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PD-L1 anticorps (Biotin)

PD-L1 Reactivité: Humain FACS Hôte: Souris Monoclonal MIH3 Biotin
N° du produit ABIN2853592
  • Antigène Voir toutes PD-L1 Anticorps
    PD-L1 (CD274 (PD-L1))
    Reactivité
    • 170
    • 108
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 126
    • 62
    • 17
    • 4
    • 4
    • 1
    Souris
    Clonalité
    • 108
    • 104
    • 2
    Monoclonal
    Conjugué
    • 98
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cet anticorp PD-L1 est conjugé à/à la Biotin
    Application
    • 138
    • 104
    • 60
    • 40
    • 37
    • 28
    • 17
    • 17
    • 16
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody reacts with human CD274.
    Purification
    Protein A agarose
    Immunogène
    Full-length human PD-L1 transfected L cells
    Clone
    MIH3
    Isotype
    IgG1
    Top Product
    Discover our top product PD-L1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.02 mg/mL
    Buffer
    PBS, 0.09 % NaN3, 1 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 2 - 8 °C.
  • Antigène
    PD-L1 (CD274 (PD-L1))
    Autre désignation
    CD274 / PDL1 (PD-L1 Produits)
    Synonymes
    anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2
    Sujet
    Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
    ID gène
    29126
    NCBI Accession
    NP_054862
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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