CCL20 anticorps (HRP)

N° du produit ABIN1043828

Détail du produit anti-CCL20 anticorps (HRP)

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL20 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Specificité: Mouse MIP-3 alpha Antibody Peroxidase Conjugated was heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant mouse MIP-3alpha in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.

Attributs du produit: MIP-3alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Purification: purified

Immunogène: MIP-3 alpha Antibody Peroxidase Conjugated was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant mouse MIP-3alpha protein.
Immunogen Type: Recombinant Protein

Isotype: IgG

Information d'application

Indications d'application: This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 10.7 kDa in size corresponding to mouse MIP-3α protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

Commentaires:

Gene Name: Ccl20

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Agent conservateur: Gentamicin sulfate

Conseil sur la manipulation: Do NOT add Sodium Azide!

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Date de péremption: 12 months

Références pour anticorps anti-CCL20 (HRP) (ABIN1043828)

Harper, Guo, Rizzo, Lillis, Kurtz, Skorcheva, Purdy, Fitch, Iordanov, Blauvelt: "Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis." dans: The Journal of investigative dermatology, Vol. 129, Issue 9, pp. 2175-83, (2009) (PubMed).

Détails sur CCL20

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Autre désignation: MIP-3 alpha (CCL20 Produits)

Synonymes: anticorps MIP-3ALPHA, anticorps CCL20, anticorps si:dkey-150o13.1, anticorps CKb4, anticorps LARC, anticorps MIP-3-alpha, anticorps MIP-3a, anticorps MIP3A, anticorps SCYA20, anticorps ST38, anticorps MIP-3A, anticorps MIP-3[a], anticorps Scya20, anticorps exodus-1, anticorps C-C motif chemokine ligand 20, anticorps chemokine (C-C motif) ligand 20b, anticorps chemokine (C-C motif) ligand 20, anticorps CCL20, anticorps ccl20b, anticorps Ccl20

Sujet: MIP-3α (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3α inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3α also possesses antibacterial activity against E.coli and S.aureus. MIP-3α is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Synonyms: MIP-3α , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1

ID gène: 20297

NCBI Accession: NP_058656

UniProt: Q642U4

Pathways: Phosphorylation & l'infection par le SRAS-CoV-2