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CD82 anticorps

CD82 Reactivité: Humain WB, FACS, IHC (p), IP, ICC Hôte: Souris Monoclonal C33 unconjugated
N° du produit ABIN1043024
  • Antigène Voir toutes CD82 Anticorps
    CD82
    Reactivité
    • 65
    • 37
    • 6
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 28
    Souris
    Clonalité
    • 58
    • 29
    Monoclonal
    Conjugué
    • 30
    • 10
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD82 est non-conjugé
    Application
    • 56
    • 38
    • 28
    • 23
    • 19
    • 18
    • 13
    • 13
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificité
    The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
    Réactivité croisée (Details)
    Human, Other not tested
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    C91/PL (human HTLV-1+ T cell line)
    Clone
    C33
    Isotype
    IgG2a
    Top Product
    Discover our top product CD82 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." dans: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

    Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." dans: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

    Ueda, Ichikawa, Tamaru, Mikata, Akakura, Akimoto, Imai, Yoshie, Shiraishi, Yatani, Ito, Shimazaki: "Expression of the KAI1 protein in benign prostatic hyperplasia and prostate cancer." dans: The American journal of pathology, Vol. 149, Issue 5, pp. 1435-40, (1996) (PubMed).

    Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

    Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

    Fukudome, Furuse, Imai, Nishimura, Takagi, Hinuma, Yoshie et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." dans: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).

  • Antigène
    CD82
    Autre désignation
    CD82 (CD82 Produits)
    Synonymes
    anticorps AA682076, anticorps AL023070, anticorps C33, anticorps IA4, anticorps Kai1, anticorps Tspan27, anticorps 4F9, anticorps GR15, anticorps KAI1, anticorps R2, anticorps SAR2, anticorps ST6, anticorps TSPAN27, anticorps CD82 antigen, anticorps CD82 molecule, anticorps Cd82 molecule, anticorps Cd82, anticorps CD82
    Sujet
    CD82 Molecule,CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.,R2, 4F9, C33, IA4, ST6, GR15, KAI1, SAR2, TSPAN27
    ID gène
    3732
    UniProt
    P27701
    Pathways
    Signalisation p53
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