Aperçu des produits pour anti-HCK (HCK) Anticorps

Full name:
anti-Hemopoietic Cell Kinase Anticorps (HCK)
Chez www.anticorps-enligne.fr sont 146 Hemopoietic Cell Kinase (HCK) Anticorps de 19 de différents fournisseurs disponibles. De plus, nous expédions HCK Protéines (16) et HCK Kits (8) et beaucoup plus de produits pour cette protéine. Un total de 183 HCK produits sont actuellement listés.
Synonymes:
AI849071, Bmk, HCK, Hctk, JTK9, laloo, MGC107870, p56Hck, p59Hck, p61Hck

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anti-HCK Anticorps mieux référencés

  1. Dog (Canine) Monoclonal HCK Primary Antibody pour IF, IP - ABIN967877 : Baumgartner, Angelisová, Setterblad, Mooney, Werling, Horejsí, Langsley: Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes. dans Blood 2003 (PubMed)
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  2. Human Polyclonal HCK Primary Antibody pour EIA, WB - ABIN359984 : Komuro, Yokota, Yasuda, Iwamoto, Kagawa: CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection. dans The Journal of experimental medicine 2003 (PubMed)
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  3. Human Polyclonal HCK Primary Antibody pour FACS, IHC (p) - ABIN652384 : Hassan, Suzu, Hiyoshi, Takahashi-Makise, Ueno, Agatsuma, Akari, Komano, Takebe, Motoyoshi, Okada: Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms. dans Journal of cellular physiology 2009 (PubMed)
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  4. Human Polyclonal HCK Primary Antibody pour IF, ELISA - ABIN1531606 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... dans Nature 2002 (PubMed)
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  5. Human Polyclonal HCK Primary Antibody pour WB - ABIN392099 : Stanglmaier, Warmuth, Kleinlein, Reis, Hallek: The interaction of the Bcr-Abl tyrosine kinase with the Src kinase Hck is mediated by multiple binding domains. dans Leukemia 2003 (PubMed)
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  6. Human Monoclonal HCK Primary Antibody pour IHC, ELISA - ABIN969187 : Schnoor: What I learned in Europe.... dans Environmental science & technology 2007 (PubMed)
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Plus d’anticorps contre HCK partenaires d’interaction

Human Hemopoietic Cell Kinase (HCK) interaction partners

  1. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck-dependent activation of PKCdelta (Montrer PKCd Anticorps), which stimulates PKCgamma (Montrer PRKCG Anticorps), resulting in translocation of phosphorylated p47(phox).

  2. HCK represents a novel target for therapeutic development in MYD88 (Montrer MYD88 Anticorps)-mutated Waldenstrom macroglobulinemia and activated-B cell diffuse large B-cell lymphoma, and possibly other diseases driven by mutated MYD88 (Montrer MYD88 Anticorps).

  3. High HCK levels correlate with reduced survival of colorectal cancer patients and is associated with activated macrophages gene signature.

  4. three-dimensional (3D) QSAR pharmacophore models were generated for Hck based on experimentally known inhibitors. A best pharmacophore model, Hypo1, was developed with high correlation coefficient (0.975), Low RMS deviation (0.60) and large cost difference (49.31), containing three ring aromatic and one hydrophobic aliphatic feature

  5. we provide evidence for involvement of HCK and FGR (Montrer FGR Anticorps) in FCRL4 (Montrer FCRL4 Anticorps)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (Montrer FCRL4 Anticorps) molecule.

  6. Interaction with the Src (Montrer SRC Anticorps) homology (SH3-SH2) region of the Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.

  7. Interaction between Nef and Hck is important for Nef-dependent modulation of viral infectivity.

  8. Data indicate that combined treatment using SFK (LYN (Montrer LYN Anticorps), HCK, or FGR (Montrer FGR Anticorps)) and c-KIT (Montrer KIT Anticorps) inhibitor dasatinib dasatinib and chemotherapy provides a novel approach to increasing p53 (Montrer TP53 Anticorps) activity and enhancing targeting of acute myeloid leukemia (Montrer BCL11A Anticorps) (AML (Montrer RUNX1 Anticorps)) stem cells.

