Aperçu des produits pour anti-TMEM173 (TMEM173) Anticorps

Full name:
anti-Transmembrane Protein 173 Anticorps (TMEM173)
Chez www.anticorps-enligne.fr sont 143 Transmembrane Protein 173 (TMEM173) Anticorps de 23 de différents fournisseurs disponibles. De plus, nous expédions TMEM173 Protéines (11) et TMEM173 Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 164 TMEM173 produits sont actuellement listés.
Synonymes:
2610307O08Rik, ERIS, Mita, MPYS, NET23, RGD1562552, STING
afficher tous les anticorps Gène GeneID UniProt
TMEM173 340061 Q86WV6
TMEM173 72512 Q3TBT3
TMEM173 498840  

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anti-Human TMEM173 Anticorps:

anti-Mouse (Murine) TMEM173 Anticorps:

anti-Rat (Rattus) TMEM173 Anticorps:

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anti-TMEM173 Anticorps mieux référencés

  1. Human Polyclonal TMEM173 Primary Antibody pour ICC, IF - ABIN4356573 : Furr, Chauhan, Moerdyk-Schauwecker, Marriott: A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells. dans Journal of neuroinflammation 2011 (PubMed)
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  2. Human Polyclonal TMEM173 Primary Antibody pour EIA, FACS - ABIN955253 : Sun, Li, Chen, Chen, You, Zhou, Zhou, Zhai, Chen, Jiang: ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. dans Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 4 references for 955253

  3. Human Polyclonal TMEM173 Primary Antibody pour WB - ABIN2783202 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... dans Genome research 2004 (PubMed)
    Show all 4 references for 2783202

  4. Human Monoclonal TMEM173 Primary Antibody pour FACS, ICC - ABIN4899624 : Schoggins, MacDuff, Imanaka, Gainey, Shrestha, Eitson, Mar, Richardson, Ratushny, Litvak, Dabelic, Manicassamy, Aitchison, Aderem, Elliott, García-Sastre, Racaniello, Snijder, Yokoyama, Diamond et al.: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. ... dans Nature 2014 (PubMed)
    Show all 2 references for 4899624

  5. Human Polyclonal TMEM173 Primary Antibody pour EIA, FACS - ABIN955254 : Zhong, Zhang, Lei, Li, Mao, Yang, Wang, Zhang, Shu: The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. dans Immunity 2009 (PubMed)
    Show all 2 references for 955254

Plus d’anticorps contre TMEM173 partenaires d’interaction

Human Transmembrane Protein 173 (TMEM173) interaction partners

  1. both IL-6 (Montrer IL6 Anticorps) and RIG-I (Montrer DDX58 Anticorps) are downstream molecules of STING along the DNA sensor pathway.

  2. We discuss three newly described monogenic autoinflammatory diseases [deficiency of adenosine deaminase 2 (Montrer CECR1 Anticorps) (DADA2), a subtype of macrophage activation syndrome (MAS (Montrer MAS1 Anticorps)), and stimulator of interferon (Montrer IFNA Anticorps) genes (STING)-associated vasculopathy with onset in infancy (SAVI)], discuss the possibilities of somatic mosaicism and digenic inheritance, and give an update on new concepts in pathways involved in familial Mediterranean fever (Montrer MEFV Anticorps)

  3. Structural analysis indicates that the 3 disease-associated mutations at positions 206, 281, and 284 of the STING protein define a novel cluster of amino acids with functional importance in the regulation of type I interferon (Montrer IFNA Anticorps) signaling

  4. a critical role of p38 (Montrer CRK Anticorps)-mediated USP21 (Montrer USP21 Anticorps) phosphorylation in regulating STING-mediated antiviral functions and identifies p38 (Montrer CRK Anticorps)-USP21 (Montrer USP21 Anticorps) axis as an important pathway that DNA virus adopts to avoid innate immunity responses.

