MMP 9 anticorps (AA 1-708)

N° du produit ABIN1027712

Détail du produit anti-MMP 9 anticorps

Antigène: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Épitope: AA 1-708

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP 9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: Detecs ~92 kDa and ~82 kDa (pro and active forms).

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 1-708 (full length) of rat MMP9

Clone: S51-82

Isotype: IgG2a

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN1027712 was sufficient for detection of MMP9 in 20 μg of COS-1 cells (lysate) transfected with human MMP9 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Références pour anticorps anti-MMP 9 (ABIN1027712)

Ritzel, Doran, Glaser, Meadows, Faden, Stoica, Loane: "Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice." dans: Neurobiology of aging, Vol. 77, pp. 194-206, (2019) (PubMed).

Détails sur MMP 9

Antigène: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Autre désignation: MMP9 (MMP9 Produits)

Synonymes: anticorps CLG4B, anticorps GELB, anticorps MANDP2, anticorps MMP-9, anticorps AW743869, anticorps B/MMP9, anticorps Clg4b, anticorps pro-MMP-9, anticorps mmp-9, anticorps fgMMP-9, anticorps mmp9, anticorps ZFMMP-9, anticorps wu:fb02g06, anticorps wu:fb07b05, anticorps wu:fi98c09, anticorps wu:fj05a08, anticorps zgc:64165, anticorps clg4b, anticorps gelb, anticorps mandp2, anticorps matrix metallopeptidase 9, anticorps collagenase, anticorps matrix metalloproteinase 9, anticorps matrix metallopeptidase 9 S homeolog, anticorps MMP9, anticorps RB3913, anticorps BPSS0666, anticorps Sbal_3732, anticorps Bcer98_0486, anticorps Shew185_0630, anticorps Shal_3056, anticorps Sbal195_0657, anticorps Lbys_3550, anticorps Palpr_2084, anticorps Mmp9, anticorps mmp9, anticorps mmp9.S

Sujet: MMP9, otherwise known as matrix metalloproteinase 9, is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease processes like arthritis and metastasis (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).

ID gène: 81687

NCBI Accession: NP_112317

UniProt: P50282

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events