  9. The SRC (Montrer SRC Anticorps) family tyrosine kinase (Montrer TXK Anticorps) HCK and the ETS (Montrer ETS1 Anticorps) family transcription factors SPIB (Montrer SPIB Anticorps) and EHF (Montrer EHF Anticorps) regulate transcytosis across a human follicle-associated epithelium model.

  10. This particular binding mode enables Hck SH3 to sense a specific non-canonical residue situated in the SH3 RT-loop of the kinase.

Mouse (Murine) Hemopoietic Cell Kinase (HCK) interaction partners

  1. the Hck, Fgr (Montrer FGR Anticorps) and Lyn (Montrer LYN Anticorps) kinases are also necessary for amastigote uptake by macrophages. Src (Montrer SRC Anticorps)-mediated Arg activation is required for efficient uptake.

  2. Hematopoietic Hck promotes tumorigenesis.

  3. Data suggest that Hck is a key mediator of renal fibrosis

  4. Data indicate that Src (Montrer SRC Anticorps)-Family Kinases Hck and Fgr (Montrer FGR Anticorps) regulate cytokine secretion by macrophages.

  5. Hck is not only progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability.

  6. The Src (Montrer SRC Anticorps) family kinases Hck, Fgr (Montrer FGR Anticorps), and Lyn (Montrer LYN Anticorps) are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

  7. tyrosine phosphorylation of WASP (Montrer WASL Anticorps) by Hck is required for proper macrophage functions

  8. Hck is one of the very few effectors of preosteoclast recruitment described to date and thereby plays a critical role in bone remodeling.

  9. Despite possessing enhanced killing, alveolar macrophage Hck/Fgr (Montrer FGR Anticorps)/Lyn (Montrer LYN Anticorps)-deficient ("triple-knockout") mice do not demonstrate enhanced inflammatory responses to Pneumocystis murina.

  10. Taken together, PKR (Montrer EIF2AK2 Anticorps) and Hck were critical for DON-induced ribosomal recruitment of p38 (Montrer CRK Anticorps), its subsequent phosphorylation, and, ultimately, p38 (Montrer CRK Anticorps)-driven proinflammatory cytokine expression.

Cow (Bovine) Hemopoietic Cell Kinase (HCK) interaction partners

  1. A truncated, mRNA-encoded src-related tyrosine kinase (Montrer FRK Anticorps) HCK could function as an adaptor protein or as a competitive inhibitor in spermiogenesis or mature sperm functions.

  2. the presence of mRNAs encoding for hck and hck-tr in testicular germ cells; hck-tr being translated during spermatogenesis and expressed on mature ejaculated bull spermatozoa.

HCK profil antigène

Antigen Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Alternative names and synonyms associated with HCK

  • hemopoietic cell kinase (tklal-a) anticorps
  • hemopoietic cell kinase (HCK) anticorps
  • hemopoietic cell kinase (hck) anticorps
  • hemopoietic cell kinase (Hck) anticorps
  • AI849071 anticorps
  • Bmk anticorps
  • HCK anticorps
  • Hctk anticorps
  • JTK9 anticorps
  • laloo anticorps
  • MGC107870 anticorps
  • p56Hck anticorps
  • p59Hck anticorps
  • p61Hck anticorps

Protein level used designations for HCK

hemopoietic cell kinase , non-receptor protein tyrosine kinase laloo , tyrosine-protein kinase HCK-like , hematopoietic cell kinase , p59-HCK/p60-HCK , tyrosine-protein kinase HCK , B cell/myeloid kinase , B-cell/myeloid kinase , p56-HCK/p59-HCK , hemopoietic cell tyrosine kinase , p56-HCK

GENE ID SPECIES
373700 Xenopus laevis
458163 Pan troglodytes
485828 Canis lupus familiaris
548439 Xenopus (Silurana) tropicalis
100455620 Pongo abelii
100587780 Nomascus leucogenys
3055 Homo sapiens
15162 Mus musculus
25734 Rattus norvegicus
419280 Gallus gallus
280814 Bos taurus
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