Desmoglein 2 anticorps (Extracellular Domain)
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- Antigène Voir toutes Desmoglein 2 (DSG2) Anticorps
- Desmoglein 2 (DSG2)
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Épitope
- Extracellular Domain
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Desmoglein 2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificité
- The monoclonal antibody 6D8 recognizes the extracellular domain of human desmoglein-2. Does not cross react with desmoglein-1 and desmoglein-3.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Protein G
- Immunogène
- Extracellular EC4 domain
- Clone
- 6D8
- Isotype
- IgG1
- Top Product
- Discover our top product DSG2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Desmoglein 2 (DSG2)
- Autre désignation
- Desmoglein-2 (DSG2 Produits)
- Synonymes
- anticorps DSG2, anticorps dsc, anticorps dsga, anticorps si:dkeyp-51f12.6, anticorps wu:fj23f02, anticorps ARVC10, anticorps ARVD10, anticorps CDHF5, anticorps CMD1BB, anticorps HDGC, anticorps AA408168, anticorps D18Ertd293e, anticorps desmoglein 2, anticorps desmoglein 2, tandem duplicate 1, anticorps DSG2, anticorps dsg2.1, anticorps dsg2, anticorps Dsg2
- Sujet
- Desmogleins and desmocollins are members of the cadherin family of transmembrane proteins that together make up the core of the desmosome, a structure that provides transmembrane strength to tissues undergoing mechanical stress. The desmosomal cadherins, desmogleins and desmocollins, mediate calcium-dependent cell-cell adhesion by forming homotypic and heterotypic interactions with one another. The multiprotein desmosomal complex also includes the cytoplasmic desmosomal plaque proteins plakoglobin, phakophilins, and desmoplakin, which bind to the intracellular domain of the desmogleins and function to anchor the keratin intermediate filament network to site of cell-cell contacts.Synonyms: CDHF5, Cadherin family member 5, DSG2, HDGC
- ID gène
- 1829
- NCBI Accession
- NP_001934
- UniProt
- Q14126
- Pathways
- Cell-Cell Junction Organization
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