salar
461567 Pan troglodytes
482665 Canis lupus familiaris
616804 Bos taurus
699868 Macaca mulatta
100528180 Ictalurus punctatus
1513 Homo sapiens
395818 Gallus gallus
397569 Sus scrofa
100009334 Oryctolagus cuniculus
13038 Mus musculus
29175 Rattus norvegicus
608843 Canis lupus familiaris
513038 Bos taurus
100718267 Cavia porcellus
101108972 Ovis aries
574112 Macaca mulatta
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