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SLPI anticorps

SLPI Reactivité: Humain WB, IP, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1105384
  • Antigène Voir toutes SLPI Anticorps
    SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
    Reactivité
    • 48
    • 10
    Humain
    Hôte
    • 39
    • 12
    • 3
    Lapin
    Clonalité
    • 43
    • 11
    Polyclonal
    Conjugué
    • 24
    • 11
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLPI est non-conjugé
    Application
    • 43
    • 24
    • 16
    • 12
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Specificité
    The antibody reacts with secretory leukocyte proteinase inhibitor (SLPI, also known as antileukoprotease (ALP)).
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Protein A
    Isotype
    IgG
    Top Product
    Discover our top product SLPI Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2 - 8 °C.
  • Antigène
    SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
    Autre désignation
    Antileukoproteinase (ALP) (SLPI Produits)
    Synonymes
    anticorps ALK1, anticorps ALP, anticorps BLPI, anticorps HUSI, anticorps HUSI-I, anticorps MPI, anticorps WAP4, anticorps WFDC4, anticorps MATN4, anticorps SLPI, anticorps ckpi, anticorps secretory leukocyte peptidase inhibitor, anticorps antileukoproteinase, anticorps SLPI, anticorps Slpi, anticorps LOC102174044
    Sujet
    SLPI is a 11.7 kDa cationic inhibitor of neutrophil elastase and to a lesser extent of cathepsin G. It is locally produced by epithelial cells in the lung, skin and other organs, by Polymorphonuclear leukocytes (PMN) and (in mice) by macrophages. In addition to its proteinase inhibitory properties that may serve to protect against proteolytic injury, it was recently shown that SLPI also displays several other functions such as antimicrobial and anti-inflammatory activities. These appear to be independent of its ability to inhibit PMN serine proteinases. SLPI has also been demonstrated to display antibacterial and antifungal activity at concentrations in which SLPI is present in mucosal secretions including those of the lung. Another possible role for SLPI is inhibition of protein-disulphide isomerase that is considered essential for invasion of a cell by the Human Immunodeficiency Virus (HIV).Synonyms: BLPI, HUSI-1, Mucus proteinase inhibitor, Protease inhibitor WAP4, SLPI, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, WAP4, WFDC4
    ID gène
    6590
    NCBI Accession
    NP_003055
    UniProt
    P03973
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