SLPI anticorps
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- Antigène Voir toutes SLPI Anticorps
- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLPI est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- Specificité
- The antibody reacts with secretory leukocyte proteinase inhibitor (SLPI, also known as antileukoprotease (ALP)).
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Protein A
- Isotype
- IgG
- Top Product
- Discover our top product SLPI Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2 - 8 °C.
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- Antigène
- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
- Autre désignation
- Antileukoproteinase (ALP) (SLPI Produits)
- Synonymes
- anticorps ALK1, anticorps ALP, anticorps BLPI, anticorps HUSI, anticorps HUSI-I, anticorps MPI, anticorps WAP4, anticorps WFDC4, anticorps MATN4, anticorps SLPI, anticorps ckpi, anticorps secretory leukocyte peptidase inhibitor, anticorps antileukoproteinase, anticorps SLPI, anticorps Slpi, anticorps LOC102174044
- Sujet
- SLPI is a 11.7 kDa cationic inhibitor of neutrophil elastase and to a lesser extent of cathepsin G. It is locally produced by epithelial cells in the lung, skin and other organs, by Polymorphonuclear leukocytes (PMN) and (in mice) by macrophages. In addition to its proteinase inhibitory properties that may serve to protect against proteolytic injury, it was recently shown that SLPI also displays several other functions such as antimicrobial and anti-inflammatory activities. These appear to be independent of its ability to inhibit PMN serine proteinases. SLPI has also been demonstrated to display antibacterial and antifungal activity at concentrations in which SLPI is present in mucosal secretions including those of the lung. Another possible role for SLPI is inhibition of protein-disulphide isomerase that is considered essential for invasion of a cell by the Human Immunodeficiency Virus (HIV).Synonyms: BLPI, HUSI-1, Mucus proteinase inhibitor, Protease inhibitor WAP4, SLPI, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, WAP4, WFDC4
- ID gène
- 6590
- NCBI Accession
- NP_003055
- UniProt
- P03973
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