  5. We conclude that the R71H-G230A-R293Q (HAQ) of TMEM173 is a null TMEM173 allele.

  6. Human herpesvirus 1 ICP27 interacted with TBK1 (Montrer TBK1 Anticorps) and STING in a manner that was dependent on TBK1 (Montrer TBK1 Anticorps) activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 (Montrer TBK1 Anticorps) pathway in human macrophages.

  7. Multivariate analysis supported TMEM173 as an independent prognostic factor.

  8. The mitochondrial damage-cGAS-STING-IRF3 (Montrer IRF3 Anticorps) pathway is critically involved in metabolic stress-induced endothelial inflammation.

  9. These data uncover a promycobacterial role for STING-dependent OASL (Montrer OASL Anticorps) production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen.

  10. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 (Montrer IRF3 Anticorps) and subsequent type I interferon (Montrer IFNA Anticorps) production. (Review)

Mouse (Murine) Transmembrane Protein 173 (TMEM173) interaction partners

  1. Yersinia YopJ negatively regulates IRF3 (Montrer IRF3 Anticorps)-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling.

  2. demonstrate that in colon tumor model, therapeutic anti-CD47 (Montrer CD47 Anticorps) preferentially relies on STING-mediated DNA sensing in dendritic cells

  3. STING is a central mediator of interferon (Montrer IFNA Anticorps) regulated inflammasome activation in Chlamydia trachomatis infection.

  4. this study shows that immune rejection of prostate cancer cells relies on Mus81 (Montrer MUS81 Anticorps) and STING

  5. TRIF (Montrer RNF138 Anticorps) and STING interacted directly, through their carboxy-terminal domains, to promote STING dimerization, intermembrane translocation, and signaling.

  6. We conclude that the R71H-G230A-R293Q (HAQ) of TMEM173 is a null TMEM173 allele.

  7. results show that resistance to HSV-1 in the trigeminal ganglia during acute infection is conferred in part by STING and IFN-alpha (Montrer IFNA Anticorps)/beta signaling in both bone marrow-derived and -resident cells, which coalesce to support a robust HSV-1-specific CD8 (Montrer CD8A Anticorps)(+) T cell response

  8. results suggest that LSm14A (Montrer LSM14A Anticorps) plays an important role in antiviral innate and adaptive immune responses by modulating MITA level in a cell type-specific manner

  9. STING and TRIF (Montrer RNF138 Anticorps) Contribute to Mouse Sepsis, Depending on Severity of the Disease Model

  10. Data suggest that activation of either RIG-I (Montrer DDX58 Anticorps)/MAVS (Montrer MAVS Anticorps) or STING pathways during acute intestinal tissue injury in mice resulted in IFN-I signaling that maintained gut (Montrer GUSB Anticorps) epithelial barrier integrity and reduced GVHD severity.

Pig (Porcine) Transmembrane Protein 173 (TMEM173) interaction partners

TMEM173 profil antigène

Antigen Summary

Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double- stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti- viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Alternative names and synonyms associated with TMEM173

  • transmembrane protein 173 (TMEM173) anticorps
  • transmembrane protein 173 (Tmem173) anticorps
  • 2610307O08Rik anticorps
  • ERIS anticorps
  • Mita anticorps
  • MPYS anticorps
  • NET23 anticorps
  • RGD1562552 anticorps
  • STING anticorps

Protein level used designations for TMEM173

transmembrane protein 173 , N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner , endoplasmic reticulum IFN stimulator , endoplasmic reticulum interferon stimulator , hMITA , hSTING , mediator of IRF3 activation , mitochondrial mediator of IRF3 activation , stimulator of interferon genes protein , MMITA , mSTING , Stimulator of interferon genes protein , mitochondrial transmembrane protein 173

GENE ID SPECIES
606815 Canis lupus familiaris
462107 Pan troglodytes
694353 Macaca mulatta
100459760 Pongo abelii
340061 Homo sapiens
72512 Mus musculus
533661 Bos taurus
768990 Gallus gallus
100217389 Sus scrofa
498840 Rattus norvegicus
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