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IL-32 alpha anticorps (Biotin)

IL32A Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1043804
  • Antigène Voir toutes IL-32 alpha (IL32A) Anticorps
    IL-32 alpha (IL32A) (Interleukin 32 alpha (IL32A))
    Reactivité
    Humain
    Hôte
    • 4
    • 1
    Lapin
    Clonalité
    • 4
    • 1
    Polyclonal
    Conjugué
    • 2
    • 2
    • 1
    Cet anticorp IL-32 alpha est conjugé à/à la Biotin
    Application
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-32A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
    Attributs du produit
    IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32alpha, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Purification
    purified
    Immunogène
    This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-32A protein.
    Immunogen Type: RecombinantProtein
    Isotype
    IgG
  • Indications d'application
    This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to native human IL-32α protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Commentaires

    Gene Name: IL32

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Concentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Date de péremption
    12 months
  • Nishida, Andoh, Inatomi, Fujiyama: "Interleukin-32 expression in the pancreas." dans: The Journal of biological chemistry, Vol. 284, Issue 26, pp. 17868-76, (2009) (PubMed).

  • Antigène
    IL-32 alpha (IL32A) (Interleukin 32 alpha (IL32A))
    Autre désignation
    IL-32A (IL32A Produits)
    Synonymes
    anticorps IL-32alpha, anticorps IL-32beta, anticorps IL-32delta, anticorps IL-32gamma, anticorps NK4, anticorps TAIF, anticorps TAIFa, anticorps TAIFb, anticorps TAIFc, anticorps TAIFd, anticorps interleukin 32, anticorps IL32
    Sujet
    IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32α, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFα and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Synonyms: IL-32A, Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32α, Interleukin-32 and IL-32 isoform 4.
    ID gène
    9235, 61658634
    UniProt
    P24001
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