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TLR1 anticorps (Biotin)

TLR1 Reactivité: Humain FACS, IF, IHC (p), IHC (fro), EIA Hôte: Souris Monoclonal GD2-F4 Biotin
N° du produit ABIN1106187
  • Antigène Voir toutes TLR1 Anticorps
    TLR1 (Toll-Like Receptor 1 (TLR1))
    Reactivité
    • 73
    • 49
    • 29
    • 4
    • 4
    • 1
    Humain
    Hôte
    • 73
    • 14
    • 2
    Souris
    Clonalité
    • 76
    • 13
    Monoclonal
    Conjugué
    • 37
    • 14
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLR1 est conjugé à/à la Biotin
    Application
    • 69
    • 36
    • 32
    • 29
    • 14
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Protein G
    Immunogène
    TLR1Fc
    Clone
    GD2-F4
    Isotype
    IgG1
    Top Product
    Discover our top product TLR1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.1 % bovine serum albumin
    Stock
    4 °C
    Stockage commentaire
    Store at 2 - 8 °C.
  • Antigène
    TLR1 (Toll-Like Receptor 1 (TLR1))
    Autre désignation
    CD281 / TLR1 (TLR1 Produits)
    Synonymes
    anticorps CD281, anticorps TIL, anticorps TIL. LPRS5, anticorps rsc786, anticorps toll like receptor 1, anticorps toll-like receptor 1, anticorps TLR1, anticorps Tlr1
    Sujet
    Toll-like receptors (TLR) are highly conserved throughout evolution and play an essential role in recognizing conserved motifs found in various pathogens and initiating an appropriate innate immune response. In human, ten members of the TLR family have been identified as type I transmembrane signaling receptors containing multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Mammalian responsiveness to microbial products may be mediated by combinations of TLRs, for example a co-operative effect is observed between TLR1 and TLR2 in response to bacterial lipoproteins. On the other hand, TLR 1 was shown to have the capacity to abrogate TLR4 signaling. In general, TLR1 is expressed at higher levels as compared to other TLRs. The highest expression of TLR1 is found in monocytes but it can also be expressed by macrophages, dendritic cells, B, T, and NK cells. In recent studies, several human TLR1 polymorphisms have been associated with impaired mycobacterial signaling and susceptibility to tuberculosis.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
    ID gène
    9606
    UniProt
    Q15399
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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